Clinical trials: Neurogenic Bowel Dysfunction, open to volunteers
Spinal Cord Injury, Neurogenic Bowel
Time Comparison of Interventions on Bowel Programs in Spinal Cord Injury
The goal of the study is to find out which of three different options (a suppository, a mini enema, or a transanal irrigation device) takes the least amount of time for completing bowel program amongst those who have spinal cord…
- Trial name
- NCT07817199
- Testing
- Suppository, Enemeez, Peristeen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Spinal Cord Injuries, Neuromodulation
Improving Pelvic Rehabilitation Using Epidural Stimulation After Spinal Cord Injury
The investigators will recruit up to 20 volunteers with chronic, supra-sacral SCI. Following screening, eligible participants will enter 'Phase I', they will complete baseline outcome measures and then have the epidural spinal…
- Conditions
- Spinal Cord Injuries, Neuromodulation, Neurogenic Bladder, Neurogenic Bowel
- Trial name
- ImPRESS (NCT06515223)
- Testing
- Epidural Spinal Cord Stimulation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Chronic Spinal Cord Injury
Abdominal Electrical Stimulation for Bowel Dysfunction in SCI
Many people with spinal cord injury (SCI) have bowel problems resulting in constipation and need a long time to empty the bowel. Some people spend an hour or more to empty their bowel.
- Trial name
- NCT06948175
- Testing
- Abdominal transcutaneous electrical stimulation (TES)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Neurogenic Bowel Dysfunction, Spinal Cord Injury
Kinesio Taping for Neurogenic Bowel Dysfunction in Spinal Cord Injury
Neurogenic bowel dysfunction is a common complication of spinal cord injury and may cause constipation, difficulty with defecation, prolonged bowel care, incomplete evacuation, fecal incontinence, and reduced quality of life.
- Trial name
- NCT07705984
- Testing
- Kinesio Taping, Routine Bowel Management Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Multiple Sclerosis, Pelvic Floor Disorder
RedCord in Neurogenic Bowel Dysfunction in Multiple Sclerosis
The study aims to evaluate the effectiveness of Redcord treatment for neurogenic bowel dysfunction in patients with multiple sclerosis.
- Trial name
- NCT06838624
- Testing
- Redcord, Control (Standard treatment)
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- University of Castilla-La Mancha
Spinal Cord Injury
At-Home Genital Nerve Stimulation for SCI Bowel
The purpose of this study is to test whether electrical stimulation of the skin in the pelvic area (near the genitals) can reduce the reflexes that cause bowel accidents in people with spinal cord injuries.
- Trial name
- NCT06836739
- Testing
- Genital nerve stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MetroHealth Medical Center
Spinal Cord Injury, Neurogenic Bowel Dysfunction
Artificial Int: Neurogenic Bowel Education in Spinal Cord Injury Patients
The aim of this study is to evaluate the effectiveness of patient education delivered through an artificial intelligence (AI)-based mobile application in the management of neurogenic bowel dysfunction in individuals with spinal…
- Trial name
- ArtInt (NCT07369349)
- Testing
- Mobil Application
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Senem Duman
Spinal Cord Injuries, Neurogenic Bowel
Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury
The primary objective of this study is to gather information about the effectiveness of abdominal FES to improve bowel management time (BMT) for people with chronic SCI.
- Trial name
- NCT06345781
- Testing
- Abdominal Functional Electrical Stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Craig Hospital
Spinal Cord Injury, Autonomic Dysfunction
Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury
This study is a pilot clinical trial to explore the efficacy of transcutaneous spinal cord stimulation (TCSCS) (proof-of-concept) in mitigating crucial autonomic dysfunctions that impact the health-related quality of life of…
- Conditions
- Spinal Cord Injury, Autonomic Dysfunction, Sexual Dysfunction, Neurogenic Bladder Dysfunction
- Trial name
- NCT05369520
- Testing
- TESCoN or SCONE device - Thoracic stimulation, TESCoN or SCONE device - Lumbosacral stimulation
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis
Sacral Neuromodulation for Neurogenic Lower Urinary Tract, Bowel and Sexual Dysfunction
A multi-center double-blinded placebo-controlled randomized clinical trial. The patients will be randomized into two groups. To investigate the efficacy of SNM to improve the key bladder diary variables compared to placebo (i.e.
- Conditions
- Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis, Sacral Neuromodulation, Bowel Dysfunction
- Trial name
- NCT05380856
- Testing
- Turning ON the neuromodulator, Turning OFF the neuromodulator
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Inflammatory Bowel Disease (IBD)
Biophysical Assessments of Acupuncture Points in Inflammatory Bowel Disease
Acupuncture points or acupoints are fundamental to the practice of acupuncture, yet their scientific basis remains unclear. According to traditional explanations of acupuncture, acupoints can become tender or more sensitive to…
- Trial name
- NCT07681895
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Spinal Cord Injuries
Efficacy of a Wearable Noninvasive Neuromodulation Device
The aim of this study is to investigate the potential of transcutaneous neuromodulation (TNM) to treat slow colonic transit and constipation, termed the Neurogenic bowel dysfunction (NBD), in people with SCI.
- Trial name
- NCT07171489
- Testing
- TNM at a leg point (AccelBand)- randomized arm, TNM at a leg point (AccelBand)- open-label
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Neurogenic Bowel Dysfunction, Spinal Cord Injury
Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction
The goal of this study is to test the safety and effectiveness of Vibrant capsules in spinal cord injury patients with neurogenic bowel.
- Trial name
- NCT07213986
- Testing
- Vibrant Capsule
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fecal Incontinence
Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury
Bowel issues occur in nearly all people after spinal cord injury (SCI) and one major complication is fecal incontinence (accidents).
- Trial name
- NCT05626816
- Testing
- Genital Nerve Stimulation, Clinical exam, Collection of SCI common data elements
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- MetroHealth Medical Center
Neurogenic Bowel, Spinal Cord Injuries (SCI)
Transcutaneous Spinal Cord Stimulation for Bowel Management in Individuals with Motor Complete Spinal Cord Injury
The primary goals of this pilot trial are to understand the feasibility and safety of thoracolumbar transcutaneous spinal cord stimulation for neurogenic bowel management in individuals with new onset, traumatic, cervicothoracic…
- Trial name
- NCT06801431
- Testing
- Transcutaneous spinal cord stimulation
- Volunteers
- 5 people
- Sponsor
- Nova Scotia Health Authority
Spinal Cord Injury, Detrusor Overacitivity
Effects of Sacral and Tibial Stimulation on Bladder Function in Subacute Suprasacral Spinal Cord Injury
Suprasacral spinal cord injury (SCI) frequently leads to neurogenic detrusor overactivity (NDO), resulting in elevated bladder storage pressures, urinary incontinence, and an increased risk of upper urinary tract damage.
- Trial name
- NCT07343583
- Testing
- Transcutaneous Tibial Nerve Stimulation, Transcutaneous Sacral Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Spina Bifida, Neurogenic Bowel
Bowel Continence Across the Lifespan in People With Spina Bifida
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida.
- Conditions
- Spina Bifida, Neurogenic Bowel, Bowel Incontinence
- Trial name
- BCALS (NCT07390318)
- Testing
- Retrograde Enema, Antegrade Enema
- Where
- 24 sites in United States
- Volunteers
- 943 people
- Sponsor
- David Chu
Neurogenic Bowel Dysfunction
Stimulation for Bowel Emptying
The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which…
- Trial name
- NCT06078176
- Testing
- Electrical Rectal Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- VA Office of Research and Development