Clinical trials: Neurologic Ambulation Disorder
Stroke
Powered Orthotic Exoskeleton Training in Stroke
Veterans who suffer strokes often have disturbances in the ability to walk that reduces independence and quality of life. Alterations in gait combined with general decreased activity are associated with reduced muscle strength of…
- Trial name
- POETS (NCT04241848)
- Testing
- Keeogo, Ambulation training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- VA Office of Research and Development
Stroke
Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke
Of the ~700,000 persons who suffer a stroke each year, only 50% recover the ability to perform unlimited community walking. One mechanism contributing to locomotor dysfunction post-stroke is an increased metabolic cost of walking…
- Trial name
- NCT00721357
- Testing
- Treadmill walking, Magnetic resonance spectroscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Study of Fampridine-SR Tablets in Multiple Sclerosis Patients
The purpose of the study is to show that individuals treated with Fampridine-SR tablets are significantly more likely to have consistent improvements in their walking than those treated with placebo tablets.
- Trial name
- NCT00483652
- Testing
- Fampridine-SR
- Where
- 40 sites in United States, Canada
- Volunteers
- 240 people
- Sponsor
- Acorda Therapeutics
Incomplete Spinal Cord Injury
Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury
Spinal cord injury (SCI) affects ~42,000 Veterans. The VA provides the single largest network of SCI care in the nation. The lifetime financial burden of SCI can exceed $3 million. A major cost of SCI is impaired mobility.
- Trial name
- AGILE SCI (NCT04340063)
- Testing
- Gait training performed on a treadmill, Gait training performed in a Movement Amplification Environment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Cerebral Palsy
Effect of Dysport Injections on Energy Expenditure and Walking Efficiency in Children With Cerebral Palsy
This study aims to evaluate the efficacy of single event multi level chemoneurolysis with the abobotulinumtoxin A drug, Dysport®, on walking energy expenditure and gait in children with spastic diplegia cerebral palsy.
- Trial name
- NCT03469999
- Testing
- Dysport Injectable Product
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Cerebral Palsy
Intensive Home-based Treadmill Training and Walking Attainment in Young Children With Cerebral Palsy
This study is designed to find the optimal dosage of home-based treadmill training needed to accelerate walking onset and to examine the long-term effects on the child's walking activity.
- Trial name
- NCT02424526
- Testing
- home-based treadmill training, Treadmill
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- California State University, Sacramento