Clinical trials: Neurologic Complication
Bariatric Surgery Candidate, Postoperative Pain
Postoperative VR for Recovery After Bariatric Surgery
The objective of this study is to investigate whether the addition of immersive virtual reality (VR) in the immediate postoperative period to an enhanced recovery after surgery (ERAS) protocol could improve postoperative recovery…
- Conditions
- Bariatric Surgery Candidate, Postoperative Pain, Postoperative Complications
- Trial name
- NCT04754165
- Testing
- Virtual Reality Immersive Relaxation
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hypertension
A Trial of Telmisartan Prevention of Cardiovascular Disease
The present research is conducted as a randomized, parallel-group, controlled, open study (using the PROBE method) to primarily verify the effects on various biomarkers in high-risk hypertensive patients treated with ARB…
- Trial name
- ATTEMPT-CVD (NCT01075698)
- Testing
- Non-ARB (standard therapy), ARB (Telmisartan)
- Where
- Japan
- Volunteers
- 1,228 people
- Sponsor
- Kumamoto University
Diabetic Neuropathies, Neuropathic Pain
Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo.
- Conditions
- Diabetic Neuropathies, Neuropathic Pain, Pain, Chronic
- Trial name
- NCT03664921
- Testing
- Omnitram Oral Tablet
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Syntrix Biosystems, Inc.
Analgesia, Pain, Post Operative
Comparison of OSTAP and EOIP Blocks in Laparoscopic Cholecystectomies
Laparoscopic cholecystectomy (LC) surgery causes postoperative severe pain. As part of multimodal analgesia aimed at reducing postoperative opioid consumption and providing effective analgesia, ultrasound (US)-guided transversus…
- Trial name
- NCT06172465
- Testing
- EOIP, OSTAP
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samsun University
Intracranial Pressure Increase, Mechanical Ventilation Complication
Lung Recruitment and PEEP Effects on Intracranial Pressure in Cranial Surgery
High positive end-expiratory pressure (PEEP) levels required to achieve clinical benefits may increase ICP and reduce cerebral perfusion pressure (CPP) in patients at risk of intracranial hypertension.
- Trial name
- NCT06771232
- Testing
- Subdural pressure measurement
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Postoperative Nausea, Adverse Effects
Safety and Tolerability of Controlled-release Oxycodone on Postoperative Pain in Oncologic Head and Neck Surgery
The hypothesis of this study is that controlled release oxycodone can be safe and well tolerated for the control of postoperative pain in surgery for head and neck cancer.
- Conditions
- Postoperative Nausea, Adverse Effects, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT01834898
- Testing
- Controlled-release oxycodone
- Where
- Brazil
- Volunteers
- 83 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Pain, Post Operative Pain
Erector Spina Plane Block for Multilevel Major Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.
- Trial name
- NCT05983393
- Testing
- Erector spinae plane block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Spinal Deformity, Trauma
Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients
Surgical site infections (SSI) are not uncommon, especially in specific high-risk groups including spinal deformity and tumor (i.e. metastatic spine surgery) surgery.
- Conditions
- Spinal Deformity, Trauma, Spinal Tumor, Surgical Site Infection
- Trial name
- NCT03839914
- Testing
- Vancomycin powder
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Lumbago, Anxiety
Assessment of the Effectiveness of a Program of Preparation to Pregnancy and Delivery
Introduction: randomized studies on programs implemented during pre-natal care that offer information and physical activities preparing pregnant women for delivery are scarce in the scientific literature.
- Trial name
- NCT01155804
- Testing
- preparation of the delivery
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Center for Research on Reproductive Health of Campinas
Brain Injuries, Infant, Premature
SafeBoosC - a Phase II Trial
Background 25,000 infants are born extremely preterm every year in Europe. This group of infants carries a high risk of death and subsequent cerebral impairment for the infant, especially in the first 72 hours of life.
- Trial name
- SafeBoosC (NCT01590316)
- Testing
- Cerebral NIRS oximetry
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Gorm Greisen
Multiple Sclerosis
Identification of Factors Related to UI in Patients With MS and EMG Assessment of PFM Activity
The study aimed to explore the link between urinary incontinence (UI) severity in patients with multiple sclerosis (PwMS), electromyography (EMG) findings, and other relevant factors.
- Trial name
- NCT07236684
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Artvin Coruh University
Pain Vulva
Application of Cheek Acupuncture in Vaginal Tightening Surgery
A large number of studies have shown that acupuncture can reduce perioperative pain in patients. Cheek acupuncture therapy is a new acupuncture treatment, which belongs to the microneedle system, that is, acupuncture at specific…
- Trial name
- NCT06587711
- Testing
- acupuncture treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Postoperative Pain, Inflammation
Assessment of the Operative Course in Connection With Removal of Lower Third Molars
The aim of this study is to compare postoperative complications after removal of lower third molars using two different types of anaesthetics and two different treatments against swelling and inflammation (methylprednisolone and…
- Trial name
- NCT00805298
- Testing
- methylprednisolone, xyloplyin adrenalin, marcain adrenalin
- Where
- Denmark
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pain Management After Surgery
Evaluation of the Effect of Virtual Reality Application on Postoperative Pain and Anxiety in Women Aged 50-70
Surgical interventions, while significant milestones in patients\' physical recovery processes, can be a major source of concern for patients due to postoperative pain, which is also an important component of postoperative…
- Trial name
- Pain (NCT06436014)
- Testing
- Providing VR experience
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Osmaniye Korkut Ata University
Asymptomatic Apical Periodontitis
Sonic Irrigation Activation for Postoperative Pain After Root Canal Treatment
This randomized controlled clinical trial will evaluate whether sonic activation of the root canal irrigant using the EndoActivator system reduces postoperative pain after root canal treatment compared with conventional syringe…
- Trial name
- VAS (NCT07847333)
- Testing
- Sonic Irrigation Activation Using EndoActivator, Conventional Syringe Irrigation
- Volunteers
- 176 people
- Sponsor
- Saidu College of Dentistry
Urinary Incontinence, Urinary Incontinence, Urge
Prophylactic Analgesia for Bladder Botox Injections
The goal of this clinical trial is to learn more about using phenazopyridine (Pyridium) for pain control during bladder onabotulinumtoxinA ("botox") injections for surgical management of overactive bladder (OAB) for patients at…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Overactive Bladder
- Trial name
- NCT06514430
- Testing
- Phenazopyridine, 1% lidocaine with sodium bicarbonate
- Where
- United States
- Sponsor
- Montefiore Medical Center
Ureter Stone
Effectiveness Basket Wires for the Maintenance of Stone and Pneumatic Probe in the Treatment of Ureteral Stones
Patients included in the study included the necessary tests U / A, K, Na, Cr, BUN, CBC, And U / C was checked and anesthesia counseling was done. Patients were prepared for action.
- Trial name
- NCT03980444
- Testing
- Basket of wire, control group, no basket
- Where
- 2 sites in Iran
- Volunteers
- 124 people
- Sponsor
- Mohammad Sadegh Bagheri Baghdasht
Post Operative Pain, Apical Periodontitis
Influence of Sonic Activation of Root Sealers on Post-Operative Pain
Aim: This clinical study aims to compare post-operative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin based AH Plus and calcium silicate based Endosequence BC…
- Trial name
- NCT06403293
- Testing
- Root canal treatment (AH Plus-NA), Root canal treatment (AH Plus-EA), Root canal treatment (BC-NA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Postoperative Pain
Factors Predicting Postoperative Cesarean Section Pain
In spite of identical analgesic protocols, parturients suffer different levels of pain postoperative lay. In this study we hope to identify factors which influence the perception of pain including preoperative anxiety, sleep…
- Trial name
- NCT02033304
- Where
- 2 sites in Israel
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Pain, Postoperative, Premature Infant
Postoperative Pain Control & Relief in Neonates
Pain control for newborns has made significant improvements over the last 30 years. The use of narcotics remains the standard of care for neonates undergoing minor and major surgeries.
- Conditions
- Pain, Postoperative, Premature Infant, Opioid Use
- Trial name
- POPCORN (NCT03677830)
- Testing
- Acetaminophen, Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Louis University
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