Clinical trials: Neurologic Complication
Endometriosis
Effects of Intravenous Lidocaine on Endometriosis Pain
We are doing this research study to find out if intravenous (in your vein, "IV") lidocaine can lessen pain from endometriosis. The U.S.
- Trial name
- NCT01968694
- Testing
- IV Lidocaine, IV diphenhydramine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Insomnia, Post Partum Depression
Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression
The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms.
- Trial name
- PPD (NCT03596879)
- Testing
- dCBTI, Sleep Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Henry Ford Health System
Cardiac Arrest
Vitamin C in Post-cardiac Arrest
Only half of the patients suffering from cardiac arrest arrive at the hospital alive. Of these survivors, more than 50% will still die or remain severely disabled.
- Trial name
- VITaCCA (NCT03509662)
- Testing
- Vitamin C, Thiamine
- Where
- Netherlands
- Volunteers
- 270 people
- Sponsor
- Amsterdam UMC, location VUmc
Kidney Stone
An Analgesia Protocol for Acute Renal Colic in the Emergency Department
An analgesia protocol for acute renal colic will lead to faster significant reductions in pain than prior practice.
- Trial name
- NCT00504283
- Testing
- Toradol, Morphine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Inguinal Hernia, Postoperative Pain
TENS for Pain and Sleep After Hernia Surgery
This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Sleep Disturbance
- Trial name
- TENS-HERNIA (NCT07319754)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
General Anesthesia
The Relationship Between the SPI and the Postop ED
Surgical plethysmography index (SPI) is a device that can noninvasively monitor the balance between the nociception and ant-nociception using pulse photoplethysmographic amplitude (PPGA) and heart rate obtained through an oxygen…
- Trial name
- SPI_ED (NCT03328910)
- Testing
- SPI monitor (GE Healthcare, Helsinki, Finland)
- Where
- South Korea
- Sponsor
- Daegu Catholic University Medical Center
Spinal Cord Injury, Neurogenic Bladder (NB)
Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD
The main objective of the proposed research study is to determine in men and women with spinal cord injury/disease and neurogenic bladder whether the dose of coupled gentamicin \& Lactobacillus rhamnosus GG affects the…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder (NB), Neurogenic Lower Urinary Tract Dysfunction, Multiple Sclerosis
- Trial name
- NCT07643974
- Testing
- Gentamicin, Lactobacillus Rhamnosus GG
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Medstar Health Research Institute
Postoperative; Dysfunction Following Cardiac Surgery
Cerebral Energy State in Cardiac Surgery
Impaired cerebral function remains an important complication of cardiopulmonary bypass (CPB) during cardiac surgery. The aim of the present study is to investigate whether the lactate to pyruvate (LP) ratio obtained by…
- Trial name
- NCT02846818
- Testing
- Microdialysis
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Postoperative Delirium
Risk Factors for Postoperative Delirium in Elderly Patients Undergoing Major Non-Cardiac Surgery in Singapore
The primary aim is to establish the risk factors, in particular the modifiable risk factors, for the development of POD in elderly patients undergoing major non-cardiac surgery in a tertiary hospital in Singapore.
- Trial name
- NCT04617210
- Testing
- Neurocognitive tests and blood taking
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University Hospital, Singapore
Cancer Breast, Hypovitaminosis D
Influence of Preoperative Vitamin D Level on Postoperative Pain in Breast Cancer Surgery Patients
Vitamin D deficiency is a general problem that vigorously affects human health . Breast cancer is the most frequently diagnosed life-threatening cancer in women and the leading cause of cancer death among women.Vitamin D…
- Trial name
- NCT06551688
- Testing
- Serum 25(OH)D level
- Where
- Egypt
- Volunteers
- 184 people
- Sponsor
- Fayoum University
Pain, Postoperative, Opioid Use
Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis
Pediatric spinal fusion (PSF) surgery is a painful procedure that can treat adolescent idiopathic scoliosis (AIS). One technique that can potentially reduce patients' pain levels and need for opioid medication is the…
- Conditions
- Pain, Postoperative, Opioid Use, Recruitment
- Trial name
- NCT04500613
- Testing
- Bilateral Erector Spinae Plane Block with bupivacaine and dexamethasone, No bilateral Erector Spinae Plane Block (no bupivacaine and no dexamethasone)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Pain
Efficacy of Preventive Ketamine on Postoperative Pain
Although bariatric surgery is mainly performed laparoscopically, analgesic optimization is still essential to reduce complications and to improve the patients' comfort.
- Trial name
- NCT04908579
- Testing
- bupivacaine(intraperitoneally) and ketamine (intraperitoneally), bupivacaine(intraperitoneally) and ketamine (intravenously), bupivacaine(intraperitoneally)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Post Operative Pain
Effect of NeoSEALER FLO and AH Plus Resin Sealer on Postoperative Pain and Healing of Periapical Lesions
Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing.The success…
- Trial name
- NCT07785973
- Testing
- AH plus sealer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Minia University
Anesthesia, Local, Pain, Postoperative
Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks
The purpose of this study is to determine if there is any significant difference between using a short-term ON-Q nerve block (which is applied prior to surgery and maintained in place until the medication in the initial balls…
- Trial name
- NCT03245359
- Testing
- Short-term ON-Q, Long-term ON-Q
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AdventHealth
Complications Due to Coronary Artery Bypass Graft, Coronary Artery Disease
Neurological Complications Comparing Endoscopically vs. Open Harvest of the Radial Artery
Coronary artery bypass grafting (CABG) using the radial artery (RA) has since the nineties gone through a revival. The initially reported worse outcome in RA graft patients compared to patients grafted with the saphenous vein…
- Conditions
- Complications Due to Coronary Artery Bypass Graft, Coronary Artery Disease, Myocardial Ischemia, Coronary Disease
- Trial name
- NEO (NCT01848886)
- Testing
- Endoscopic radial artery harvest, Open radial artery harvest, Mammarioradial graft (Y-graft)
- Where
- Denmark
- Volunteers
- 301 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Emergence Agitation
Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery
The study is conducted to evaluate the effects of dexmedetomedine in subtenon's block in conjunction to general anesthesia under sevoflurane anesthesia on emergence agitation, intraoperative hemodynamic stability, postoperative…
- Trial name
- NCT04485273
- Testing
- Laryngeal Mask Airway, Sevoflurane, Subtenon's Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Postoperative Pain
Effect of Infusion of Lidocaine, Magnesium and Remifentanil Perioperatively in Patients Undergoing Mastectomy
This study aims to compare the quality of perioperative analgesia of lidocaine, magnesium sulphate and remifentanil in patients undergoing mastectomy
- Trial name
- NCT02309879
- Testing
- Remifentanil infusion, Lidocaine infusion, Magnesium sulphate infusion
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Base
Endometriosis, Pain
Efficacy Study of Atorvastatin in Pelvic Pain Relief in Women With Endometriosis
The purpose of this study is to determine whether atorvastatin (alone or in combination with oral contraceptive) is effective in treatment of pelvic pain and inflammatory response in women with endometriosis.
- Trial name
- EndoStatin (NCT00675779)
- Testing
- oral contraceptive (Mercilon), atorvastatin + oral contraceptive
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Poznan University of Medical Sciences
Pain, Postoperative, Analgesia
Prediction of Postoperative Pain by Nociception Monitoring
General anesthesia is a combination of hypnotic drugs and opioid analgesics. Modern general anesthesia aims to treat nociception induced by surgical stimulation while avoiding an overdose of opioid analgesics and reducing…
- Conditions
- Pain, Postoperative, Analgesia, Anesthesia Recovery Period, Opioid Use
- Trial name
- PredictPain (NCT05063227)
- Testing
- Observational: analgesia monitoring indices and changes in heart rate
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
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