Clinical trials: Neurologic Complication
Pain, Postoperative, Arthroplasty, Replacement, Knee
Liposomal Bupivacaine in Total Knee Arthroplasty
Liposomal bupivacaine is a novel local anesthetic designed for prolonged pain relief. Despite its long-acting analgesic potential, liposomal bupivacaine is significantly more expensive than other local anesthetic alternatives.
- Conditions
- Pain, Postoperative, Arthroplasty, Replacement, Knee, Osteoarthritis
- Trial name
- NCT02426164
- Testing
- Liposomal bupivacaine, bupivacaine HCl, morphine, epinephrine, methylprednisolone
- Where
- United States
- Sponsor
- Miller Orthopedic Specialists
Chronic Postoperative Pain, Cesarean Section Complications
Monocentric Observational Study: Postoperative Pain After Cesarean Section: Incidence and Risk Factors.
The purpose of this prospective study was to assess chronic pain 3, and 12 months after cesarean delivery in a cohort of women in University hospital La Paz.
- Trial name
- NCT04280432
- Testing
- CESAREAN
- Where
- Spain
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pain, Postoperative, ACL
Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction
Liposomal bupivacaine injectable suspension (Exparel), manufactured by Pacira Pharmaceuticals, is an FDA-approved, long-lasting nonopioid analgesic that is indicated for single-dose infiltration in adults to produce postsurgical…
- Trial name
- NCT05161221
- Testing
- OxyCODONE 5 mg Oral Tablet, Naproxen 500 Mg, Tylenol Pill
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Phantom Limb Pain
Incidence and Factors Affecting the Development and Outcome of Phantom Limb Pain (PLP) - A Single-centre Prospective Cohort Study.
Phantom limb pain (PLP), defined as pain felt in the missing portion of the amputated limb following amputation, occurs in a significant percentage of patients who undergo limb amputation and it is among the most difficult…
- Trial name
- NCT05005481
- Testing
- NIL intervention
- Where
- Singapore
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Pain
Local Infiltration Analgesia After Abdominal Hysterectomy
The aim of the study is to evaluate traditional analgesic therapy after abdominal hysterectomy with single infiltration of local anesthetics in the surgical area at the end of surgery.
- Trial name
- LIA (NCT01782781)
- Testing
- ropivacaine, ketorelac and epinephrine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Postoperative Pain
Clonidine for Infra-orbital Nerve Block During Pediatric Cleft Lip Revision Surgeries
Pain in children is usually an undertreated entity. Undertreating perioperative pain could lead to various metabolic, physiologic, and neurophysiological responses.
- Trial name
- NCT05790044
- Testing
- Bupivacaine, Clonidine
- Volunteers
- 86 people
- Sponsor
- Assiut University
Abdomen, Acute, Surgery--Complications
Survival After Emergency Laparotomy in Octogenarians
In this single-center retrospective study we wanted to investigate mortality and postoperative complications after emergency laparotomy performed in patients aged 80 years or above.
- Conditions
- Abdomen, Acute, Surgery--Complications, Postoperative Complications, Frailty
- Trial name
- NCT04176432
- Testing
- No intervention
- Volunteers
- 106 people
- Sponsor
- Haukeland University Hospital
Menstrual Migraines, Menstrual Bleeding
Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives.
This study will examine the combined effects of a continuous oral contraceptive (OC) regimen with supplemental estradiol therapy on headache severity and occurrence in subjects with documented Menstrually Associated Migraines…
- Conditions
- Menstrual Migraines, Menstrual Bleeding, Menstrual Spotting
- Trial name
- Estradiol/MAM (NCT01251263)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Anterior Cruciate Ligament Reconstruction
A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery
The purpose of the study is to determine if there is difference in immediate postoperative pain levels (48 hours) between patients who wear a knee immobilizer splint compared to patients who do not wear a knee immobilizer splint…
- Trial name
- NCT00338663
- Testing
- knee immobilization splint
- Where
- 2 sites in Canada
- Volunteers
- 88 people
- Sponsor
- LifeMark Health Research Group
Postoperative Delirium
Methylene Blue and Postoperative Neurocognitive Disorders
Postoperative Neurocognitive Disorders are the most common neurological complications after major surgery, which are associated with higher increased mortality and morbidity in elderly patients undergoing major surgery.
- Trial name
- NCT04529265
- Testing
- Methylene Blue
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Fudan University
Symptomatic Apical Periodontitis
Postoperative Pain and Substance P Levels After Bioceramic vs Calcium Hydroxide Intracanal Medicaments in Symptomatic Apical Periodontitis
Clinical Evaluation of the Postoperative Pain and Substance P levels Following the use of Bioceramic verses Calcium Hydroxide Intracanal Medicaments in Permanent Mandibular molars with Symptomatic Apical Periodontitis
- Trial name
- (BCvsCaOH) (NCT07585721)
- Testing
- Calcium Hydroxide (Ca(OH)2), Bioceramic Intracanal Medicament
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Cardiac Pacing, Permanent Pacemaker Implantation
Ultrasound-Guided PECS II Block for Permanent Pacemaker Implantation
This single-center, prospective, randomized, controlled clinical trial aims to evaluate whether ultrasound-guided PECS II block, when added to standard local infiltration anesthesia, improves perioperative analgesia in patients…
- Conditions
- Cardiac Pacing, Permanent Pacemaker Implantation, Postoperative Pain
- Trial name
- PACE-PECS (NCT07739407)
- Testing
- Ultrasound-Guided PECS II Block, Standard Local Infiltration Anesthesia
- Volunteers
- 72 people
- Sponsor
- ferdi gülaştı
Total Knee Arthroplasty, Postoperative Pain
Rebound Pain After Peripheral Nerve Blocks in Total Knee Arthroplasty
This prospective observational study aims to determine the incidence and clinical impact of rebound pain after peripheral nerve blocks in patients undergoing total knee arthroplasty.
- Conditions
- Total Knee Arthroplasty, Postoperative Pain, Rebound Pain, Peripheral Nerve Block
- Trial name
- NCT06966011
- Where
- Turkey (Türkiye)
- Volunteers
- 294 people
- Sponsor
- Konya City Hospital
Sacroiliac Joint, Pain
Sacroiliac (SI) Screws: The Effect of SI Screw Removal on Patient-Reported Pain and Functional Outcomes
Chronic pain following surgical stabilization of a pelvic fracture is very prominent and can have a major affect on a patient's quality of life.
- Conditions
- Sacroiliac Joint, Pain, Pelvis
- Trial name
- SIS (NCT02652611)
- Testing
- SI Screw Removal Surgery, Non-screw removal treatment (non-operative management)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Maryland, Baltimore
Postoperative Pain, Intracranial Hypertension
The Effect of Caudal Block on Optic Nerve Sheath Diameter in Pediatric Patients
Caudal epidural block has been a widely used regional anesthesia method, especially in pediatric surgery, to provide intraoperative and postoperative analgesia.
- Trial name
- NCT05216211
- Testing
- Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Urinary Calculi, Emergency Service, Hospital
Analysis the Relationship Between the Abdomen CT and Outcomes in Acute Urinary Stone Patients
This is an observational study based on retrospectively collected data of ureter stone patients between 2011 and 2014. Aim of study is to determine radiologic findings of non-contrast abdominal computerized tomography as…
- Trial name
- NCT02983409
- Testing
- Pstone
- Volunteers
- 862 people
- Sponsor
- Konkuk University Medical Center
Diabetes Mellitus, Type 1, Diabetic Retinopathy
Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-dependent Diabetes Mellitus (IDDM)
There is evidence from a variety of animal studies that choroidal blood flow is under neural control. Recent results in humans indicate that a light/dark transition is associated with a short lasting reduction in choroidal blood…
- Trial name
- NCT00718614
- Testing
- Light will be switched from 0.5µW/cm2/sr to 115µW/cm2/sr.
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Urinary Retention, Urinary Bladder, Neurogenic
A Prospective Evaluation of the Catheter Science C3 "Umbrella Catheter."
The Catheter Science C3 "Umbrella Catheter" has been developed for management of urinary retention in patients who are either using a Foley or Self Intermittent Catheter.
- Conditions
- Urinary Retention, Urinary Bladder, Neurogenic, Intermittent Catheterization
- Trial name
- NCT03353571
- Testing
- C3 "UMBRELLA CATHETER"
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Gaines W. Hammond Jr. MD FACS
Fabry Disease
Open Label Extension of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Every 4 Weeks in Adult Fabry Disease Patients
The objective of CLI-06657AA1-03 (formerly PB-102-F51) is to evaluate the long-term safety, tolerability, and efficacy of 2 mg/kg pegunigalsidase alfa administered intravenously every four weeks in adult Fabry patients who have…
- Trial name
- NCT03614234
- Testing
- pegunigalsidase alfa
- Where
- 14 sites in United States, Belgium and 5 more
- Volunteers
- 29 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Analgesia, Donor Nephrectomy
PQLB vs TFPB in HALDN
This prospective randomized non-inferiority trial is designed to compare postoperative analgesic effect of transversalis fascia plane block and posterior quadratus lumborum block in hand assisted laparoscopic donor nephrectomy.
- Conditions
- Analgesia, Donor Nephrectomy, Postoperative Pain, Fascial Plane Block
- Trial name
- NCT07852663
- Testing
- Quadratus Lumborum Block type 2, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Koc University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.