Clinical trials: Neurologic Complication
Tonsillectomy
Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation
To Determine The Efficacy of a Rapid Bolus Injection of Dexmedetomidine on the Incidence of Emergence Agitation in Anesthetized Children and the Cardiovascular Profile of a Rapid Bolus Injection of Dexmedetomidine.
- Trial name
- NCT01528891
- Testing
- Dexmedetomidine
- Where
- 2 sites in United States
- Volunteers
- 418 people
- Sponsor
- Peter Davis
Pain, Postoperative
Role of Propolis Paste in Preventing Pain After Root Canal Treatment.
This study evaluates the role of propolis paste as compared to calcium hydroxide (when used as intracanal medication) in prevention and treatment of pain after root canal treatment in necrotic (infected) teeth.
- Trial name
- NCT03723980
- Testing
- Propolis, Calcium Hydroxide
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Juzer Shabbir Saifee
Postoperative Pain, Hernia
A Safety and Efficacy Study of SABER®-Bupivacaine for Pain Following Hernia Repair
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local…
- Conditions
- Postoperative Pain, Hernia, Surgery
- Trial name
- NCT00974350
- Testing
- SABER-Bupivacaine
- Where
- 5 sites in Australia, New Zealand
- Volunteers
- 124 people
- Sponsor
- Durect
Fractures, Bone, Nausea and Vomiting, Postoperative
Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration
The aim of this study is to evaluate not only the occurrence of side effects, but the quality of the recovery (QoR-40 Questionnaire) of patients submitted to spinal anesthesia with administration of low doses (0.1 mg) of…
- Conditions
- Fractures, Bone, Nausea and Vomiting, Postoperative, Pruritus, Morphine Adverse Reaction
- Trial name
- NCT03035942
- Testing
- Dexamethasone, Ondansetron, Saline
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Scheduled Cesarean Sections, Postoperative Pain Management
Low Pain Prediction in Cesarean Section Patients
The investigators are attempting to see if eliminating the amount of long acting spinal narcotic during cesarean section delivery will demonstrate pain scores with movement when evaluated 24 hours postoperatively as those that…
- Conditions
- Scheduled Cesarean Sections, Postoperative Pain Management, Side Effects
- Trial name
- NCT02143141
- Testing
- duramorph
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Neuropathy
A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy
This study is designed to examine how pregabalin affects parameters of autonomic nerve regulation in correlation with change in pain, anxiety, and depressive symptoms in patients with diabetic neuropathy.
- Trial name
- Pregabalin (NCT00573261)
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Postoperative Pain
Ultrasound Guided Distal Peripheral Nerve Blocks and Postoperative Pain.
The aim of this clinical trial is to determinate if distal ultrasound guided peripheral nerve blocks on target nerves (radial and median nerve blocks at the elbow), using low volume and low concentration of long acting local…
- Trial name
- NCT01597479
- Testing
- Levobupivacaine
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postoperative Pain, Obstetric Pain
Lidocaine Patches After Cesarean Section
The aim of this study is to investigate the impact of using lidocaine patches after cesarean section on pain control and opioid use in the immediate post-operative period.
- Conditions
- Postoperative Pain, Obstetric Pain, Opioid Use
- Trial name
- LPACS (NCT04443569)
- Testing
- Lidocaine patch
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Yale University
Abdominal Hernias and Other Abdominal Wall Conditions, Post-operative Pain
A Study to Evaluate Two Different Surgical Methods for Treatment for Abdominal Wall Diastasis
This is a three armed prospective randomized trial that will compare two different surgical techniques for reconstruction of the abdominal wall diastasis with a conservative treatment procedure.
- Conditions
- Abdominal Hernias and Other Abdominal Wall Conditions, Post-operative Pain, Recurrence
- Trial name
- NCT01586741
- Testing
- Quill suture application for repair or polypropylene mesh
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
Pain, Postoperative, Analgesia
Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
The aim of the study is to compare the efficacy of the pre-operative administration of Paracetamol and placebo in reducing postoperative pain after routine dental treatment in children.
- Trial name
- NCT02393339
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hysterectomy, Pain, Postoperative
B&O for TLH Post-operative Pain and Nausea
A prospective, single-center, double-blind, randomized, placebo-controlled trial to assess the impact of immediate post-operative placement of a Belladonna and Opium (B\&O) rectal suppository on postoperative pain and nausea…
- Trial name
- NCT03657407
- Testing
- Belladonna Opium, Glycerin Suppository
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Anna Reinert
Pain, Postoperative, Ankle Fractures
Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
The purpose of this study is to determine the efficacy and safety of a peri-articular multimodal injection for post-operative pain control following operative management of closed, rotational ankle fractures.
- Trial name
- NCT02967172
- Testing
- Ropivacaine, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Arthropathy of Hip
Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain have improved conditions in the postoperative period for patients undergoing total hip…
- Trial name
- NCT02493621
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Amputation, Phantom Limb
Naval Medical Center San Diego (NMCSD) - Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
The purpose of this research study is to determine if putting local anesthetic-or numbing medication-through one or two tiny tube(s) placed next to the nerves that go to an amputated limb will decrease phantom limb and/or stump…
- Conditions
- Amputation, Phantom Limb, Stump Pain
- Trial name
- NCT00768248
- Testing
- perineural ropivacaine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Diego
Surgery, Delirium
Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients
This study aims to assess the feasibility, acceptability, and safety of using ReCognitionVR virtual reality-based software in older surgical patients.
- Conditions
- Surgery, Delirium, Delirium, Post-Operative
- Trial name
- NCT06232317
- Testing
- Virtual Reality Software, Traditional Orientation Methods
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Methodist Hospital Research Institute
Autoimmune Diseases, Renal Disorders
Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device
This study will evaluate the use of the AMICUS device in patients where Therapeutic Plasma Exchange (TPE) is prescribed by their physicians.
- Conditions
- Autoimmune Diseases, Renal Disorders, Hematologic Disorders, Oncologic Disorders
- Trial name
- NCT01210716
- Testing
- Therapeutic plasma exchange
- Where
- 4 sites in United States
- Volunteers
- 37 people
- Sponsor
- Fenwal, Inc.
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea
The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation
The investigators aim to investigate the effect of dexmedetomidine on the perioperative respiratory complications in this patient population undergoing both awake and deep tracheal extubation.
- Conditions
- Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Tonsillitis, Adenoiditis
- Trial name
- NCT02162433
- Testing
- Normal Saline, Dexmedetomidine
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Pain, Postoperative, Postoperative Nausea and Vomiting
Efficacy Safety Score in Postoperative Management
The primary aim of this project is to determine whether postoperative patients may benefit from the Efficacy Safety Score (ESS) as a tool for postoperative clinical decision support, with a special focus on the first 24 hours…
- Trial name
- NCT03438578
- Testing
- Efficacy Safety Score monitoring
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Melanoma, Metastatic Malignant Neoplasm in the Spine
Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery
This pilot clinical trial studies adaptive staged stereotactic body radiation therapy (SBRT) in treating patients with spinal metastases that cannot be removed by surgery.
- Conditions
- Melanoma, Metastatic Malignant Neoplasm in the Spine, Renal Cell Carcinoma, Soft Tissue Sarcoma
- Trial name
- NCT02527304
- Testing
- Image-Guided Adaptive Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Albert Einstein College of Medicine
Pain, Postoperative Pain
A Comparative Study of JNS013 in Participants With Post-Tooth-Extraction Pain
The purpose of this study is to evaluate the efficacy and safety of JNS013 with single oral dose administration in participants with pain after tooth-extraction of mandibular impacted wisdom tooth.
- Trial name
- NCT00737048
- Testing
- Tramadol Hydrochloride, Acetaminophen, Tramadol plus Acetaminophen
- Where
- 11 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Janssen Pharmaceutical K.K.
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