Clinical trials: Neurologic Complication
Diabetic Neuropathy
Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy
The purpose of this protocol is to investigate the safety, tolerability and effectiveness of CAST as a treatment for diabetic neuropathy. The primary outcome measure will be Total Neuropathic Symptom Score.
- Trial name
- CAST (NCT00608439)
- Testing
- Centella asiatica selected triterpenes (CAST)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Oregon Health and Science University
Postoperative Pain, Cerebral Palsy
Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy
Popliteal block is a technique for providing postoperative pain management in children. In this randomized double-blinded study, the investigators evaluated the effects of preoperative popliteal nerve block on postoperative pain…
- Trial name
- NCT02507700
- Testing
- Popliteal block, Sevoflurane, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Acute Post Operative Pain
Improvement in Postoperative Pain Outcomes
This is an observational study project aims at improving postoperative pain outcomes by evaluating the current status of postoperative pain managements in the institution.
- Trial name
- NCT05624502
- Where
- Saudi Arabia
- Volunteers
- 1,000 people
- Sponsor
- King Saud University
Wolfram Syndrome
Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome
Open label, phase II study non randomized single group assignment of 20 evaluable patients 13 years and older, over 37,5 kg body-weight, with sensorineural hearing loss of at least 20 dB at 8 kHz in high frequency average (HFA)…
- Trial name
- AUDIOWOLF (NCT04940572)
- Testing
- Depakine
- Where
- 2 sites in France, Spain
- Volunteers
- 23 people
- Sponsor
- Centre d'Etude des Cellules Souches
Clavicle Fracture, Postoperative Pain
Effectiveness of Superficial Cervical and Clavipectoral Block for Clavicle Surgery
This study aims to compare two local anesthesia techniques (nerve blocks) for patients undergoing collarbone (clavicle) fracture surgery. Typically, this surgery uses the "Interscalene Block" (ISB) technique.
- Conditions
- Clavicle Fracture, Postoperative Pain, Regional Anesthesia Block
- Trial name
- BSS-BKvsBSS-BI (NCT07548775)
- Testing
- Combination of Superficial Cervical Block and Clavipectoral Block (SCB + CPB), Combination of Superficial Cervical Block and Interscalene Block (SCB + ISB)
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Udayana University
Post Operative Pain
Comparison of Exparel to Marcaine in Post-Surgical Analgesia in Bariatrics
This study is designed to evaluate the use of bupivacaine liposome 1.3% compared bupivacaine 0.5% in pain control in post-operative laparoscopic bariatric surgery patient The purpose of this study is to evaluate two local…
- Trial name
- NCT02752230
- Testing
- Laparoscopic Roux en Y gastric bypass, Laparoscopic Sleeve Gastrectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kettering Health Network
Liver Cirrhosis
Exploring the Mechanisms of Postoperative Delirium in Cirrhotic Patients Through Multi-Omics Integrative Analysis
This study looks at memory problems after surgery in people with liver disease. We want to know how often these problems happen and what might cause them. The main question it aims to answer is: 1.
- Trial name
- NCT07012434
- Volunteers
- 133 people
- Sponsor
- Sichuan Provincial People's Hospital
Rotator Cuff Injuries, Postoperative Pain
Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair
The goal of this clinical study is to learn if using a special pillow placed behind the shoulder can help to reduce pain and improve sleep for patients after surgery to repair a torn rotator cuff.
- Conditions
- Rotator Cuff Injuries, Postoperative Pain, Sleep Quality
- Trial name
- NCT07372222
- Testing
- Posterior Shoulder Pillow, Conventional Rehabilitation Protocol
- Volunteers
- 126 people
- Sponsor
- Peking University Third Hospital
Postoperative Pain Management, Postoperative Pain
Comparative Efficacy of Sciatic and Femoral Blocks in Ankle Surgery
Comparison of Anesthetic and Postoperative Analgesic Efficacy of Femoral and Popliteal Sciatic Block vs Femoral and Anterior Sciatic Block in Ankle Surgery
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- NCT06758245
- Testing
- femoral and anterior sciatic nerve block, femoral and popliteal sciatic nerve block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Pain
Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination on Postoperative Opioid Consumption
This prospective, randomized, double-blinded study is designed to evaluate the postoperative analgesic effect of the intravenous acetaminophen/ibuprofen fixed-dose combination in patients undergoing video-assisted thoracic…
- Trial name
- NCT05366777
- Testing
- acetaminophen/ibuprofen fixed-dose combination, Saline
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Hospital
Perinatal Listeriosis
Neurological Consequences of Perinatal Listeriosis Infection
The purpose of the study is to determine whether perinatal listeriosis is associated with long-term neurological consequences, and to evaluate the respective contribution of perinatal sepsis, of prematurity and of the known…
- Trial name
- MONALISABABY (NCT02580812)
- Testing
- Clinical and neuropsychological evaluation procedure
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adenomyosis, Infertility
Norwegian Adenomyosis Study III: Peristalsis
Spontaneous contractions (peristalsis) of the non-pregnant uterus is widely investigated and the role of correct peristalsis is most important for correct sperm transport towards the fallopian tubes and implantation of the…
- Conditions
- Adenomyosis, Infertility, Dysmenorrhea
- Trial name
- NAPPEDIII (NCT02197936)
- Where
- Norway
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Chronic Kidney Disease, Acute Bleeding
The Strategy to Prevent Hemorrhage Associated With Anticoagulation in Renal Disease Management (STOP HARM) Trial
Patients with severe chronic kidney disease (CKD) who develop atrial fibrillation are at high risk for stroke. The use of blood thinking medication in dialysis patients is controversial and warfarin carries a serious risk for…
- Conditions
- Chronic Kidney Disease, Acute Bleeding, Cerebrovascular Stroke
- Trial name
- STOP-HARM (NCT02885545)
- Testing
- Watchman, Continued therapy with the prescribed oral anticoagulant
- Where
- Canada
- Sponsor
- Population Health Research Institute
Postoperative Pain
Fentanyl 12 Mcg Transdermal Patch For Postoperative Pain
The investigators designed a prospective randomized study to investigate the effect of fentanyl 12 mcg transdermal patch on postoperative pain following unilateral, single-level laminectomy/discectomy.
- Trial name
- NCT03199157
- Testing
- Fentanyl transdermal patch
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Baskent University
Arthroplasty, Replacement
Effectiveness of Pulsed Radiofrequency of the Saphenous Nerve in the Management of Knee Arthroplasty Pain
Approximately 40% of patients undergoing total knee arthroplasty develop acute to moderate post operative pain. Furthermore 20-30% develop chronic post operative pain.
- Conditions
- Arthroplasty, Replacement, Knee, Pain
- Trial name
- NCT03450681
- Testing
- Pulsed radiofrequency of the saphenous nerve before knee replacement surgery, Mock incision
- Volunteers
- 111 people
- Sponsor
- Fundación Santa Fe de Bogota
Arthritis Knee, Pain, Postoperative
Exparel Use in Adductor Canal Block After Total Knee Arthroplasty
Exparel has been shown to have better pain control compared to previously used infiltration agents, including bupivacaine, while having a minor side effect profile.
- Conditions
- Arthritis Knee, Pain, Postoperative, Opioid Use
- Trial name
- NCT04910165
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Postoperative Pain
Intraoperative Magnesium Sulfate Administration During Orthotopic Liver Transplantation
The aim of study is to assess the effect of intraoperative use of magnesium sulfate in liver donating patients in reducing post-operative morphine requirements in early postoperative 24 hour in adult living liver donor.The…
- Trial name
- NCT03717467
- Testing
- isotonic saline, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Diabetic Neuropathies
Randomized Study of Intravenous Immunoglobulin (IVIg) in Patients With Subacute Proximal Diabetic Neuropathy
OBJECTIVES: I. Determine the effect of intravenous immunoglobulin on recovery time of patients with proximal diabetic neuropathy. II. Determine whether rate of response is dose dependent in these patients.
- Trial name
- NCT00004407
- Testing
- immune globulin
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Lumbar Spinal Stenosis
EuroPainClinics® Study II (Prospective Trial)
In this prospective multi-centre double-blind trial the effect of the epiduroscopy will be examined in (approximately 300) adult patients with low back pain pain caused by failed back surgery syndrome (FBSS).
- Trial name
- EPCSII (NCT02459392)
- Testing
- Epiduroscopy, Hyaluronic Acid, DepoMedrol
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- EPC Education s.r.o.
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
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