Clinical trials: Neurologic Complication
Urinary Incontinence, Urinary Incontinence, Urge
Prophylactic Analgesia for Bladder Botox Injections
The goal of this clinical trial is to learn more about using phenazopyridine (Pyridium) for pain control during bladder onabotulinumtoxinA ("botox") injections for surgical management of overactive bladder (OAB) for patients at…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Overactive Bladder
- Trial name
- NCT06514430
- Testing
- Phenazopyridine, 1% lidocaine with sodium bicarbonate
- Where
- United States
- Sponsor
- Montefiore Medical Center
Postoperative Delirium
Optimized Anesthesia to Reduce Incidence of Postoperative Delirium
The purpose of this study is to compare the difference of incidence of postoperative delirium between patients received general anesthesia guided by Bispectral index (BIS) and patients received general anesthesia using standard…
- Trial name
- NCT02133430
- Testing
- Bispectral index, as measured by a BIS processor
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Chiang Mai University
Breast Cancer Female, Pain, Postoperative
Analgesic Effect of Adding Thoracic Paravertebral Nerve Blocks to Modified PEC Block in Breast Cancer Surgery
To compare efficacy and safety of adding thoracic paravertebral nerve blocks to modified PEC block versus modified PEC block only in breast cancer surgery.
- Trial name
- NCT04056676
- Testing
- Thoracic paravertebral block under ultrasound guidance, Intraoperative modified PEC block, GA with ETT
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Post Operative Pain
Post Operative Pain in Modified Radical Mastectomy.
we will assess post operative pain after surgery of modified radical mastectomy at 12 and 24 hours post operatively on arm movement and on rest
- Trial name
- NCT04620720
- Testing
- capule gabapentin
- Where
- Pakistan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Endometriosis
A Long-Term Study to Evaluate the Safety of Asoprisnil in the Treatment of Women With Endometriosis From Study M01-398
The objective of this study is to determine the long-term safety of asoprisnil 5 mg for 12 months in women with endometriosis from study M01-398.
- Trial name
- NCT00160420
- Testing
- Asoprisnil
- Volunteers
- 73 people
- Sponsor
- Abbott
Fall, Multiple Sclerosis
Is the Severity of Urinary Disorders Related to Falls in People With Multiple Sclerosis
Falls are a common problem in people with multiple sclerosis (PwMS) and can lead to severe consequences (trauma, fear of falling, reduction of social activities).
- Conditions
- Fall, Multiple Sclerosis, Lower Urinary Tract Symptoms
- Trial name
- NCT04338646
- Testing
- Clinical tests
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Gérard Amarenco
Dysmenorrhea, Menstrual Pain
Vaginal Sildenafil for Primary Dysmenorrhea
This open-label, non-randomized mechanistic study will evaluate whether a single 100 mg vaginal sildenafil citrate suppository reduces uterine hypercontractility during menstruation in adults with moderate-to-severe dysmenorrhea.
- Conditions
- Dysmenorrhea, Menstrual Pain, Endometriosis, Uterine Fibroid
- Trial name
- SILDYS (NCT07508358)
- Testing
- Sildenafil citrate vaginal suppository
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kevin Hellman
Laparoscopic Myomectomy
A Retrospective Review Of Outcomes Following Laparoscopic Myomectomy
This will be a retrospective review of approximately 900 patients who have undergone laparoscopic myomectomy since 1999. patients will be contacted by phone and surveyed.
- Trial name
- retromyo (NCT00672750)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Advanced Gynecologic Surgery Institute
Postoperative Pain
Rectus Abdominis Muscle Parameters and Postoperative Opioid Consumption in Geriatric Patients
This prospective observational study aims to evaluate the relationship between ultrasound-derived rectus abdominis muscle thickness and thickening fraction and postoperative opioid consumption in geriatric patients undergoing…
- Trial name
- NCT07545824
- Testing
- Ultrasound-Guided Rectus Sheath Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istinye University
Geriatric Patient Care Improvement, Postoperative Delirium (POD)
The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population
This study will be conducted on patients aged 65 and older scheduled for surgery due to lumbar or cervical disc herniation. General anesthesia is routinely used for these types of surgeries in the hospital.
- Conditions
- Geriatric Patient Care Improvement, Postoperative Delirium (POD), Burst Suppression
- Trial name
- NCT06844279
- Testing
- Control Group: Standard Hemodynamic Monitoring, Processed Electroencephalogram (BIS Index), Processed Electroencephalogram (DSA Mode)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Aslıhan Güleç
Movement Disorders, Neurology
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications
This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years.
- Conditions
- Movement Disorders, Neurology, Parkinsons Disease
- Trial name
- NCT05539196
- Testing
- Exablate Pallidotomy, Unilateral
- Where
- 5 sites in United States, Japan
- Volunteers
- 60 people
- Sponsor
- InSightec
Endometriosis, Pelvic Pain
Medical Treatment of Endometriosis-Associated Pelvic Pain
The Specific Aim of this project is to compare the efficacy and cost-effectiveness of continuous oral contraceptives versus leuprolide/norethindrone in the treatment of endometriosis-associated chronic pelvic pain.
- Trial name
- NCT00229996
- Testing
- Oral Contraceptive, Depot-Leuprolide/Norethindrone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Facial Paralysis
Outcome of Facial Palsy Following Rehabilitation
Retrospective case series,the aim of this study is to assess the outcome and rate of complications in patients with facial palsy following rehabilitation, a retrospective study.
- Trial name
- NCT04215562
- Testing
- rehabilitation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- University of Alexandria
Mechanical Ventilation Complication, Brain Injuries
Mechanical Ventilation on Hippocampus
Ventilator-associated brain injury (VABI) frequently occurs in ICU patients. Although animal studies indicate the hippocampus as a key target of VABI, its relevance in human patients remains uncertain.
- Trial name
- NCT06480162
- Testing
- Mechanical ventilation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Sanbo Brain Hospital
Phantom Limb Pain
Treatment of Phantom Limb Pain by Intensive Visual Simulation Therapy
Phantom limb pain (PLP) is reported by as much as 80 % of patients following an amputation. There is increasing knowledge of the relation between PLP and maladaptive changes in brain cortical regions.
- Trial name
- NCT06483035
- Testing
- Intensive Visual Simulation (IVS), Usual Care (UC)
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Oslo Metropolitan University
Post-operative Pain
Does a Single Shot Femoral Nerve Block Alone Produce Appropriate Pain Relief?
The aim of this study is to compare the efficacy of the analgesic effect of the preoperative femoral nerve block alone versus combined femoral, sciatic, obturator and lateral femoral cutaneous nerve blocks in patients after TKA…
- Trial name
- NCT01303120
- Testing
- Femoral Nerve Block, Combined nerve blocks, Patient-controlled analgesia
- Where
- Israel
- Volunteers
- 107 people
- Sponsor
- Hillel Yaffe Medical Center
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hydrocephalus, Normal Pressure
Using Cerebrospinal Fluid Dynamics to Optimize Treatment of Idiopathic Normal Pressure Hydrocephalus
The purpose of the study is to determine if the so called pulsatility curve, which describes the relationship between intracranial pressure (ICP) and ICP pulsatility, can be used to predict outcome of treatment, in the form of…
- Trial name
- PULSE-OPT (NCT03076723)
- Testing
- Change in shunt opening pressure, Simulated change in shunt opening pressure
- Where
- 5 sites in Finland, Sweden
- Volunteers
- 43 people
- Sponsor
- Umeå University
Pain, Postoperative, Bariatric Surgery Candidate
A Study to Compare Two Techniques for Pain Control After Bariatric Surgery
The purpose of this study is to compare the postoperative pain and other clinical outcomes in patients who, during bariatric surgery, will be injected with a local anesthetic (Ropivacaine) through two different techniques.
- Trial name
- NCT04427059
- Testing
- Transversus Abdominis Plane (TAP) block, Port-Site Infiltration (PSI)
- Where
- Switzerland
- Volunteers
- 115 people
- Sponsor
- Fabio Garofalo
Angina Pectoris, Myocardial Infarction
GLP-1 Loading During Elective Percutaneous Coronary Intervention
Angina is caused by narrowings or blockages within coronary arteries. Coronary angioplasty and stenting is performed for people with angina to improve the blood supply to the heart by placing metal tubes within the artery using…
- Conditions
- Angina Pectoris, Myocardial Infarction, Reperfusion Injury, Coronary Heart Disease
- Trial name
- GOLD-PCI (NCT02127996)
- Testing
- GLP-1
- Where
- United Kingdom
- Volunteers
- 193 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
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