Clinical trials: Neurologic Complication
Postoperative Pain
Nalbuphine as an Adjuvant to Intravenous Regional Anesthesia
The effect of addition of nalbuphine to lidocaine in intravenous regional anesthesia
- Trial name
- NCT02678585
- Testing
- Nalbuphine, Lidocaine
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Assiut University
Neurogenic Urinary Bladder, Spastic
Bilateral vs. Unilateral Stimulation in Neurological Bladder Disroders
This study evaluates the effectiveness of bilateral stimulation of the tibial nerve compared to unilateral stimulation in neurological bladder disorders.
- Trial name
- UROSTIM (NCT04225143)
- Testing
- urostim bilateral, urostim unilateral
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Acute Kidney Injury, Hypoxia-Ischemia, Brain
Tissue Oxygenation During Treatment of Infant Congenital Heart Defects
Background: Acute kidney injury (AKI) is a common and serious postoperative complication in children with congenital heart disease.
- Conditions
- Acute Kidney Injury, Hypoxia-Ischemia, Brain, Mesenteric Ischemia
- Trial name
- NCT03941015
- Where
- China
- Volunteers
- 245 people
- Sponsor
- Beijing Anzhen Hospital
Microvascular Disease, Microvascular Complications
Comparison of Differencens in VO2-max, Perfusion of the Heart and Brain and Cognitive Performance Between Patients with Type 2 Diabetes and Healthy Age Matched Controls.
In the aging population, ischemic heart disease, stroke and dementia are increasingly prevalent. Diagnosis and treatment of the former two i.e., large-vessel coronary heart disease and endovascular thrombectomy of the brain in…
- Conditions
- Microvascular Disease, Microvascular Complications, Dementia, Diabetes Mellitus Type 2
- Trial name
- SVAT (NCT06628297)
- Testing
- PET
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Male Breast Cancer, Stage IV Breast Cancer
Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer
This phase I trial is studying the side effects and best dose of cediranib maleate when given together with whole brain radiation therapy in treating patients with brain metastases from non-small cell lung cancer.
- Conditions
- Male Breast Cancer, Stage IV Breast Cancer, Stage IV Melanoma, Stage IV Non-small Cell Lung Cancer
- Trial name
- NCT00937482
- Testing
- cediranib maleate, whole-brain radiation therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Cancer Institute (NCI)
Parkinson Disease
DESENSITIZE-PD: Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Support Dopaminergic Desensitization in PD
20 patients with idiopathic Parkinson's disease, who are planned to undergo intestinal L-Dopa + entacapone (Lecigon®) treatment will be included into this observational single-armed study.
- Trial name
- NCT05579379
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Elderly, Orthopedic Surgery
Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery
Delirium is common in the elderly after orthopedic surgery and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after orthopedic surgery, dexmedetomidine supplemented intravenous…
- Conditions
- Elderly, Orthopedic Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03629262
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 712 people
- Sponsor
- Peking University First Hospital
Hernia, Inguinal, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Surgical intervention to treat a inguinal hernia is a very common pediatric surgical procedure, often performed using an inguinal incision.
- Trial name
- NCT03041948
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- 2 sites in Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Low Anterior Resection Syndrome, Rectal Cancer
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)
The preservation surgery of the anal sphincter muscle has become the standard procedure in the treatment of rectal cancer and, thanks to advancements in surgical techniques, can now be performed for tumors located closer to the…
- Conditions
- Low Anterior Resection Syndrome, Rectal Cancer, Insomnia, Sleep Disorder
- Trial name
- TraLARS (NCT06222255)
- Testing
- Transanal Irrigation (TAI)
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain
The Effect of Bilateral Rectus Sheath Block Versus Wound Infiltration in Gynecooncological Patients
Postoperative pain is a serious problem in gynecological oncology patients who underwent median vertical incision. The aim of our study is to compare ultrasound guided bilateral rectus sheath block and local anesthetic wound…
- Trial name
- NCT06095908
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Knee Osteoarthritis, Persistent Postsurgical Pain
Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain
Chronic knee pain remains a disabling disease despite current treatment strategies. There is an increase in the prevalence of osteoarthritis (OA) of the knee in the general population, presently affecting approximately 450,000…
- Conditions
- Knee Osteoarthritis, Persistent Postsurgical Pain, Chronic Knee Pain
- Trial name
- COGENIUS (NCT05407610)
- Testing
- Conventional Radiofrequency ablation of the genicular nerves, Cooled Radiofrequency ablation of the genicular nerves
- Where
- 15 sites in Belgium, Netherlands
- Volunteers
- 400 people
- Sponsor
- Ziekenhuis Oost-Limburg
Postoperative Pain
EXORA vs ESP Blocks in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is still considered the gold standard for the surgical management of gallbladder disease due to its minimally invasive nature, shorter recovery time, and reduced postoperative complications.
- Trial name
- NCT07187310
- Testing
- EXORA block, Erector Spinae Plane block
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Fayoum University Hospital
Post Operative Pain
Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia
It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries.
- Trial name
- NCT05338320
- Testing
- Ultrasound Guided Erector Spinae Plane Block, Intrathecal morphine, General anesthesia using intravenous fentanyl (1µg/kg)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Intraventricular Neoplasm
Observational Pilot Study With TachoSil as a Ventricular Sealant
The working hypothesis in this study is that after entering the cerebral ventricular system the sealing with TachoSil is effective and safe.
- Trial name
- NCT05717335
- Testing
- TachoSil
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Germans Trias i Pujol Hospital
Anxiety, Pain
Text Message Study
The objectives of this double-blind, randomized, controlled study are to evaluate the efficacy of maintaining contact with low-back pain patients through text messaging and emailing, to decrease anxiety levels, pain, number of…
- Conditions
- Anxiety, Pain, Surgical Site Infection
- Trial name
- NCT01789697
- Testing
- cellular device/computers
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Diabetic Retinopathy, Diabetes Mellitus, Type 2
Confronting Unequal Eye Care in Pennsylvania
Pt. 1 Diabetic retinopathy is a common eye condition among diabetic adults and can lead to severe vision impairment and even blindness.
- Conditions
- Diabetic Retinopathy, Diabetes Mellitus, Type 2, Glaucoma
- Trial name
- NCT01179555
- Testing
- Behavioral Activation, Supportive Therapy
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wills Eye
Knee Osteoarthritis, Pain, Postoperative
NOCTURNAL PAIN After Knee Arthroplasty : Incidence and Risk Factor: an Observational Study
In prosthetic knee surgery, there is a certain number of patients with post-operative nocturnal pain. The purpose of our study is to determine the impact of this problem and to better understand its risk factors.
- Conditions
- Knee Osteoarthritis, Pain, Postoperative, Prosthesis (Internal) Complications, Nocturnal Frequency
- Trial name
- NOCTURN-PAIN (NCT03998943)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Postanesthetic Excitement, Cesarean Section
Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean…
- Trial name
- NCT06289335
- Testing
- saline solution
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dialysis; Complications
Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Serum Magnesium Levels
Individuals with ESKD and treated with hemodialysis have a high mortality risk. Associative studies suggest a relationship between serum magnesium concentration and mortality risk.
- Trial name
- OMAGOD-1 (NCT07565779)
- Testing
- A - Dialysate magnesium 0.75, B - Dialysate magnesium 1.00 mmol/L
- Where
- 4 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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