Clinical trials: Neurologic Complication
Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy
ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy
This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic…
- Trial name
- ESP TAP (NCT07661693)
- Testing
- Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziantep City Hospital
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Diabetic Foot Ulcer, Diabetic Wound
Peer Support for Patients With Diabetic Foot Ulcers
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation…
- Conditions
- Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot
- Trial name
- NCT06004219
- Testing
- Peer counseling group
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Pain, Dyspareunia
Randomized Trial of Interrupted Versus Continuous Vaginal Closure of Anterior Repair With Mesh
Vaginal prolapse is a common condition that is treated with surgical correction. Recently surgeons have been using mesh to augment the repair of vaginal prolapse.
- Conditions
- Pain, Dyspareunia, Surgical Mesh
- Trial name
- NCT00676000
- Testing
- Interrupted vaginal closure, Continuous vaginal closure
- Volunteers
- 350 people
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain
Lumbar Erector Spinae Plane Block and Quadratus Lumborum Block in Hip and Proximal Femur Surgeries
Multimodal analgesia is used to control postoperative pain in hip surgery. Quadratus lumborum block is an effective regional anesthesia technique for hip and proximal femur surgery.
- Trial name
- NCT03508544
- Testing
- Lumbar ESP block, QLB bLock, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Painful Diabetic Neuropathy
Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression
The UT Southwestern Medical Center at Dallas would like to give you information about a research study that is being done for patients with painful diabetic neuropathy and have not responded to medical treatment.
- Trial name
- DNND (NCT00703209)
- Testing
- Nerve Decompression
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Respiratory Depression
Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical Pain
To meet the unmet need of better and safer pain relief for acute pain in the post-operative setting, a Vital-signs-integrated Patient-assisted Intravenous opioid Analgesia ("VPIA") Delivery System, with novel and intelligent…
- Trial name
- VPIA (NCT04011163)
- Testing
- VPIA pump, Morphine
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Postoperative Pain
Analgesia Nociception Index in Orthognathic Surgery
This study aims to determine whether goal-directed analgesia using ANI(Analgesia/Nociception Index) can improve the quality of postoperative recovery in patients undergoing maxillofacial surgery.
- Trial name
- NCT06205355
- Testing
- Analgesia/Nociception Index (ANI) monitoring, Standard monitoring
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Mild Cognitive Impairment (MCI), Opioid Use
Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment
Mild cognitive impairment (MCI) affects a substantial proportion of older adults undergoing major surgery and may alter pain processing, pain experience, and opioid use after surgery.
- Conditions
- Mild Cognitive Impairment (MCI), Opioid Use, Cognitive Dysfunction, Postoperative Pain
- Trial name
- NCT07885085
- Where
- United States
- Volunteers
- 552 people
- Sponsor
- Miklos Kertai
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Post-operative Pain, Post-operative Nausea and Vomiting
Multimodal Perioperative Pain Management: ComfortSafe Program
Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical…
- Conditions
- Post-operative Pain, Post-operative Nausea and Vomiting, Respiratory Depression, Confusion Postoperative
- Trial name
- NCT04046068
- Testing
- ComfortSafe Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
End-Stage Kidney Disease, Chronic Kidney Failure
Animal Assisted Intervention for Hemodialysis Outpatients
The goal of this clinical trial is to understand if and how an animal-assisted intervention [AAI] using therapy dogs can support hemodialysis [HD] patients' treatment adherence and enhance their well-being.
- Conditions
- End-Stage Kidney Disease, Chronic Kidney Failure, Chronic Pain
- Trial name
- NCT06030050
- Testing
- Animal-assisted intervention
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Postoperative Pain
Elective Total Abdominal Hysterectomy With Preoperative Analgesia Intravenous Paracetamol Versus Placebo
The study aim to study to evaluate whether IV paracetamol reduces morphine use after TAH. Primary objective was to compare postoperative morphine consumption between the IV paracetamol and control groups.
- Trial name
- NCT07368790
- Testing
- Paracetamol
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Pain, Postoperative
Analgesic Efficacy of Bilateral US Guided TTPB vs ESPB in Pediatric Patients Undergoing Corrective Cardiac Surgeries
Corrective cardiac surgeries include a bundle of major surgeries that take place in pediatric patients and require imperative perioperative pain control; hence, the art of healing starts from trying to diminish or abolish pain.
- Trial name
- NCT05559684
- Testing
- Erector spinae plane block, Transversus thoracis plane block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Postoperative Pain, Acute, Hemodynamics
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients
In total knee arthroplasty (TKA), the use of a tourniquet and controlled hypotension is common. However, ischemia-reperfusion injury induced by the tourniquet and inappropriate controlled hypotension can lead to cardiac and…
- Conditions
- Postoperative Pain, Acute, Hemodynamics, Total Knee Arthroplasty (TKA)
- Trial name
- TKA (NCT07271849)
- Testing
- Nalbuphine Hydrochloride injection was administered during anesthesia induction., Nalbuphine Hydrochloride injection was administered after cement implantation., Standard general anesthesia regimen ( nalbuphine was not administered throughout the entire anesthesia process.)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Qianfoshan Hospital
Surgical Incision, Pain, Postoperative
Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision
Open gynecologic surgery can be very painful. With the goal of minimizing the use of opioids (with undesired side effects and potential for abuse), the investigators often administer a type of peripheral nerve block in which the…
- Conditions
- Surgical Incision, Pain, Postoperative, Pain, Acute
- Trial name
- NCT05082155
- Testing
- Bupivacaine 0.25%, Normal Saline
- Where
- United States
- Sponsor
- University of California, San Diego
Postoperative Pain
Interscalene Versus Combined Infraclavicular-suprascapular Nerve Blocks
The aim of this trial is to compare the analgesic efficiency and hemi-diaphragmatic paralysis of the standard ultrasound-guided interscalene (ISB) brachial plexus block with the combined use of costoclavicular approach of…
- Trial name
- NCT03628950
- Testing
- ICSSB group, ISB group
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Fayoum University Hospital
Chronic Pain, Chronic Pelvic Pain Syndrome
BTA vs Baclofen for Pelvic Myofascial Pain Syndrome
The aim of the study is to test the hypothesis that oral taking of baclofen in therapeutic dosage for 60 days is equally effective as injection of botulinum toxin type "A" in the area of trigger points of the pelvic muscles.
- Conditions
- Chronic Pain, Chronic Pelvic Pain Syndrome, Myofascial Pain Syndrome, Myofascial Trigger Point Pain
- Trial name
- BvsB (NCT05617118)
- Testing
- Baclofen 10mg, Botulinum toxin type A
- Where
- Russia
- Volunteers
- 52 people
- Sponsor
- Saint Petersburg State University, Russia
Failed Back Surgery Syndrome
Value of Target-controlled Intravenous Anaesthesia (TCIVA) in Spinal Cord Stimulation
Study design 60 patients Monocenter prospective study Randomized in 2 groups 36 months Objectives Demonstrate the superiority of target controlled intravenous anesthesia versus total anesthesia with the low back paresthesia…
- Trial name
- AIVOC (NCT02821897)
- Testing
- Target-controlled intravenous anaesthesia, Total anaesthesia
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Poitiers University Hospital
Weight, Birth, Premature Birth
Effects of Olfactory and Gustatory Stimulus on the Nutrition of Premature Babies
The objective of this clinical trial is to test the effects of olfactory and taste stimulation with milk or water in premature newborns with a gestational age between 28 and 32 weeks.
- Trial name
- NCT06305052
- Testing
- Milk, Water
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
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