Clinical trials: Neurologic Complication
Nociceptive Pain, Pain, Postoperative
Guiding Opioid Administration in Patients With Regional Anesthesia
General anesthesia is a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception.
- Conditions
- Nociceptive Pain, Pain, Postoperative, Analgesia, Anesthesia Recovery Period
- Trial name
- GORA (NCT06040307)
- Testing
- SPI (Surgical Pleth Index)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Pain, Thoracic Surgery, Video Assisted
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
This prospective randomized controlled trial was conducted to compare the effectiveness of two ultrasound-guided regional anesthesia techniques, erector spinae plane block (ESPB) and serratus posterior superior intercostal plane…
- Trial name
- NCT07426692
- Testing
- Erector Spinae Plane Block (ESPB) group, Serratus posterior superior intercostal plane block, Morfin
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Marmara University
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postoperative Pain
Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia
Morphine is usually used for pain relief after cesarean delivery. However, sometimes it is not available, the patient might be allergic to morphine or intolerant to its side effects.
- Trial name
- NCT03592992
- Testing
- Spinal Hydromorphone, Spinal Morphine
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post Operative Pain
Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block vs Erector Spinae Plane Block in Open Nephrectomy
Our aim is to measure the efficacy of rhomboid intercostal subserratus plane block and erector spinae plane block in patients undergoing open nephrectomy
- Trial name
- NCT05822011
- Testing
- Rhomboid intercostal subserratus plane block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Vulvodynia, Vulvar Vestibulitis
Acupuncture for the Treatment of Vulvodynia
A randomized controlled pilot study was conducted to evaluate the effect of an acupuncture protocol for the treatment of vulvodynia. Hypotheses: 1. Acupuncture reduces vulvar pain and dyspareunia in women with vulvodynia. 2.
- Conditions
- Vulvodynia, Vulvar Vestibulitis, Pain, Dyspareunia
- Trial name
- NCT02197429
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Schlaeger, Judith M., CNM, LAc, PhD
Post Operative Pain
Postoperative Pain After Pulpectomy of Primary Molars Using Different Obturation Materials
Testing postopertive pain after pulpectomy of primary molars with Metapex and Endoflas using modified Wong-Baker scale of pain.
- Trial name
- NCT05475795
- Testing
- Metapex, Endoflas
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Minia University
Postoperative Pain, Chronic Pain
The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients
Patients with a daily use of opioids may develop higher postoperative pain levels, often need high doses of morphine and therefore their pain may be difficult to treat.
- Conditions
- Postoperative Pain, Chronic Pain, Analgesics
- Trial name
- NCT02085577
- Testing
- (S)-(+)-Ketamine Hydrochloride Solution 25 mg/ml, Isotonic sodium chloride 0.9 percent, Paracetamol 1 g
- Where
- Denmark
- Volunteers
- 147 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative
Dexmedetomidine for Improved Pain Relief and Recovery in Spine Surgery
Chronic low back pain (CLBP) is a prevalent condition causing significant pain, disability, and reduced quality of life. While various treatments like exercise, NSAIDs, and spinal manipulation are recommended, their effectiveness…
- Trial name
- NCT06685081
- Testing
- Dexmedetomidine, lidocaine and triamcinolone
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia University
Laryngeal Injury, Hoarseness
Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
The goal of this randomized clinical trial is to compare two different orotracheal tubes in patients which require orotracheal intubation for general anesthesia.
- Conditions
- Laryngeal Injury, Hoarseness, Cough, Sore-throat
- Trial name
- Triglotix® (NCT06108271)
- Testing
- Triglotix®, Conventional endotracheal tube
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Post Operative Pain, Acute
Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative Analgesia
Pregabalin is a structural analogue of gamma amino butyric acid (GABA). It binds to presynaptic alpha-2-delta subunit of voltage gated calcium channels in the brain and the spinal cord.
- Trial name
- NCT05150795
- Testing
- Pregabalin 150mg, Fentanyl 100 micrograms ampoule
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Breast Neoplasms, Pain, Postoperative
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic, Post-Mastectomy Chronic Pain Syndrome
- Trial name
- USB22 (NCT05494281)
- Testing
- Serratus Anterior Plane Block with local anesthetic, Serratus Anterior Plane Block with saline solution
- Where
- Morocco
- Volunteers
- 94 people
- Sponsor
- Moroccan Society of Surgery
Osteoarthritis, Knee
Functional Outcome and Analgesia in TKA: Radiofrequency vs Continuous Adductor Canal Block
This randomized, double blind controlled trial is designed to investigate the potential benefits of radiofrequency in terms of analgesia and functional outcome, compared to the conventional continuous adductor canal block, for…
- Trial name
- NCT02680392
- Testing
- Pulsed and Continuous Radiofrequency, Continuous Adductor Canal Block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Delayed Emergence From Anesthesia, Delirium, Cause Unknown
Inadequate Emergence After Laparoscopic Surgery in Trendelemburg Position
The purpose of this study is to determinate if the patients submitted to laparoscopic surgery in trendelemburg position develope more inadequate anaesthesic emergence than patients submitted to laparoscopic surgery in other…
- Conditions
- Delayed Emergence From Anesthesia, Delirium, Cause Unknown, Confusion, Disorientation on Emergence
- Trial name
- NCT02101671
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Corporacion Parc Tauli
Optic Nerve Sheath Neoplasm, Intracranial Pressure Increase
Optic Nerve Sheath Diameter in Pediatric Patients
Endotracheal intubation and laryngeal mask are generally applied to secure the airway during general anesthesia. There is a widespread opinion among anesthesiologists that endotracheal intubation increases intracranial pressure.
- Conditions
- Optic Nerve Sheath Neoplasm, Intracranial Pressure Increase, Intubation Complication, Airway Complication of Anesthesia
- Trial name
- NCT05445271
- Testing
- Optic nerve sheath diameter measurement with linear ultrasound
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
PreTerm Neonate
Effect of Nursing Interventions on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns
Babies born before the thirty-seventh gestational week are called preterm or premature. Most preterm newborns require Neonatal Intensive Care Unit (NICU) care depending on their gestational age and clinical condition.
- Trial name
- NCT06628232
- Testing
- pacifier with breast milk, heel heating, interventions combined
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Obesity, Myelomeningocele
Extended Criteria For Fetal Myelomeningocele Repair
The purpose of this study is to offer pre-natal Myelomeningocele (MMC) repair surgery to pregnant women with one of the former surgery exclusion factors A BMI of 35-40 kg/m2 Diabetes; patients will require good glycemic control…
- Conditions
- Obesity, Myelomeningocele, Pregnancy, Diabetes Mellitus in Pregnancy
- Trial name
- NCT02664207
- Testing
- Open Fetal Repair of Myelomeningocele
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Postoperative, Opioid Overdose
Ultrasound-guided PENG Block in Total Hip Replacement
This randomized controlled study will be carried out on 60 adult patients undergoing primary total hip replacement in Tanta University Hospitals.
- Trial name
- NCT04984109
- Testing
- Real PENG block
- Where
- Egypt
- Volunteers
- 71 people
- Sponsor
- Tanta University
Pain, Postoperative, Wound; Abdomen
Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters
This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.
- Conditions
- Pain, Postoperative, Wound; Abdomen, Incision
- Trial name
- SPARC (NCT03137732)
- Testing
- Rectus Sheath Catheter
- Volunteers
- 50 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Acute Mesenteric Ischemia
Analysis of the Acute Mesenteric Ischemia in a Single Institution Over 10 Years
Acute mesenteric ischemia (AMI) is a notorious disease with a high mortality, the diagnostic and management is truly multidisciplinary, but it is not the reality in many Hospitals.
- Trial name
- AMI_HMAR (NCT06310395)
- Volunteers
- 100 people
- Sponsor
- Hospital del Mar
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