Clinical trials: Neurologic Findings
Pituitary Tumor, Cerebrospinal Fluid Leakage
Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage
The papers propose a new method to prevent postoperative cerebrospinal fluid leakage. Doctors use the absorbable polyglycolic acid (PGA) and fibrin glue to repair in surgery, prevent cerebrospinal fluid leakage and reduce the…
- Trial name
- NCT06472505
- Testing
- polyglycolic acid(Neoveil)
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Miscarriage
Virtual Reality in MVA for Miscarriage
We are investigating the use of a virtual reality programme to reduce pain and anxiety experienced during manual vacuum aspiration.
- Trial name
- NCT04466956
- Testing
- Virtual reality
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Trisiomy 21 (Down Syndrome)
Vitamins and Minerals for Children With Downs Syndrome
The trial aimed to examine the effects of supplementation with antioxidants and folinic acid on the health, growth and psychomotor development of children with Down syndrome.
- Trial name
- NCT00378456
- Testing
- Antioxidants- (Vitamins A,C,E Selenium and Zinc), Folinic acid, Vitamins A,C,E Selenium and Zinc and Folinic acid.
- Where
- 3 sites in United Kingdom
- Sponsor
- Institute of Child Health
Mild Cognitive Impairment (MCI)
Enhancing Attention in Elderly Using a Brain-Computer-Interface
Cognitive reserve refers to the brain's ability to maintain cognitive performance despite age-related changes or neuropathology.
- Trial name
- NCT07441122
- Testing
- transcranial electrical stimulation, Mindfulness Meditation
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Pain During Colonoscopy
Improving Quality of Colonoscopy Using a 3D-imager
Coloscopy may be a painful procedure for the patient. This is due to a loop-formation of the coloscope. A 3D-real time imager produced by Olympus creates a real-time image of the scope while a traditional fluoroscopy device will…
- Trial name
- NCT00519129
- Testing
- 3D-imager
- Where
- Norway
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Pain, Muscle Rigidity
Investigation on a Topical Cosmetic Pain Lotion (Egyfil) for Stiffness and Pain Relief
The application of a novel topical formulation for the treatment of muscular pain and stiffness (Egyfil), containing hyaluronic acid, SH-Polypeptide-6 and SH-Oligopeptide-1, is investigated to evaluate efficacy and safety in 26…
- Trial name
- NCT05711953
- Testing
- Egyfil Pain Lotion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Contrad Swiss SA
Osteoarthritic Knee Pain
Freedom-1 Study for Chronic Knee Pain
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation.
- Trial name
- NCT03877653
- Testing
- Wireless neuromodulation
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Curonix LLC
Cesarean Section Complications
Cesarean Neuro Linguistic Programming Comfort
The aim of this study is to examine the effect of NLP techniques on stoma compliance and quality of life in patients with stoma.
- Trial name
- NCT05646537
- Testing
- Neuro-Linguistic Programming Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Toros University
Dysmenorrhea
Assessment of a Vaginal Ring With Meloxicam in the Treatment of Dysmenorrhea
The investigators propose that the sustained administration of a vaginal ring would have a better response with respect to pain and a better safety profile than the oral administration of a non-steroidal anti-inflammatory drug.
- Trial name
- NCT02255045
- Testing
- Meloxicam, Diclofenac Potassium
- Where
- Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Delirium, Cognitive Impairment
Cholinesterase Activity and DeliriUm During Critical Illness Study
Delirium is a syndrome of acute brain dysfunction involving attention and cognition that affects up to half of older hospitalized patients and 50%-75% of critically ill ICU patients, such that millions of patients worldwide…
- Trial name
- CADUCeuS (NCT03098472)
- Where
- United States
- Volunteers
- 279 people
- Sponsor
- Vanderbilt University Medical Center
Stroke, Proprioceptive Disorders
Combined Effects of PNF and Electrical Muscle Stimulation on Spasticity and Hand Function in Stroke Patients.
To determine the combined effects of proprioceptive neuromuscular facilitation and electrical muscle stimulation on spasticity and hand function in stroke patients.
- Conditions
- Stroke, Proprioceptive Disorders, Balance; Distorted
- Trial name
- NCT05916872
- Testing
- experimental group, control group
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Chronic Pain, Chronic Insomnia
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT06345872
- Testing
- CBT-I, Treatment as usual, Tapered Withdrawal
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pain
Stimulating Catheter With or Without Ultrasound Guidance
To study whether the combination of ultrasound guidance and stimulating catheter could reduce the time for needle and catheter insertion compared with using stimulating catheter alone.
- Trial name
- NCT00980577
- Testing
- NUUS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Mechanical Low Back Pain
Mobile App-Supported Exercise Program For Mechanical Low Back Pain
Mechanical low back pain is one of the most common musculoskeletal disorders affecting daily activities and quality of life. Home exercise programs are frequently recommended in the management of low back pain; however, adherence…
- Trial name
- NCT07495475
- Testing
- Mobile Application-Supported Home Exercise Program, Printed Home Exercise Program
- Volunteers
- 50 people
- Sponsor
- Karabuk University
Low Back Pain
Thera-Band® HEP for LBP Secondary Prevention
The purpose of this study is to determine the effectiveness of a Thera-Band based home exercise program (HEP) on LBP and disability 4 weeks post treatment discharge.
- Trial name
- TBKT_HEP (NCT02355275)
- Testing
- Home Exercise Program
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Agitation
Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine
Emergence agitation (EA) is common after nasal surgery under general anesthesia, which can lead to several problems, such as increased risk of injury to the patient or medical staff, pain, decreased patient satisfaction…
- Trial name
- NCT04908605
- Testing
- Mirtazapine, Melatonin
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Ain Shams University
Chronic Pain, Back Pain
Hippocampal Stimulation in Chronic Low Back Pain
In this study the investigators aim to examine the effects of Transcranial Magnetic Stimulation (TMS) on hippocampal network connectivity and pain levels in individuals with chronic low back pain.
- Conditions
- Chronic Pain, Back Pain, Pain
- Trial name
- NCT04888494
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwestern University
Brain Injury, Muscle Weakness
A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial
Intensive care unit (ICU) hospitalization saves lives but often does so at a high personal cost to ICU survivors who frequently experience significant cognitive impairment and an array of physical and functional disabilities that…
- Trial name
- RETURN (NCT00715494)
- Testing
- Cognitive, physical, and functional rehabilitation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University
Moderate to Severe Acute Lower Back Pain
Safety and Efficacy of SP-103 in Subjects With Moderate to Severe Acute Lower Back Pain
This is a Phase 2, randomized, double-blind, placebo-controlled, parallel group, multicenter study to evaluate the safety and efficacy of SP-103 in subjects with moderate to severe acute lower back pain.
- Trial name
- NCT05096494
- Testing
- SP-103
- Where
- 10 sites in United States
- Volunteers
- 76 people
- Sponsor
- Scilex Pharmaceuticals, Inc.
Low Back Pain, Transcranial Direct Current Stimulation
Transcranial Direct Current Stimulation Combined With Exercise in Low Back Pain
The purpose of this study is to evaluate the effects of transcranial direct current stimulation combined with Pilates based exercise on chronic low back pain. This is a randomized clinical trial composed of two arms.
- Trial name
- NCT05467566
- Testing
- Transcranial direct current stimulation
- Volunteers
- 42 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
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