Clinical trials: Neurologic Findings
Sleep Initiation and Maintenance Disorders
Combined Behavioral/Pharmacological Therapy for Insomnia
This study will determine how sleeping pills can be combined with nondrug treatments to maximize the benefits of therapy for insomnia.
- Trial name
- NCT00044629
- Testing
- Cognitive-Behavioral Therapy for Insomnia, zolpidem tartrate (Ambien)
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Duke University
Pregnancy, Unwanted
Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial
Despite global efforts to decrease discomfort during surgical abortion, pain remains a limiting factor in where and how procedures are performed.
- Trial name
- SALSA (NCT02447029)
- Testing
- vaginal 2% Xylocaine, standard lidocaine paracervical block
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Stanford University
Procedural Pain, Procedural Anxiety
Pain Elimination and Anxiety Control Through Experiential Virtual Reality
The goal of this clinical trial is to determine if active virtual reality is more effective than passive virtual reality and standard of care distraction in decreasing pain in children, from 8 to 21 years old, undergoing…
- Trial name
- NCT06504602
- Testing
- Active Virtual Reality, Passive Virtual Reality
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Stroke, Arm
Enhancing Recovery of Arm Movement in Stroke Patients
Many people who have had a stroke have problems recovering the use of their affected arm and these problems may persist for a long time.
- Conditions
- Stroke, Arm, Paresis
- Trial name
- ENHANCE (NCT02725853)
- Testing
- tDCS, personalized practice, non-personalized practice
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University
Post-operative Pain
Genetics of Cytochrome CYP2D6 and Effects of Codeine and Tramadol on Postoperative Pain Management
Codeine is one of the most commonly prescribed opioids in the world. The speed at which our liver metabolizes codeine into morphine depends on an important protein called cytochrome P450 2D6 (CYP2D6).
- Trial name
- CYP2D6 (NCT06723379)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fraser Health
Chronic Pain, Musculoskeletal Pain Disorder
Cognitive Bias Modification for Interpretation Individuals With Chronic Musculoskeletal Pain
Cognitive Bias Modification for Interpretation (CBM-I) trains participants to interpret ambiguous information as neutral or benign, rather than interpret it as being related to pain.
- Trial name
- NCT06368362
- Testing
- Benign cognitive bias modification for interpretation, Pain-related cognitive bias modification for interpretation
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Pain, Postoperative, Lung Cancer
Postoperative Pain Control With Lipossomic Extended Release Bupivacaine
Randomized trial of intraoperative intercostal block with bupivacaine with epinephrine compared to lipossomal extended release bupivacaine.
- Trial name
- NCT03560362
- Testing
- Bupivacaine liposome, Bupivacaine / Epinephrine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Tennessee
Chest Pain, Anxiety
The Effects of Use of Auditory Stimulation Methods on Cardiac Patients' Clinical Outcomes
This study will be used to compare the effects of two auditory stimulation methods on improving vital signs parameters, reducing the severity of chest pain, and improving the sleep quality of cardiac patients.
- Conditions
- Chest Pain, Anxiety, Sleep
- Trial name
- NCT06670027
- Testing
- Family voice, Nature sound
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Post Operative Pain, Stress Response
Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response
Inguinal hernia surgery is the most common practice of pediatric surgeons in their clinical practice. As these operations are usually day case procedures, maintaining adequate analgesia is an important component of perioperative…
- Conditions
- Post Operative Pain, Stress Response, Erector Spinae Plane Block, Caudal Block
- Trial name
- NCT05633173
- Testing
- Ultrasound-guided erector spinae plan block, Ultrasound-guided caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Anxiety, Surgery
Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?
Background: Anxiety is a common phenomenon in hospitalized patients. In order to reduce it during the surgical procedure, sedatives and anxiolytics are used, which can cause undesirable side effects for patients.
- Conditions
- Anxiety, Surgery, Drug Toxicity, Anesthesia
- Trial name
- NCT03882541
- Testing
- Music therapy, Sedation with midazolam
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de l'Anoia
Pruritis
Nalbuphine for the Treatment of Opioid Induced Pruritus in Children
Itching is a frequent and disturbing side effect of the use of pain medication such as morphine. In the post-operative period, it can be more distressing to pediatric patients than their pain.
- Trial name
- NCT00323154
- Testing
- Nalbuphine
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- University of British Columbia
Sleep Disorders
Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities
The purpose of this study is to establish the efficacy and safety of Circadin in children with neurodevelopmental disorders and to determine the dose, this randomized, placebo-controlled study is planned to evaluate the efficacy…
- Trial name
- NCT01906866
- Testing
- Circadin 2/5/10 mg
- Where
- 28 sites in United States, Finland and 3 more
- Volunteers
- 125 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Hearing Loss, Sensorineural, Hearing Loss, Cochlear
Usability of the Intracochlear Catheter INCAT - a Feasibility Study
This is a feasibility study for a inner ear catheter which will be used to apply steroids to the inner ear. It will be used on nearly deaf patients during their surgery, when they receive an implant that will restore the hearing.
- Trial name
- INCAT (NCT06218966)
- Testing
- intracochlear catheter
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Postoperative
Intraoperative Lidocaine Infusion as a Sole Analgesic Versus Morphine in Laparoscopic Gastric Bypass Surgery
Postoperative opioid-centric pain management strategies in obese patients are accompanied by the possible development of; opioid-induced ventilatory impairment (OIVI) and hypoxemia.
- Trial name
- NCT05150756
- Testing
- Lidocaine Hydrochloride 2% Intravenous Solution [XYLOCAINE], morphine sulphate (10mg/ ml ampoule)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Myotonic Dystrophy 1
Poor Neck Proprioception May Cause Balance Deficits in Myotonic Dystrophy 1
Impairment of balance and gait are frequent complaints in patients with myotonic dystrophy type 1 (DM1). In these persons, there is an increased risk for stumbles and falls when compared to normal subjects.
- Trial name
- CABLAMYD (NCT04712422)
- Testing
- Healthy subjects, Pathologic group
- Where
- 2 sites in Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Auxologico Italiano
Color Vision Defects, Color Blindness
Performance of Red Tinted Contact Lenses on Colour Defects
This study aimed to relate and compare the performance of 4 types of red-tinted contact lenses (CL) with the Total Error Score (TES) from the Farnsworth-Munsell 100 Hue test on colour deficient subjects.
- Trial name
- CL (NCT05643222)
- Testing
- red tint contact lenses
- Where
- Malaysia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Breast Cancer, Prostate Cancer
Potential Vertebroplasty Use in the Treatment of Vertebral Metastasis From Breast and Prostate Cancer
The study aims to evaluate if adding vertebroplasty to radiotherapy, in the treatment of spine metastasis from breast and prostate cancer, is preferable to radiotherapy alone.
- Conditions
- Breast Cancer, Prostate Cancer, Vertebral Metastasis, Pain
- Trial name
- NCT00294151
- Testing
- Vertebroplasty
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain
A Study Comparing PF-05089771 TS Capsule To PF-05089771 TS Oral Dispersion In The Fasted State
The primary purpose of this study is to estimate the relative bioavailability and food effect of a PF-05089771 capsule.
- Trial name
- NCT01690351
- Testing
- PF-05089771
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pain, Postoperative Pain
Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins
The aim of this study is to compare the effect of Neem (azadirachta indica) and 2.5% sodium hypochlorite as root canal irrigants on the intensity of post-operative pain and the amount of endotoxins in necrotic teeth.
- Conditions
- Pain, Postoperative Pain, Postoperative Complications, Necrosis
- Trial name
- NCT03312153
- Testing
- Neem, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tubal Obstruction, Dysmenorrhea
Neural Therapy Effect and Bilateral Tubal Ligation
The aim of this study is to evaluate the effect of nebulisation in patients with bilateral tubal ligation in the first postoperative year, the amount of dysmenorrhea, dyspareunia and menstrual bleeding, recurrent vaginitis and…
- Trial name
- NCT03891537
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
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