Clinical trials: Neurologic Findings
Post-operative Pain
Pulsed Radiofrequency Energy to Treat Post-Bunionectomy Pain
Multicenter, randomized, controlled, double-blind study to evaluate the use of 3 days of pulsed radiofrequency energy (PRFE) to treat pain after bunionectomy surgery.
- Trial name
- NCT01694199
- Testing
- Pulsed Radiofrequency Energy (PRFE), No Pulsed Radiofrequency Energy (PRFE)
- Where
- 3 sites in United States
- Volunteers
- 139 people
- Sponsor
- Regenesis Biomedical, Inc.
Mild Cognitive Impairment (MCI), Dementia Alzheimer Type
Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort
The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia Alzheimer Type, Chronic Pain, Depression - Major Depressive Disorder
- Trial name
- KoCoA cohort (NCT07485387)
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Korea University
Chronic Pain, Chronic Non-cancer Pain
Personalized Care Management Model (GAP-421) for Chronic Pain in Primary Care Physiotherapy
This multicenter pilot study evaluates the feasibility, implementation fidelity, and preliminary effects of the GAP-421 (Personalized Care Management) model for chronic pain management in primary care physiotherapy.
- Conditions
- Chronic Pain, Chronic Non-cancer Pain, Care Coordination, Primary Health Care
- Trial name
- GAP-421 (NCT07451587)
- Testing
- GAP-421 Personalized Care Management Model
- Where
- 2 sites in Spain
- Volunteers
- 66 people
- Sponsor
- Universidad Autonoma de Madrid
Hearing Loss
Morphology Effects of Extended Wear Hearing Instrument
The lyric hearing device is a commercially available device produced by Sonova, and designed to be used for extended periods of time.
- Trial name
- NCT03902093
- Testing
- Morphology changes with extended wear hearing aid
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Postoperative Pain After Limb Lengthening, Limb Lengthening
Pain Beliefs and Functional Performance After Cosmetic Limb Lengthening Using the Lengthening Over Nail (LON) Technique
This pilot observational study aims to examine the relationship between pain beliefs, pain intensity, and functional performance in individuals who have undergone cosmetic lower limb lengthening surgery using the Lengthening Over…
- Trial name
- LON-PILOT (NCT07438821)
- Testing
- Postoperative Functional and Pain Assessment
- Volunteers
- 58 people
- Sponsor
- Istanbul Aydın University
Sleep Quality, Vital Signs
The Effect of Eye Masks and Earplugs In Intensive Care Unit Patients
This study was planned as a randomized controlled and experimental study to evaluate the effect of eye masks and earplugs on sleep quality and vital signs in intensive care patients.
- Trial name
- NCT05970614
- Testing
- Eye masks and ear plugs
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Osmaniye Korkut Ata University
Dysosmia, Anosmia
Treatment of Pediatric Patients That Lost Sense of Smell Due to COVID-19
This research study is a randomized controlled trial in pediatric and young adult patients who have lost their sense of smell due to COVID-19 viral infection. The goals are: 1.
- Conditions
- Dysosmia, Anosmia, Covid19
- Trial name
- NCT04964414
- Testing
- Smell Retraining, Budesonide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Amanda Stapleton
Hunger, Depression
Carbohydrate Rich Drink Reduces Pre-endoscopic Discomfort for Patients Going for Elective Endoscopic Procedures
The study is a randomised controlled trial that aims to evaluate whether carbohydrate loading pre-endoscopy can improve patients' overall satisfaction and is not associated with negative impact on endoscopic quality or increased…
- Conditions
- Hunger, Depression, Anxiety, Vomiting
- Trial name
- NCT05342116
- Testing
- Nestle Preload, Water
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Stroke, Ischemic, Aphasia
Individualized Precision rTMS for Language Recovery in Patients After Ischemic Stroke: a Multi-center RCT
The current multi-center study aims to evaluate the efficacy and safety of pBFS-guided rTMS Neuromodulation Treatment for the rehabilitation of language functions in ischemic stroke aphasic patients.
- Trial name
- NCT05842304
- Testing
- active cTBS
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Changping Laboratory
Joint (Knee or Hip Replacement)
The Impact of Extending Sleep Before Joint-replacement Surgery on Post-surgical Pain
This study will evaluate the impact of sleep banking on joint replacement surgery recovery.
- Trial name
- NCT07383584
- Testing
- Sleep banking
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Low Back Pain
Efficacy of Motor Control and Diathermy Treatment in Acute Low Back Pain
Lumbar pain is considered one of the most frequent health problems faced by human populations on a global scale. This study will be carried out to evaluate the efficiency of motor control treatments combined with diathermy in…
- Trial name
- NCT03386084
- Testing
- microwave diathermy
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- University of Alcala
Serratus Anterior Plane Block, Erector Spinae Plane Block
Serratus Anterior Plane Block Versus Erector Spinae Plane Block With Dexmedetomidine Added to Bupivacaine for Ultrasound-Guided Pain Management After Mastectomy
This study aimed to compare the serratus plane block versus the erector spinae plane block with dexmedetomidine added to bupivacaine for acute pain management after breast surgeries.
- Conditions
- Serratus Anterior Plane Block, Erector Spinae Plane Block, Dexmedetomidine, Bupivacaine
- Trial name
- NCT06737458
- Testing
- Bupivacaine + Dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Myopia, Amblyopia
Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults
Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of…
- Conditions
- Myopia, Amblyopia, Refractive Error - Myopia Axial, Ametropia
- Trial name
- MCPT (NCT05957458)
- Testing
- Airdoc device of red light for Myopia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Pain, Delirium
Longitudinal Cohort Study - for the Treatment of Acute Postoperative Pain and Postoperative Delirium, Postoperative Cognitive Dysfunctions, and Chronic Pain.
Adequate pain therapy is important aspect of perioperative care. Sequelae of inadequate pain management are patient dissatisfaction, post-operative nausea and vomiting (PONV), inadequate nutrition, lack of mobilization, and an…
- Conditions
- Pain, Delirium, Postoperative Cognitive Dysfunction
- Trial name
- NCT03133858
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Neuralgia, Spinal Cord Stimulation
Examining Carryover Effect in Patients Treated witH Spinal cOrd Stimulation (ECHO)
Spinal cord stimulation is a minimally invasive surgical treatment for severe, chronic, neuropathic pain that is refractory to conventional treatment.
- Trial name
- ECHO (NCT03386058)
- Testing
- Temporary device deactivation
- Where
- 10 sites in Belgium, Canada and 4 more
- Volunteers
- 200 people
- Sponsor
- University of Aarhus
Mitochondrial Myopathies, Mitochondrial DNA Mutation
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine
This study is an observational longitudinal study involving the use of MRIs and video recordings taken at home of patients completing basic tasks.
- Conditions
- Mitochondrial Myopathies, Mitochondrial DNA Mutation, Mitochondrial Diseases, Chronic Progressive External Ophthalmoplegia With Myopathy
- Trial name
- NCT05012358
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Postoperative Delirium
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day.
- Trial name
- NCT03291626
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Washington University School of Medicine
Pain
Catheter Orifice Configuration (Six-hole Versus End-hole) on Post-operative Analgesia After Total Knee Arthroplasty.
Multiorifice catheters have been shown to provide superior analgesia and significantly reduce local anesthetic consumption compared with end-hole catheters in epidural studies.
- Trial name
- NCT03376178
- Testing
- lidocaine and ropivacaine injection through catheters
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- University Hospital, Geneva
Analgesia
Liposomal Bupivacaine Versus Non-liposomal Bupivacaine for Total Shoulder Arthroplasty
The objective of this study is to validate the analgesic efficacy of admixed Liposomal bupivacaine (LB) + bupivacaine compared with plain bupivacaine when injected for interscalene nerve block (ISNB) for total shoulder…
- Trial name
- NCT04974385
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Virginia
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