Clinical trials: Neurologic Gait Disorder
Parkinson Disease
The Efficacy and Mechanism of SMA+M1 Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
This study is a double-blinded randomized study examining the efficacy of the double-site (M1+SMA) repetitive transcranial magnetic stimulation on Freezing of Gait (FOG) in patients with Parkinson's disease.
- Trial name
- NCT06415682
- Testing
- SMA+M1 Transcranial Magnetic Stimulation, M1 Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Severe Traumatic Brain Injury, Gait Disorders, Neurologic
Vestibular Rehabilitation and Severe Traumatic Brain Injury
Severe brain injury (sTBI) is one of the most common causes of long-term disability and is considered the most frequent cause of mortality and serious disability in young adults in industrialized countries.
- Trial name
- NCT04415580
- Testing
- Vestibular Rehabilitation (VR), Conventional Neurorehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Walking, Cognitive Function
Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia
The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia…
- Trial name
- NCT00494689
- Where
- 2 sites in Singapore
- Volunteers
- 30 people
- Sponsor
- Devathasan Neurology Practice Pte Ltd
Cerebral Palsy
The Efficacy of a RAGT & BWSTT on Children With CP
This study compared the effects of Robotic-assisted Gait Training (RAGT) and body weight support treadmill training (BWSTT) on spatio-temporal gait parameters and walking capacity among ambulatory children with bilateral Cerebral…
- Trial name
- NCT06368180
- Testing
- Robotic assisted gait training, Body weight supported treadmill training
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Saud University
Parkinson Disease
Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders
The trial will include 51 adult participants with Parkinson's disease and postural instability and gait disorders (PD-PIGD) and 20 age- and sex-matched healthy controls.
- Trial name
- NCT06868160
- Testing
- Rehabilitation, tDCS, tsDCS (first cycle)
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Spinal Cord Injuries
Low Oxygen Therapy to Enhance Walking Recovery After SCI.
The purpose of this study is to determine how combining bouts of low oxygen, transcutaneous spinal cord stimulation, and walking training may improve walking function for people with chronic spinal cord injury of different age…
- Trial name
- BO2ST-II (NCT06521723)
- Testing
- Daily acute intermittent hypoxia, Walking + tSTIM
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke
Dynamic Hot Spring Hydrotherapy for Gait Disorders and Balance Function Recovery After Stroke
Our research aims to analyze and compare the improvement of various indicators of gait disorders and balance function before and after dynamic hot spring hydrotherapy and conventional exercise intervention, and clarify the…
- Trial name
- NCT06955182
- Testing
- Dynamic hot spring hydrotherapy intervention, Conventional rehabilitation intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stroke
The Combining rTMS With Visual Feedback Training for Patients With Stroke
After stroke, patients often experience motor deficits that interrupt normal lower extremity movement and gait function. Recent developments in neuroimaging have focus on the reasons why some patients recover well while some do…
- Trial name
- rTMS (NCT03689491)
- Testing
- rTMS, visual feedback training, traditional rehabilitation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Hospital
Gait Analysis
An Ankle-foot Orthosis Improves Gait Performance and Satisfaction in Stroke Patients
All participants were at least 6-month post-stroke and had unilateral limb involvement (8 right/4 left). The main inclusion criteria in selection of the participants in this study were as follows :(1) First stroke (2) At least 6…
- Trial name
- NCT03965715
- Testing
- 3D printing AFO, anterior AFO, off-the-shelf AFO
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Bilateral Spastic Cerebral Palsy, Cerebral Palsy
Effect of Treadmill Gait Training Combined With Conventional Physiotherapy on Gait Performance and Functional Mobility in Children With Bilateral Spastic Cerebral Palsy: A Randomized Controlled Trial
Cerebral palsy is a neurological condition that affects movement, muscle control, and walking ability in children. Children with bilateral spastic cerebral palsy often experience increased muscle stiffness, difficulty with…
- Conditions
- Bilateral Spastic Cerebral Palsy, Cerebral Palsy, Spasticity Due to Cerebral Palsy, Gait Abnormality
- Trial name
- GAIT-CP (NCT07683338)
- Testing
- Treadmill Gait Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Syeda Khatoon e Jannat Welfare Foundation
Acquired Brain Injury
Does Improved Ability to Achieve Single Leg Stance Lead to a More Efficient Gait Pattern in Adults With Acquired Brain Injury?
The purpose of the study is to see if a person can stand better on their weaker leg does this improve their walking ability following treatment specifically aimed at standing on leg.
- Trial name
- NCT04062149
- Testing
- single leg stance treatment, Usual physiotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Stroke, Acute
Physiological Complexity of Gait Over the First Six Months Post Stroke
Physiological complexity of gait, a measure of the interaction of multiple control mechanisms for walking within a biological system, is decreased in persons with chronic stroke compared to those without disability.
- Trial name
- NCT02541578
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Indianapolis
Other Disorders of Autonomic Nervous System
Interval Training and Parkinson's Disease
This research is designed to compare the impact of high-intensity interval training and high-velocity circuit resistance training on heart rate variability, gait, and functional performance in patients with Parkinsons disease.
- Trial name
- NCT06606743
- Testing
- High-Intensity Interval Training, High-Velocity Circuit Resistance Training
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of Miami
Stroke
Comparative Effects of Motor Relearning Programme Versus Mirror Therapy on Balance and Gait in Chronic Stroke Patients
To determine the effect of Motor Relearning Program versus Mirror Therapy for balance and gait in chronic ischemic stroke patients
- Trial name
- NCT05810857
- Testing
- Motor Relearning Program, Mirror Therapy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Superior University
Stroke
Comparison of Robot-assisted Gait Training According to Gait Speed in Participants With Stroke
Comparison of the experimental group that applied the speed of the robot-assisted gait training constantly and the control group that applied the gradual increase of the speed of the robot-assisted gait training.
- Trial name
- NCT03991364
- Testing
- Constant gait speed group, Increasing gait speed group
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Cerebral Palsy (CP), Spastic Paraplegia
Retrospective Study on the WalkOn AFO in Children or Teenagers With Neurological Pathologies
The goal of this observational study is to assess the interest of prefabricated carbon fiber ankle foot orthoses (AFO) in children and teenagers with central or peripheral neurological pathologies.
- Conditions
- Cerebral Palsy (CP), Spastic Paraplegia, Spinal Cord Injuries (SCI), Spina Bifida
- Trial name
- NCT06740006
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Otto Bock France SNC
Musculoskeletal Injury, Musculoskeletal Diseases
The Effects of AFO Heel Height and Stiffness on Gait
The proposed study evaluates the effect of ankle foot orthosis (AFO) heel height and stiffness on the forces and motion of the lower limb during over-ground walking in individuals who use an AFO for daily walking.
- Conditions
- Musculoskeletal Injury, Musculoskeletal Diseases, Peripheral Nervous System Diseases
- Trial name
- AFOHeel (NCT04800484)
- Testing
- Tall Soft, Tall Firm, Short Soft
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Iowa
Multiple Sclerosis
Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis
Nearly 1 million individuals in the United States have multiple sclerosis, which causes fatigue and problems with walking. Fatigue and walking problems are poorly treated, but exercise training, particularly high-intensity…
- Trial name
- NCT06264336
- Testing
- treadmill training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Illinois Chicago
Parkinson Disease, Kinesiotaping
Short-term Effects Kinesiotaping (KT) on Balance and Gait in Parkinson's Disease (DP)
To analyze the short-term effect of kinesiotaping in balance and gait on Parkinson's disease
- Trial name
- KT-DP (NCT04326647)
- Testing
- Kinesiotaping, Exercise
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- University of Castilla-La Mancha
Gait Disorder, Sensorimotor, Cognitive Disorder
Thinking, Walking Outcomes by Type of Exercise
The purpose of this research study is to compare two different exercise treatments for walking problems in older adults. The investigators want to determine if participation in the exercise programs will improve walking and…
- Trial name
- 2-STEP (NCT01635348)
- Testing
- motor skill gait exercise, aerobic gait intervention
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
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