Clinical trials: Neurologic Gait Disorder
Parkinson Disease, Gait
Computer-based Cognitive Training for Parkinson Disease
Parkinson's Disease (PD) is a neurodegenerative, progressive illness. It is a multi-system disease that influences not only the motor but also the cognitive and autonomic systems.
- Trial name
- NCT01121627
- Testing
- Computerized cognitive training
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Clalit Health Services
Stroke, Chronic Stroke
Neural Operant Conditioning
The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT06113965
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Stroke, Motor Activity
Gait Mate: Examining Neural Networks Engaged During Lower Extremity Movement in the MRI
Less than 50% of stroke survivors progress to independent community ambulation. Even among the stroke survivors who achieve independent ambulation, significant residual deficits persist in balance and gait speed, with 60% of…
- Trial name
- NCT03604367
- Testing
- GAITRite assessment
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stroke, Hemiplegia
The Effect of Robot-Assisted Gait Training With or Without Plantar Pressure Summary Feedback: Impact on Gait Symmetry and Balance in Hemiplegic Patients
The goal of this randomized, single-blind clinical trial is to learn whether a 4-week Lokomat-based gait training program with plantar pressure feedback can improve gait symmetry and balance in adult patients with chronic…
- Trial name
- NCT07336667
- Testing
- Lokomat robot assisted gait training, Plantar pressure summary feedback
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Yeonji Choi
Multiple Sclerosis
Intermittent vs Continuous Walking in People With Multiple Sclerosis
This study will compare the effectiveness of a traditional, continuous walking rehabilitation program for people with MS to the novel intervention of an intermittent or interval walking rehabilitation program.
- Trial name
- NCT03963492
- Testing
- Walking
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rutgers, The State University of New Jersey
Cerebellar Ataxia
Effects of High Intensity Stepping Training on Gait in Patients With Ataxia
The purpose of this study is to examine the effects of high intensity stepping training on gait recovery, including walking speed and endurance, in patients with cerebellar ataxia.
- Trial name
- NCT06450457
- Testing
- Polar H10 heart rate monitor, Therastride Treadmill System, VECTOR Bioness
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Gait Patterns in Dual-task Conditions in Patients With Amyotrophic Lateral Sclerosis
The investigators hypothesize a relevant impact of cognitive status over gait performance in patients with amyotrophic lateral sclerosis (ALS), contributing to poor mobility and representing a relevant risk for falls.
- Trial name
- NCT06541873
- Testing
- Clinical and gait evaluation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Parkinson Disease, Freezing of Gait
Moving Mindfully for Freezing in Parkinsons
The investigators will modify and evaluate the feasibility of a mindfulness intervention among people living with Parkinson disease (PD) and freezing of gait (FOG).
- Trial name
- MMR34 (NCT05309083)
- Testing
- Mindfulness Based Walking Therapy (MBWT)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Washington University School of Medicine
Stroke Sequelae, Spasticity, Muscle
Effects of CRet Associated With Functional Massage (F.M) on Gait and Functionality in Post-stroke Spasticity
The purpose of this study is to assess the immediate effects of CRet associated to Functional Massage (F.M) in terms of gait and functionality after stroke
- Conditions
- Stroke Sequelae, Spasticity, Muscle, Massage, Electrotherapy
- Trial name
- NCT04851756
- Testing
- CRet
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universitat Internacional de Catalunya
Parkinson Disease
Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease
The purpose of the study is to learn about the effect of GOCOVRI (Amantadine extended release) on activity levels and measures of gait and balance quality in people with Parkinson's disease (PD) and levodopa induced dyskinesia…
- Trial name
- NCT04387773
- Testing
- GOCOVRI
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Oregon Health and Science University
Cerebral Palsy
The Effectiveness of Robotic Assisted Gait Training as an Adjunct to Traditional Physiotherapy in Cerebral Palsy
Need for study There are a few studies published on this topic from various parts of the globe and the results are mixed. Hence further research is required in this area and none of the studies have included samples from the…
- Trial name
- RAGT (NCT04960683)
- Testing
- Lokomat training
- Where
- United Arab Emirates
- Volunteers
- 41 people
- Sponsor
- Fatima College of Health Sciences
Ischemic or Hemorrhagic Stroke, Hemiparesis
Aquatic Treadmill Therapy for Improving Gait, Balance, Fitness and Quality of Life in Stroke Patients
This study aims to determine if Aquatic Treadmill Therapy is effective for improving economy of gait, gait speed, balance, and cardiovascular fitness in people with chronic stroke.
- Trial name
- ATT (NCT00983827)
- Testing
- Aquatic treadmill training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Utah
Cerebral Palsy (CP), Unilateral Spastic Cerebral Palsy
Short-Term Effects of Manual Therapy Prior to Neuromotor Therapy in Children With Cerebral Palsy
This pilot study aims to evaluate the immediate, short-term biomechanical and neuromuscular effects of lower limb manual therapy applied as a preparatory phase prior to functional neuromotor rehabilitation in children with…
- Conditions
- Cerebral Palsy (CP), Unilateral Spastic Cerebral Palsy, Bilateral Spastic Cerebral Palsy, Diplegic Cerebral Palsy With Spasticity
- Trial name
- NCT07902466
- Testing
- Manual Therapy (T1 & T3)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- LIFE - Research and Care Institute - Santa Lucia IRCCS
Parkinson Disease, Gait Disorders
The Effect of Balance-focused Exercise Programme in Enhancing the Solus-muscle Activation During Gait Initiation for People With Parkinson Disease
Gait initiation (GI) is a crucial component of walking that requires a balanced muscle activity and postural stability. GI could be challenging for people with neurological condition such as people with Parkinson (PWP), where GI…
- Conditions
- Parkinson Disease, Gait Disorders, Gait Balance
- Trial name
- NCT07263646
- Testing
- balance-focus exercise programe
- Where
- Kuwait
- Volunteers
- 80 people
- Sponsor
- Ministry of Health, Kuwait
Sarcopenia, Gait Disorders in Old Age
A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)
The main objective of the study is to evaluate the effect of two daily doses of BIO101 versus placebo on mobility function as measured by gait speed using the 400MW test.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-INT (NCT03452488)
- Testing
- BIO101
- Where
- 22 sites in United States, Belgium
- Volunteers
- 233 people
- Sponsor
- Biophytis
Multiple Sclerosis, Gait Disorders, Neurologic
Reliability of Kinovea in Gait Assessment in Multiple Sclerosis: a Pilot Study.
The objective of this observational study is to determine whether the Kinovea video analysis tool is valid and reliable for analyzing spatiotemporal gait parameters in multiple sclerosis, comparing the data obtained from this…
- Trial name
- KV-MS (NCT06928194)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- University of Cadiz
Ataxia, Gait
Ataxia GAA-FGF14 - Descriptive Genetic and Clinical Study
Cerebellar ataxias of late onset are of undetermined etiology in many cases. A new cause of late-onset cerebellar ataxia was discovered in January 2023 corresponding to an expansion of GAA triplets in intron 1 of the FGF14 gene.
- Trial name
- GAA-FGF14 (NCT05884086)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Stroke
Beren Vibration Insole in Stroke Rehabilitation
The aim of this study is to investigate the effects of a custom-made vibration insole on gait, balance, and fall risk in patients with stroke.
- Trial name
- NCT07898579
- Testing
- Conventional Physiotherapy, Plantar Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bitlis Eren University
Parkinson's Disease
Transcranial Direct Current Stimulation (tDCS) and Parkinson's Disease
The use of low level electrical stimulation when applied over the head, also called transcranial direct current stimulation (tDCS), is being tested by several groups of researchers to see if tDCS can improve movements of persons…
- Trial name
- NCT01100762
- Testing
- Cranial Electric Stimulation (CES), Treadmill, CES and Treadmill
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Stroke
PEMOCS: Personalized Motor-cognitive Training in Chronic Stroke
In Switzerland, approximately 20'000 persons suffer a stroke each year. Despite carefully considered rehabilitation programs, full recovery is achieved only in a small proportion of stroke survivors (www.swissheart.ch).
- Trial name
- NCT05524727
- Testing
- Concept-guided, personalized, motor-cognitive training by means of an exergame
- Where
- 3 sites in Switzerland
- Volunteers
- 38 people
- Sponsor
- University of Zurich
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