Clinical trials: Neurologic Gait Disorder
Multiple Sclerosis
Comparison of Two Community Based Exercise Protocols in People With Multiple Sclerosis
This study will compare the benefits of two community based exercise programs, personal training and whole body vibration on balance and gait in people with Multiple Sclerosis.
- Trial name
- NCT03429062
- Testing
- Personal training exercises
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Woman's University
Gait, Spastic
Weight Distribution Asymmetry in Relation to Speed During Gait in Children With Spastic Cerebral Palsy.
Background: Improving walking ability is one of the major concerns in therapeutic interventions for children with cerebral palsy.
- Trial name
- NCT04636424
- Testing
- assesment of gait
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Cairo University
Parkinson Disease
Comparison of Different Rehabilitation Protocols in Parkinson's Disease With Postural Instability and Gait Disorders
The aim of the study is to compare the effects of 2 different dosages and modalities of motor-cognitive rehabilitation in Parkinson's disease with postural instability and gait disorders (PD-PIGD) on clinical features…
- Trial name
- NCT05799690
- Testing
- Gait and balance training with dual-task + action observation and motor imagery (six weeks), Gait and balance training with dual-task (six weeks), Gait and balance training with dual-task + action observation and motor imagery (twelve weeks: 6 + 6)
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Massimo Filippi
Parkinson's Disease
Long-term Effect of Low Frequency Stimulation on Aspiration and Freezing of Gait in PD With STN DBS
Our recent study (Xie et al, Neurology 2015; 84: 415-420) found that bilateral STN DBS of 60Hz, compared to the traditional 130Hz, decreased the aspiration frequency and swallowing difficulty, freezing of gait (FOG), and other…
- Trial name
- NCT02549859
- Testing
- Deep Brain Stimulation (DBS) at 60 Hz, Deep Brain Stimulation (DBS) at 130 Hz
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Chicago
Spinal Cord Injuries (SCI)
RTsMS and Body Weight-support Treadmill Training After Incomplete Spinal Cord Injury
The aim of this study is to assess the feasibility of combining rTsMS with BWSTT for gait and sensorimotor recovery in individuals with incomplete spinal cord injury.
- Trial name
- NCT06886308
- Testing
- Repetitive trans-spinal magnetic stimulation
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- Universidade Federal de Pernambuco
Multiple Sclerosis, Vestibular
The Effects of Vestibular Exercise and Cervical Stabilization Exercise Training on Balance and Gait in MS Patients
The population of this research consists of individuals between the ages of 18-65 with MS disease. MS patients to be included in the study will be directed by the Neurology outpatient clinic of Sanko University Hospital.
- Conditions
- Multiple Sclerosis, Vestibular, Exercises
- Trial name
- NCT05409599
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Sanko University
Parkinson Disease, Gait Disorders
Effects of Biofeedback Footwear in Parkinson's Disease: Assessment of Functional Motor Abilities and Locomotion
The study aims to verify whether the use of a specific footwear providing increased plantar feedback (plantar feedback shoes) could improve gait parameters, postural control and functional performances in people with Parkinson's…
- Trial name
- NCT06453863
- Testing
- Greater plantar feedback shoes, Neutral gym shoes, Barefoot
- Volunteers
- 40 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Gait Disorders, Neurologic
Transcutaneous Magnetic Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease
Dopaminergic drugs partially alleviate gait problems in Parkinson's disease, but the effects are not sustained in the long-term.
- Trial name
- TMS (NCT04783493)
- Testing
- Non-invasive magnetic stimulation of the spinal cord, Coil will not be connected to the stimulation device
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Spastic Cerebral Palsy (sCP)
Stop Tip-toeing Around Toe-walking
The purpose of this study is to explore the interplay among nervous-, musculoskeletal-, and psychological systems and how they impact toe-walking behavior, and vice versa.
- Trial name
- NCT04879199
- Testing
- Static stability measurement, Dynamic stability measurement
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Spinal Muscular Atrophy Type 3, Ambulatory Spinal Muscular Atrophy
Gait and Bone Health in SMA
The objective of this study is to understand how spatiotemporal and kinetic gait parameters are associated with bone health in pwSMA who are receiving DMT.
- Trial name
- NCT07400198
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Jacqueline Montes
Incomplete Spinal Cord Injury
Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury
Spinal cord injury (SCI) affects ~42,000 Veterans. The VA provides the single largest network of SCI care in the nation. The lifetime financial burden of SCI can exceed $3 million. A major cost of SCI is impaired mobility.
- Trial name
- AGILE SCI (NCT04340063)
- Testing
- Gait training performed on a treadmill, Gait training performed in a Movement Amplification Environment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Parkinson Disease
Combined Deep Brain Stimulation in Parkinson's Disease
The study is a pilot study on Parkinson's disease patients to evaluate Combined deep brain stimulation of the substantia nigra pars reticulata and of the subthalamic nucleus for unresponsive freezing of gait.
- Trial name
- SCP-FOG (NCT05415774)
- Testing
- 1 : S-C1-C2, 2 : S-C2-C1, 3 : C1 - S - C2
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Stroke, Acute
Physiological Complexity of Gait Over the First Six Months Post Stroke
Physiological complexity of gait, a measure of the interaction of multiple control mechanisms for walking within a biological system, is decreased in persons with chronic stroke compared to those without disability.
- Trial name
- NCT02541578
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Indianapolis
Multiple Sclerosis, Balance Impairment, Gait Disorders, Fatigue
The Effect of Task-Oriented Training and Virtual Reality Training on Balance, Gait and Fatigue in Individuals With Multiple Sclerosis
Introduction: Multiple sclerosis (MS) is a chronic disease of the central nervous system. Task-focused training is an approach that relies on multiple repetitions of motor performance.
- Conditions
- Multiple Sclerosis, Balance Impairment, Gait Disorders, Fatigue, Multiple Sclerosis Bening, Multiple Sclerosis Relapsing Remitting
- Trial name
- NCT07000968
- Testing
- Virtual Reality Training Group, Task-Oriented Training Group, Conventional Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Inonu University
Parkinson's Disease
Frontal Cortex and Gait Freezing in Parkinson's Disease: Rehabilitation Impact
This project will relate our new quantification of Freezing of Gait (FoG) in Parkinson's disease, using body worn inertial sensors (Aim I), with abnormalities in state-of-the-art, resting state, functional brain connectivity (Aim…
- Trial name
- NCT02236286
- Testing
- Exercise
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Spastic Cerebral Palsy
Forward Versus Backward Gait Training on Functional Abilities in Children With Spastic Cerebral Palsy
This study aims to compare the effects of forward versus backward gait training on functional abilities in children with spastic cerebral palsy.
- Trial name
- NCT07251751
- Testing
- control group ( designed physical therapy program), forward gait training, backward gait training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Parkinson Disease
Vibrational Therapy to Improve Gait and Balance in Parkinson's Disease
The purpose of this research study is to determine optimum dose of vibration delivered by an experimental device called PDVibe2 required to treat freezing of gait in persons with Parkinson's disease (PD).
- Trial name
- NCT03872115
- Testing
- PDVibe2
- Sponsor
- Virginia Commonwealth University
Chronic Stroke, Proprioceptive Neuromuscular Facilitation
Effects of Motor Relearning Program Versus Proprioceptive Neuromuscular Facilitation on Balance and Gait in Stroke
A randomized control trial will be done on diagnosed stroke patients of chronic stage in DHQ Hospital Mirpur and FF Hospital Rawalpindi physical therapy Department.The purpose of the study is to determine Effects of Motor…
- Conditions
- Chronic Stroke, Proprioceptive Neuromuscular Facilitation, Balance, Gait
- Trial name
- NCT06674590
- Testing
- Proprioceptive Neuromuscular Facilitation, Motor Relearning Program
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Foundation University Islamabad
Cerebral Palsy
Innovative Robotic Gait Trainer Use to Enable Walking in Children With Cerebral Palsy GMFCS III and IV
Exploration to optimize mixed quantitative and qualitative methodology using multiple outcome measures in a randomized, cross-over trial structure comparing the effect of robotic gait training (RGT) group, and functional clinical…
- Trial name
- NCT05378243
- Testing
- Robotic Gait Training, Functional Clinical Therapy
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Eastern Ontario
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