Clinical trials: Neurologic Gait Disorder
Parkinson Disease, Freezing of Gait
Vibrotactile Foot Device for Freezing of Gait in Parkinson's Disease
Freezing of gait (FOG) is a common, disabling symptom of later stage Parkinson's disease (PD), and can induce significant morbidity and mortality by increasing risk of falls as the disease progresses.
- Trial name
- NCT06147713
- Testing
- Vibrotactile foot device (Smart shoe)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Effect of Repeated Injections of Higher Doses of Botulinum Toxin on Lower Limb of Spastic Hemiplegic Patients on Gait.
1. To show that repeated injections of higher doses of botulinum toxin are significantly more effective than the injection of unique, lower doses, on gait function. 2.
- Trial name
- NCT04544280
- Testing
- Xeomin Injectable Product
- Where
- 2 sites in Belgium
- Volunteers
- 32 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Stroke
Enhanced Treadmill Gait Training With Lower Limb Support After Stroke
This series of single case studies aims to test the feasibility and acceptability of an enhanced treadmill system for the recovery of gait function in stroke survivors.
- Trial name
- ENTRES (NCT03348215)
- Testing
- Enhanced Treadmill Training
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Strathclyde
Telemedicine, Gait, Hemiplegic
Treatment of Hemiparetic Gait Impairments Using Telehealth With the Moterum iStride Solution™
The objective of this research is to investigate the feasibility of delivering gait treatment using the Moterum iStride Solution™ to individuals with hemiparetic gait impairments using a telemedicine modality, the Moterum Digital…
- Conditions
- Telemedicine, Gait, Hemiplegic, Gait Disorders, Neurologic, Stroke
- Trial name
- NCT04434313
- Testing
- Delivery of iStride™ device gait treatment using telemedicine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Moterum Technologies, Inc.
Parkinson Disease
Sensor-supported Classification of Gait Patterns in Everyday Movement of Patients With Parkinson's Disease
Within this study we conduct long-term measurements on Parkinson patients using a three sensor IMU setup: one sensor is located at the wrist, one sensor at the belt/ in the pocket and one sensor is worn as a pendant.
- Trial name
- PD-GPC (NCT04054856)
- Testing
- Body Sensor Network
- Where
- Germany
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Obstructive Sleep Apnea
To Study the Impact of CPAP on Gait Parameters in OSA Patients
To study the impact of CPAP therapy on gait in patients with obstructive sleep apnea syndrome.
- Trial name
- OSA_Gait (NCT02061046)
- Testing
- CPAP therapy
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
Diabetes, Diabetic Foot
10 Years Follow-up Study of Plantar Pressure, Kinetics and Kinematics in a Cohort of Patients Diagnosed With Diabetes
A combination of diabetes and neuropathy can cause an altered gait, increased tissue stiffness, limited joint mobility, muscle weakness, foot deformities, thus leading to excessive plantar pressure.
- Conditions
- Diabetes, Diabetic Foot, Plantar Ulcer, Neuropathy
- Trial name
- Diab10 (NCT04054076)
- Testing
- Prefabricated insoles, Soft custom-made insoles, Hard custom-made insoles
- Where
- Sweden
- Volunteers
- 224 people
- Sponsor
- Sahlgrenska University Hospital
Parkinson Disease, Parkinson
Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease.
Examining the feasibility and acceptability of the computer game based rehabilitation system for improving balance, gait and executive function in individuals with PD.
- Trial name
- NCT03232996
- Testing
- Computer game based balance and walking rehabilitation for individuals with Parkinson's Disease
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Stroke, Ischemic
Effects of PNF Patterns Training on Trunk Balance, and Gait in Chronic Stroke Patients
To determine the effects of PNF patterns Training on trunk balance and gait in chronic stroke patients.
- Trial name
- NCT05221112
- Testing
- diagonal pattern training, single plane training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Stroke, Acute Stroke
Soft Exosuits for Functional Gait Recovery in Acute Stroke Rehabilitation
The purpose of this study is to develop and evaluate the use of soft exosuits in patients post stroke.
- Trial name
- NCT06231511
- Testing
- Hip flexion soft exosuit, ReWalk ReStore soft exosuit, Conventional physical therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Shirley Ryan AbilityLab
Parkinson Disease
A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease
The primary objective of this study is to investigate the effects of a theoretically driven, highly challenging exercise program (balance and strengthening exercises) in reducing fall rate, improving balance and reducing fear of…
- Trial name
- NCT02302144
- Testing
- Balance & Strengthening Exercises
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Boston University Charles River Campus
Cerebral Palsy (CP)
Effect of Multidimensional Trunk Training in Children With Cerebral Palsy
This study investigates the effects of a personalized, multidimensional trunk-focused exercise program combined with conventional rehabilitation on postural control, gait, selective motor control, spasticity, activity…
- Trial name
- NCT07034872
- Testing
- Control Group, Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
FIRST-Oslo Long-term Follow-up
The study aims to describe the functional level of the patients who received high intensity gait training during inpatient stroke rehabilitation at discharge, three, six and twelve months after stroke.
- Trial name
- NCT04870619
- Testing
- High Intensity Gait Training
- Where
- 2 sites in Norway
- Volunteers
- 69 people
- Sponsor
- Oslo University Hospital
Normal Pressure Hydrocephalus
White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)
Idiopathic Normal Pressure Hydrocephalus (iNPH) is a progressive condition of the elderly that results in severe disability. iNPH can dramatically respond to Cerebral spinal fluid(CSF)-shunting where excess ventricular fluid is…
- Trial name
- OWN-NPH (NCT07103681)
- Testing
- Ventriculoperitoneal Shunt (VP), Brain and Skin Biopsy, MRI Brain
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Diplegic Cerebral Palsy
Influence of Surface Characteristics of Gait Training on Gait Kinematics and Walking Capacity in Children With Diplegic CP
Using challenging surfaces of gait training, which require constant adjustments of the body's movement patterns to maintain stability and provide different sensory and proprioceptive inputs to mimic real life situation is…
- Trial name
- NCT05420363
- Testing
- different walking surfaces, traditional gait training over hard surface only
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Palsy, Equinus Foot Deformity in Children With Cerebral Palsy
Percutaneous Needle Technique is Comparable to Open Z-plasty Surgery for Unilateral Tendon Achilles Lengthening in Children With Cerebral Palsy
This study aims to compare the outcomes of two surgical techniques for Achilles tendon lengthening in ambulatory children with cerebral palsy (CP): the percutaneous needle technique and the traditional open Z-lengthening…
- Conditions
- Cerebral Palsy, Equinus Foot Deformity in Children With Cerebral Palsy, Gait Analysis in Neurological Disorders
- Trial name
- NCT06875011
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Vestre Viken Hospital Trust
Huntington's Disease
Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's Disease
In individuals with Huntington's disease (HD), chorea may contribute to balance problems and difficulties with walking, sit to stand transfers and stair climbing that in turn may contribute to high fall rates.
- Trial name
- NCT01451463
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Ohio State University
Older Adults (65 Years and Older), Balance
Gait Reeducation Program in Older Adults
The sequential square mat (SSM) Fisior® program is a novel functional gait training tool designed to enhance motor control, coordination, and strength through guided step sequences on a visual-tactile platform.
- Conditions
- Older Adults (65 Years and Older), Balance, Gait Disorders, Physical Performance
- Trial name
- NCT07006584
- Testing
- Experimental, Active Comparator #1
- Where
- Peru
- Volunteers
- 47 people
- Sponsor
- Universidad Europea de Madrid
Stroke
HIT-Stroke Trial 2
People who had a stroke at least 6 months prior and who still have difficulty with walking will each be randomly assigned to receive either moderate or vigorous intensity walking exercise.
- Trial name
- HST2 (NCT06268041)
- Testing
- Moderate-Intensity Aerobic Training, High-Intensity Interval Training
- Where
- 3 sites in United States
- Volunteers
- 156 people
- Sponsor
- University of Cincinnati
Stroke
Virtual Reality Training Program for Ambulatory Patients With Chronic Gait Deficits After Stroke
The purpose of this study is to examine the feasibility and efficacy of a virtual reality program for ambulatory patients with mild-to-moderate chronic gait deficits after stroke.
- Trial name
- NCT00600379
- Testing
- Virtual reality system (CAREN™ Integrated Reality System; MOTEK BV, Netherlands).
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Sheba Medical Center