Clinical trials: Neurologic Gait Disorder
Stroke
Energy Consumption and Cardiorespiratory Load During Walking With and Without Robot-Assistance
The primary objective of the study is to investigate the energy consumption, cardiorespiratory load and perceived exertion, and how these parameters change, during walking with robot-assistance compared to walking on a treadmill…
- Trial name
- NCT02680496
- Testing
- Lokomat, Treadmill, Overground
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- Vrije Universiteit Brussel
Spinal Cord Injury
Validation of a Novel Robot-aided Assessment of Gait Ability
The aim of this study is the validation of a novel gait assessment method implemented in the Lokomat gait trainer with respect to established clinical gait assessment methods.
- Trial name
- NCT02425332
- Testing
- Lokomat gait trainer
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Parkinson Disease
The Effect of Upper Extremity Telerehabilitation on Balance and Gait
Parkinson's Disease (PD) is a disease that affects the upper extremity functional skills with clinical findings such as bradykinesia, rigidity, and hypokinesia and causes limitations in the daily living activities of the…
- Trial name
- NCT05971784
- Testing
- Telerehabilitation Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Gazi University
Neuromuscular Diseases, Obesity (Disorder)
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
The ActiLiège-Adult study is a prospective, longitudinal, observational study designed to collect natural history data on adult patients with neurological or metabolic diseases affecting movement.
- Conditions
- Neuromuscular Diseases, Obesity (Disorder), Myotonic Dystrophy 1, Myasthenic Syndrome
- Trial name
- Acti-Adult (NCT07136844)
- Testing
- Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Hereditary Spastic Paraplegia, Adrenomyeloneuropathy
Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy
Hereditary spastic paraplegia (HSP) is the group of inherited disorders, characterized by progressive gait disturbance. There is no established therapy. Adrenoleukodystrophy (AMN) is an x-linked hereditary disease.
- Trial name
- NCT03627416
- Testing
- rTMS
- Where
- Poland
- Volunteers
- 15 people
- Sponsor
- Jakub Antczak
Multiple Sclerosis
Quantifying Gait Alteration in Multiple Sclerosis Using a Wearable Device
Gait alteration is frequent in MS and limitation in walking ability is a major concern in MS patients. The development of wearable device offers the opportunity to collect data during daily activity including walking.
- Trial name
- eMSGait (NCT04969848)
- Testing
- Wearable sensor
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Nantes University Hospital
Parkinson Disease
Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.
The proposed system (haptic module and insole device) for daily in-community use that detects the occurrence of freezing of gait (FOG) in people with Parkinson's disease (PD).
- Trial name
- NCT06385392
- Testing
- Haptic module and insole device
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- HealthPartners Institute
Cerebral Palsy
Effectiveness of Robotic Assisted Gait Training in Children With Cerebral Palsy
The purpose of the study is to investigate the effectiveness of robotic-assisted locomotor therapy on improvements of functional gait parameters in ambulatory children with cerebral palsy.
- Trial name
- PeLoGAIT (NCT00887848)
- Testing
- Lokomat training
- Where
- 2 sites in Switzerland
- Volunteers
- 16 people
- Sponsor
- University Children's Hospital, Zurich
Stroke
Robotic Exosuit Augmented Locomotion (REAL)
Previous studies of the exosuit technology have culminated in strong evidence for the gait-restorative effects of soft robotic exosuits for patients post-stroke by means of substitution for lost function.
- Trial name
- REAL (NCT04818424)
- Testing
- Soft exosuit, Gait training without exosuits
- Where
- 3 sites in United States
- Sponsor
- Lou Awad, PT, DPT, PhD
Multiple Sclerosis
Virtual Reality and Robot Assisted Gait Training in Patients With Multiple Sclerosis
Multiple Sclerosis (MS), the most common non-traumatic cause of neurologic disability in young adults, affects mobility and ambulation in the majority of patients.
- Trial name
- GE-O-VR (NCT02896179)
- Testing
- Robot-assisted gait training group+VR, GEO
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Universita di Verona
Parkinson Disease
Effects of Magnetic Stimulation of the Dorsal Spinal Cord on Gait in Patients With Parkinson´s Disease and Deep Brain Stimulation
Gait disorders are symptoms that significantly compromise the quality of life and functionality of patients with Parkinson's disease (PD).
- Trial name
- TMS (NCT05008289)
- Testing
- Magnetic transcutaneous spinal cord stimulation, Transcutaneous electrical nerve stimulation
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo General Hospital
Cerebral Palsy (CP)
Does Orthopedic Surgery Improve Gait Efficiency in Children With Cerebral Palsy? A Retrospective Study
Purpose: The aim of this retrospective observational study is to describe the demographic, clinical, and functional characteristics of children and adolescents with spastic cerebral palsy (CP) undergoing Single Event Multilevel…
- Trial name
- OrthoSurg01 (NCT06624280)
- Testing
- single-event multilevel surgery
- Where
- 2 sites in Italy
- Volunteers
- 78 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Parkinson Disease
Effects of Nordic Walking Exercise on Gait, Motor/Non-motor Symptoms, and Exercise Biomarkers in Parkinson's Disease
The purpose of this study is to examine the effects of Nordic pole walking exercise on walking function, movement and non-movement Parkinson-related symptoms, and certain exercise-related chemical indicators (bio-markers) in…
- Trial name
- NCT04237025
- Testing
- Nordic walking exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Grand Valley State University
CVA (Cerebrovascular Accident)
Research Report: CERITER Clinical Study - Stride One
The goal of this clinical study is to investigate the short-term impact of the use of Ceriter Stride One on the quality of gait in patients rehabilitating after a cerebrovascular accident (CVA).
- Trial name
- NCT06560450
- Testing
- Stride One
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Ceriter Nederland BV
Spinal Cord Injuries (SCI), Spinal Cord Injury
Promoting Neuroplastic Mechanisms With Modeling-based Optimization of a Novel Robot-asisted Walking Rehabilitation Therapy
The goal of this observational study is to assess the course of motor and functional gait recovery induced by Lokomat robot-assisted gait rehabilitation in patients with spinal cord injury.
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Neurorehabilitation, Robot Assisted Gait Training
- Trial name
- NIMBLE (NCT07440459)
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- BioRobotics Group - Spanish National Research Council (CSIC)
Stroke, Hemiplegia
Impact of Hip Flexors Isokinetic Strengthening on Gait Capacities in Subacute Stroke Patients
Post-stroke patients often present with gait disorders due to several physical impairments. Hip flexor deficit is one of the more prevalent trouble and is associated with gait capacities.
- Conditions
- Stroke, Hemiplegia, Gait
- Trial name
- ISOKINETIC (NCT02917850)
- Testing
- Isokinetic hip flexors strengthening, Conventional rehabilitation
- Sponsor
- University Hospital, Lille
Multiple Sclerosis
Short and Long Term Multiple Outcomes in Persons With Multiple Sclerosis Treated by Fampridine.
This prospective monocentric open label trial was realized in the Laboratory of Clinical Functional Exploration of Movement at the University Hospital of Besancon.
- Trial name
- FAMPISEP (NCT02849782)
- Testing
- Fampridine
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Cerebral Palsy, Gait Disorders, Neurologic
Cognitive and Motor Tasks in Cerebral Palsy
Various gait deviations are observed in children with cerebral palsy. Our aim was to determine the effect of cognitive task (CT) and motor task (MT) on gait in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy, Gait Disorders, Neurologic, Cognitive Orientation, Motor Activity
- Trial name
- NCT04850690
- Testing
- 2D Gait analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Multiple Sclerosis
Muscle Fatigue in Patients With Multiple Sclerosis
It is stated that 85% of patients with Multiple Sclerosis (MS) complain of gait disorders and 35-90% of them have fatigue. Many factors play a role in the fatigue mechanism in MS patients.
- Trial name
- NCT04548310
- Testing
- Muscles Fatigue
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gazi University
Amyotrophic Lateral Sclerosis
From Movement Preparation to Gait Execution in ALS
This research program will focus on gait initiation and postural control in Amyotrophic Lateral Sclerosis (ALS) patients, by comparing patients with vs without postural instability (but also in comparison to controls), by using a…
- Trial name
- GAITALS (NCT01874808)
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
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