Clinical trials: Neurologic Rehabilitation
Parkinson Disease
Predicting Motor Learning of an Upper Limb Task Based on Behavioral and Disease-specific Characteristics in Patients With Parkinson's Disease
Manual dexterity deficits and loss of motor automaticity are commonly seen in patients with Parkinson's disease (PD). Amongst these problems, using a touchscreen is becoming increasingly burdensome.
- Trial name
- NCT06738290
- Testing
- Targeted home-based touchscreen training
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Stroke
Investigation of Acceptable Dose of Mobilisation and Tactile Stimulation to Enhance Upper Limb Recovery After Stroke
The purpose of this study is to find which of three doses of mobilisation and tactile stimulation therapy, when given in addition to conventional UK physical therapy, has the most beneficial effect on enhancing motor recovery of…
- Trial name
- NCT00360997
- Testing
- Conventional UK physical therapy, Con UK PT + Mobilisation & tactile stimulation (MTS)
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London
Stroke
Therapeutic Exercise for Patients With Stroke
The aim of this prospective, single-centre, non-randomized, single-arm interventional study is to evaluate changes in muscle strength, lower-limb functional capacity, aerobic endurance, and patient satisfaction following…
- Trial name
- EINTER (NCT07736794)
- Testing
- EINTER Therapeutic Exercise Programme
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Muscle Weakness, Gait, Unsteady
High Intensity Interval Training in Geriatrics
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
- Trial name
- HIITERGY (NCT02318459)
- Testing
- high intensity interval training-HIIT, Traditionnal group rehabilitation
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Critical Illness Myopathy, Critical Illness Polyneuropathy
Improved Recovery of Walking in Acquired Muscle Weakness
The aim of Re-Walk-Easy is to evaluate the effects of rehabilitation based on electrical stimulation on the motor performance of critically ill patients.
- Trial name
- Re-Walk-Easy (NCT06786390)
- Testing
- Rehabilitation protocol: FES, Rehabilitation protocol without FES
- Where
- Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Upper Extremity Paresis
Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke
Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ability to perform daily…
- Trial name
- RIITSTROKE (NCT07598435)
- Testing
- Rhythmic Initiation (PNF technique), Isometric Resistance Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
TBI (Traumatic Brain Injury) or MS (Multiple Sclerosis)
Improving Learning in Hispanics With TBI or MS
The goal of this study is to establish that a memory retraining protocol, originally developed for English-speakers, and translated into Spanish, is effective.
- Trial name
- NCT03453125
- Testing
- Spanish modified Story Memory Technique (mSMT)
- Where
- 2 sites in United States, Spain
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
CRPS (Complex Regional Pain Syndromes)
The Effectiveness of Conservative Treatment in Patients With Complex Regional Pain Syndrome.
The aim of the study is to investigate and improve non-pharmacological rehabilitation methods for patients with Complex Regional Pain Syndrome (CRPS) to reduce pain and restore work and functional capacity to lower overall…
- Trial name
- NCT07208825
- Testing
- rTMS, Basic physical therapy treatment, Functional neurology
- Where
- Finland
- Volunteers
- 156 people
- Sponsor
- Oulu University Hospital
Critical Illness
PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children
Recent decreases in Pediatric Intensive Care Unit (PICU) mortality rates have been offset by increased morbidity and length of stay for vulnerable young patients.
- Trial name
- PICU Up! (NCT03860168)
- Testing
- PICU Up!
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Johns Hopkins University
Stroke, Hemiparesis
Motor Imagery BCI Rehabilitation After Stroke
This research project will investigate motor imagery training in stroke rehabilitation during which patients receive feedback in real time from their brain activity measured with ElectroEncephaloGraphy (EEG).
- Trial name
- NCT04847089
- Testing
- Motor imagery BCI training
- Where
- 3 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Mälardalen University
Degenerative Lumbar Disease, Neuropathic Pain
Rehabilitation Interventions for Postoperative Degenerative Lumbar Disease
The purpose of this study is to evaluate the effects of different rehabilitation interventions on patients who have undergone surgery for degenerative lumbar disease.
- Trial name
- NCT07550660
- Testing
- Stretching and Core Stability Exercise Program (Group A), Core Stability Exercise Program (Group B), Standard Postoperative Nursing Care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Stroke, Cardiovascular
Effects of Thermal Stimulation on Motor Recovery and Neuromuscular Property of Lower Extremity in Stroke
This 3-year study will recruit a total of 72 subjects with first-ever stroke after 3 months onset from the department of Physical Medicine and Rehabilitation in 3 teaching hospitals.
- Trial name
- NCT04306120
- Testing
- Traditional Rehabilitation Therapy
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Multiple Sclerosis, Poststroke/CVA Hemiparesis
Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders
Activation is the amount of voluntary recruitment of a muscle during voluntary contraction. Full activation implies the recruitment of all muscle fibres at their tetanic frequency.
- Conditions
- Multiple Sclerosis, Poststroke/CVA Hemiparesis, Parkinson Disease, Knee Impairment
- Trial name
- ATTILA (NCT04607174)
- Testing
- Pathologic group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
PD, Gait Dysfunction, Neurologic
Effectiveness of Different Approaches for the Rehabilitation of Gait in Patients With Parkinson's Disease
Evaluation of the effectiveness of three different approaches for the rehabilitation of gait in patients with PD within a multidisciplinary, intensive rehabilitation treatment (MIRT).
- Conditions
- PD, Gait Dysfunction, Neurologic, Rehabilitation
- Trial name
- Tr-T-VR (NCT03021408)
- Testing
- MIRT + Treadmill, MIRT + Treadmill Plus, MIRT + Virtual Reality
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Dysphagia, Rehabilitation
Biofeedback as an Adjunctive Treatment for Post-stroke Dysphagia
The aim of the study is to evaluate whether the effect of biofeedback treatment is more effective than a control treatment in the recovery of dysphagia. This study will be a multicentric randomized, single-blind controlled study.
- Conditions
- Dysphagia, Rehabilitation, Stroke
- Trial name
- NCT05591040
- Testing
- Biofeedback, Conventional
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Spinal Cord Injury
Resistance Training and Testosterone After Spinal Cord Injury
The goal of this proposal is to investigate the efficacy of a complimentary approach of evoked resistance training and testosterone replacement therapy on the changes in body composition and metabolic profile after SCI.
- Trial name
- NCT01652040
- Testing
- Resistance Training and Testosterone Patches, Testosterone Patches
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- VA Office of Research and Development
Stroke
Evaluation of Whether Functional Strength Training Can Enhance Motor Recovery of the Upper Limb After Stroke
The purpose of this study is to test the hypothesis that adding functional strength training to UK conventional therapy improves muscle function and walking than either UK conventional therapy alone or increased intensity of UK…
- Trial name
- NCT00360789
- Testing
- Conventional UK physical therapy, Increased intensity of UK conventional physical therapy (PT), UK conventional PT plus functional strength training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- St George's, University of London
Stroke
A Randomized, Non-inferiority Clinical Trial of CVA Telerehabilitation Treatments - TelePhysioTaiChi
Telerehabilitation is a promising alternative approach that can help improve access to rehabilitation services once patients are discharged home after stroke.
- Trial name
- NCT01848080
- Testing
- Tai Chi based exercise program
- Where
- 3 sites in Canada
- Volunteers
- 142 people
- Sponsor
- Université de Sherbrooke
Cerebrovascular Accident (Stroke)
The Effect of an Inpatient Home-work Exercise Program on Leg Function After Stroke
This study would focus on a new method of adding extra leg homework exercises to the usual therapy delivered in the hospital. We propose to design an exercise program for the affected leg that would be given to the client as…
- Trial name
- NCT00908479
- Testing
- Leg Exercise Program, Leg Management group
- Where
- 5 sites in Canada
- Volunteers
- 142 people
- Sponsor
- University of British Columbia
Stroke, Spinal Cord Injuries
ZEPU-AI Series Limb Feedback Robot Training Study (ZEPUAISRCT)
The goal of this clinical trial is to learn whether robotic rehabilitation devices (ZEPU-AI2, AI4, AI6 Plus, and AI7A) are feasible, safe, and effective for adults with upper or lower limb motor problems.
- Conditions
- Stroke, Spinal Cord Injuries, Brain Injuries, Traumatic, Movement Disorder, Upper Extremity
- Trial name
- NCT07749625
- Testing
- ZEPU-AI2, ZEPU-AI4, ZEPU-AI6 Plus
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University