Clinical trials: Neurologic Signs
Chronic Pain
Developing a Tailored Psychosocial Education Intervention for Chronic Pain Management for Asian Americans
Chronic pain is a major population health issue affecting more than 100 million Americans and variations in chronic pain experiences have been widely documented, including differences in pain burden and likelihood of…
- Trial name
- NCT06725329
- Testing
- A tailored psychosocial education intervention
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- George Washington University
Telerehabilitation, Low Back Pain
Effect of Telerehabilitation Use in the Treatment of Non-specific Chronic Low Back Pain in the Brazilian Afrodescendants
The goal of this study is to measure the effect of telerehabilitation on the treatment of nonspecific chronic LBP in the adults Brazilian Black population. The main questions it aims to answer are: 1.
- Trial name
- NCT06443229
- Testing
- Graded Activity based in exercises and educational approach, Educational Approach
- Where
- Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Neck Pain
Sinew Acupuncture for Neck Pain: Randomized Controlled Trial
The study aims to examine the efficacy and safety of sinew acupuncture for chronic mechanical neck pain (CMNP).
- Trial name
- NCT02834702
- Testing
- Sinew acupuncture
- Volunteers
- 130 people
- Sponsor
- The University of Hong Kong
Chronic Nonspecific Low-back Pain
Efficacy of High-intensity Laser Acupuncture in Patients With Chronic, Non-specific Low Back Pain
The purpose of this study is to investigate the efficacy of high-intensity laser acupuncture on peak torque, power of trunk extensors and flexors, back pain, range of motion, function, and satisfaction in patients with chronic…
- Trial name
- NCT06260631
- Testing
- high-intensity laser acupuncture and Exercise therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Post-Surgical Complication, Breast Cancer Surgery
The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery
The goal of this clinical trial is to assess the efficacy of pentoxifylline in reducing postsurgical complications for breast cancer patients undergoing breast cancer surgery.
- Trial name
- NCT06087237
- Testing
- Pentoxifylline, paracetamol +ketorolac
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Mansoura University
Spinal Cord Injuries, Upper Extremity Paresis
Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries
Texas Biomedical Device Center at UT Dallas has developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury termed targeted plasticity therapy (TPT).
- Trial name
- NCT04288245
- Testing
- Active Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Cervicogenic Headache
Effects of Strain Counterstrain Versus Post Isometric Relaxation on Pain, Headache Frequency, and Quality of Life in Females With Cervicogenic Headache.
Cervicogenic headache is a secondary headache disorder associated with dysfunction of the cervical spine and surrounding muscles.
- Trial name
- SCS-PIR (NCT07897695)
- Testing
- Post Isometric Relaxation, Strain Counterstrain
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Qurat Ul Ain Ashfaq
Chronic Pain
Positive Psychology for Chronic Pain Self-management
Learning chronic pain self-management skills can help patients improve daily functioning and quality of life, while avoiding risks associated with opioids and other pharmacological treatments.
- Trial name
- NCT04321239
- Testing
- Positive STEPS
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Neurocognitive Deficit
Validation of MoCA-B and MoCA-Blind for Screening Cognitive Decline
The objective of this observational study is to assess the efficacy of two neuropsychological tests (MoCA-B and MoCA-Blind) in detecting cognitive decline in older adults.
- Trial name
- NCT07846839
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Low Muscle Strength, Malnutrition
Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care
The study aims to determine the effects of Oral Nutritional Supplement (ONS) added to usual care on body weight compared with usual care alone in community-dwelling adults aged 55 years and older who are at risk of malnutrition…
- Trial name
- NCT07753239
- Testing
- ONS, Standard of Care (SOC)
- Where
- 7 sites in Thailand
- Volunteers
- 304 people
- Sponsor
- Abbott Nutrition
Brain Injuries, Traumatic
Acute Intermittent Hypoxia in Traumatic Brain Injury
This study is designed to answer questions related to safety and preliminary efficacy of Acute Intermittent Hypoxia (AIH) in Traumatic Brain Injury (TBI) survivors.
- Trial name
- AIH (NCT04890639)
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Pain
Bioequivalence Study for Mejoral 500 Product
This will be a monocentric, single blinded, randomized, single-dose, two-periods, two-sequence, crossover bioequivalence study of two oral formulations in healthy participants under fasting conditions.
- Trial name
- NCT02504775
- Testing
- Mejoral® 500 Tablets, Tylenol® Caplets
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Post Operative Pain, Kidney Transplant; Complications
Post-surgical Chronic Pain After Retroperitoneal Laparoscopic Living Kidney Donor
This study aimed to determine the relationship between the quadratus lumborum and erector spinae plane block technique and the incidence and severity of chronic post-surgical pain in accordance with Brief Pain Inventory Score…
- Conditions
- Chronic Post Operative Pain, Kidney Transplant; Complications, Anesthesia Regional, Laparoscopy
- Trial name
- NCT05572775
- Testing
- Quadratus lumborum (QL) block, Erector Spinae Plane (ESP) Block
- Where
- Indonesia
- Volunteers
- 146 people
- Sponsor
- Universitas Indonesia
Chronic Pain, Cesarean Section Complications
Intra-epidermal Nerve Fibre Density and Its Relationship to Post-caesarean Section Pain
Chronic pain is a significant burden to the individual and society with post-surgical pain identified as a research priority for the speciality of anaesthesia.
- Trial name
- NCT03715075
- Testing
- Caesarean Section
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Pain
Does Alkalinization Reduce Perceived Pain Levels During Sentinel Lymph Node Imaging?
Pain during nuclear medicine breast lymphnode detection procedures has been reported as high as 8.8/10. Using Sodium Bicarbonate to alkalinize the radio-pharmaceutical injection, pain can safely be reduced from 6.6/10 to 4.7/10…
- Trial name
- buffering SLN (NCT01660412)
- Testing
- Standard of Care First, ph Altered first
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Arkansas
Diabetic Neuropathy, Painful; Diabetic Neuropathies
Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability
This is a 2-part study. In Part 1 of the study, subjects will undergo a pain reporting training program in which a painful stimulus will be applied to the subject's hand, and the subjects will be asked to report how painful the…
- Trial name
- NCT01928381
- Testing
- AZD5213 + pregabalin, pregabalin capsules
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Chronic Stable Angina
Pharmacokinetics of AUX-001 40mg Once-daily in Healthy Subjects Under Fasting and Fed Conditions
Exploratory, single-dose, open-label, pharmacokinetic study to establish uptake, plasma levels safety and tolerability of orally administered AUX-001 on an empty stomach (i.e, fasting) as well as after a meal (i.e.
- Trial name
- NCT06249581
- Testing
- AUX-001 40mg once-daily
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Auxilius Pharma sp.z.o.o.
Pain, Postoperative, Ketamine Adverse Reaction
Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
- Trial name
- NCT03525912
- Testing
- Ketamine
- Where
- Colombia
- Volunteers
- 101 people
- Sponsor
- Universidad de Antioquia
Low Back Pain
A Prospective Study of the InterFuse T(tm),
The purpose of this post-approval study is to demonstrate that the InterFuse T modular lumbar interbody device is at least equal in safety and efficacy to other (standard of care) TLIF devices.
- Trial name
- NCT02678130
- Testing
- InterFuse T, Standard of Care TLIF (Stryker AVS Unilif)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vertebral Technologies, Inc.
Parkinson's Disease, Tremor
Randomised Crossover Trial of DBS of Differential PSA Regions in Parkinson's Disease and Tremor
The posterior subthalamic area holds promise as a target region for deep brain stimulation in tremor and Parkinson's disease. Using the magnetic resonance-directed implantable guide tube surgical technique, subregions of the…
- Trial name
- NCT01945567
- Testing
- Up to 3 mA, 60 us, 130 Hz deep brain stimulation, Empirical unblinded deep brain stimulation programming
- Where
- Australia
- Volunteers
- 39 people
- Sponsor
- The University of Western Australia
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