Clinical trials: Neurologic Signs
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
The goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing percutaneous coronary intervention (PCI) for stable…
- Conditions
- Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris
- Trial name
- CEC-PPMI (NCT07848529)
- Testing
- Biomarker testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Baim Institute for Clinical Research
Ptosis, Eyelid
Efficacy of Aurosling in Frontalis Sling Suspension Surgery
To Study the Efficacy of Aurosling as a suspension material in Frontalis suspension surgery in ptosis
- Trial name
- NCT00753831
- Testing
- Aurosling
- Where
- India
- Volunteers
- 16 people
- Sponsor
- Aurolab
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Procedural Pain, Acute Pain
Fan-Assisted Local Cooling for Pain During Intravenous Cannulation in Adults
Inserting an intravenous (IV) cannula is one of the most frequently performed procedures in clinical practice, and it is commonly experienced as painful. Before the needle is inserted, the skin is routinely cleaned with alcohol.
- Conditions
- Procedural Pain, Acute Pain, Peripheral Intravenous Catheterization
- Trial name
- NCT07740837
- Testing
- Fan-assisted local cooling, Standard alcohol skin preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Antalya Health Sciences University
Epilepsy
Epilepsy Birth Control Registry
Despite the importance of birth control to women of reproductive age, there has been little formal investigation of the safety and effectiveness of birth control methods in women with epilepsy.
- Trial name
- EBCR (NCT01097837)
- Testing
- Non-interventional
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Neuroendocrine Associates P.C.
Chronic Obstructive Pulmonary Disease and Allied Conditions
Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?
This study aims to assess usual walking speed (4-metre gait speed) and markers of sarcopenia predict mortality in patients with chronic respiratory disease.
- Trial name
- NCT02261337
- Where
- United Kingdom
- Volunteers
- 565 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Post Operative Pain, Opioid Analgesic Adverse Reaction
Postoperative Analgesia Intervention With Non-opioid Alternatives (PAIN-Alt) Trial - Breast Surgery
North America is experiencing a crisis of opioid use and abuse, partially caused by excessive prescribing by doctors. People often receive their first opioid prescription for pain treatment after outpatient breast surgery (i.e.…
- Conditions
- Post Operative Pain, Opioid Analgesic Adverse Reaction, Surgery, Postoperative Pain
- Trial name
- PAIN-Alt (NCT06507345)
- Testing
- Opioid Analgesia (OA) [Multimodal analgesia including opioid drugs], Opioid-Free Analgesia (OFA) [Multimodal analgesia not including opioid drugs]
- Where
- Canada
- Volunteers
- 540 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Spinal Cord Associative Plasticity Study
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- SCAP (NCT05163639)
- Testing
- Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Columbia University
Symptomatic Lumbar Spinal Stenosis
Home-based Cycling for People With Lumbar Spinal Stenosis
The main objective of the study is to compare the efficacy on back-specific activity limitations at 4 months after-randomisation of home-based cycling using connected ergometric bicycles associated with usual care to usual care.
- Trial name
- FLEXCAL (NCT04075539)
- Testing
- Home-based cycling program, usual care
- Where
- France
- Volunteers
- 302 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hoarseness, Intubation
Rigid Video Stylet Vs Conventional Lightwand Intubation
Lightwand is a useful alternative device for intubation but scooping movement can induce damage and microbleeding of oral mucosa, postoperative hoarseness,sore throat.
- Conditions
- Hoarseness, Intubation, Sorethroat
- Trial name
- Optiscope (NCT02073786)
- Testing
- Conventional lightwand intubation, Rigid video stylet
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Spinal; Nerve Root, Pain, Pelvic Pain
Quality of Life and Pain Changes Due to DRG Stimulation for Chronic Pain
ACTIVE study- a prospective observational clinical study examining the changes in quality of life and pain following dorsal root ganglion stimulation for the treatment of chronic intractable pelvic and lower limb pain.
- Conditions
- Spinal; Nerve Root, Pain, Pelvic Pain, Regional Pain Syndrome, Chronic Pain Syndrome
- Trial name
- ACTIVE (NCT03417973)
- Testing
- dorsal root ganglion neuromodulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- KM Clinical Research Group
Phantom Limb Pain
Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response
The investigators have designed a pragmatic trial of home-based transcranial direct current stimulation (tDCS) for phantom limb pain (PLP), the PLP-EVEREST trial (PLP-EffectiVEness pRagmatic Stimulation Trial) to test a portable…
- Trial name
- PLP-EVEREST (NCT05188183)
- Testing
- M1 anodal home-based tDCS, Somatosensory Training, Usual Care
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Spaulding Rehabilitation Hospital
Chronic Pain
Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer Pain
this work is looking for comparison between the effect of tramadol versus morphine on PD1 and PD1-ligand in patients with chronic cancer pain
- Trial name
- NCT04589494
- Testing
- Tramadol Hydrochloride
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Postoperative Pain
Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration
The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.
- Trial name
- NCT04681222
- Testing
- LFCN, Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derince Training and Research Hospital
Breast Cancer, Circadian Rhythms
The Effects of Light Therapy to Treat Cancer-related Side Effects
Severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment.
- Conditions
- Breast Cancer, Circadian Rhythms, Fatigue, Sleep Disturbance
- Trial name
- NCT04418856
- Testing
- Light Glasses (Experimental), Light Glasses (Comparison)
- Where
- Iceland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Diabetes Mellitus (DM)
Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy
This research is structured as a cross-sectional observational study. The primary objective is to compare central sensitization across painful and painless phenotypes of diabetic peripheral neuropathy.
- Trial name
- NCT07316322
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post-operative Pain
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative Outcomes
Primary: To compare the post-operative pain in patients with neck extension and without neck extension. Secondary: To determine the benefit of neck exposure and peri-operative complications, which include duration of operation…
- Trial name
- NCT01620151
- Testing
- Extended neck with standard support or pillow
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Low Back Pain
The Effectiveness of Wet Cupping on Persistent Non-specific Low Back Pain
The hypothesis of this study is that the improvement of Numeric Rating Scale (NRS) for Pain at the end of the study will be greater in the Wet Cupping Treatment group than in the Waiting Control group.
- Trial name
- NCT00925951
- Testing
- Wet Cupping, Acetaminophen
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Korea Institute of Oriental Medicine
Cancer, Cancer Pain
Effect of Music on Pain and Anxiety in Palliative Cancer Patients
Background: Cancer patients receiving palliative care often endure a variety of distressing symptoms, most notably pain and anxiety.
- Conditions
- Cancer, Cancer Pain, Palliative Care, Anxiety
- Trial name
- NCT07262151
- Testing
- Music Application, Procedures for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Karamanoğlu Mehmetbey University
Hypogonadism, Male, Fatigue Syndrome, Chronic
Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone
The overall goal of this study is to evaluate the effect of a testosterone drug called Depo-Testosterone (or 'testosterone cypionate'), an FDA-approved drug for improving fatigue, sexual function, quality of life, body…
- Trial name
- NCT04049331
- Testing
- Testosterone Undecanoate 750 MG/3 ML Intramuscular Solution [AVEED]
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
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