Clinical trials: Neurologic Signs
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Chest Pain, Acute Coronary Syndrome
Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain
The ACUTE CT trial is designed to test whether the assessment of chest structures by high-resolution multislice computed tomography (CT) provides equivalent diagnostic accuracy for patient with acute chest pain or other potential…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
- Trial name
- ACUTE CT (NCT00855231)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Washington
Mastalgia
External Mastalgia-oil Versus Placebo in Premenopausal Women With Severe Mastalgia
This is a single-center, double-blind, randomized clinical trial to explore the efficacy and safety of external mastalgia-oil versus placebo in premenopausal women with severe mastalgia.
- Trial name
- NCT06966245
- Testing
- mastalgia-oil
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Prader-Willi Syndrome, Hypothalamic Obesity
Tirzepatide in PWS, HO and GNSO
This research study is comparing the effectiveness of a weight loss medication called Tirzepatide in young adults with Prader-Willi Syndrome and/or hypothalamic obesity, as compared to young adults with obesity that is unrelated…
- Conditions
- Prader-Willi Syndrome, Hypothalamic Obesity, Obesity/Therapy
- Trial name
- NCT06901245
- Testing
- Tirzepatide
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Grace Kim
Primary Dysmenorrhea
The Effect of Relaxation and Stretching Exercises on Pain and Quality of Life in Women With Primary Dysmenorrhea
The study aimed to examine the effect of stretching and relaxation exercises on pain and quality of life in women with primary dysmenorrhea.
- Trial name
- NCT05960695
- Testing
- Stretching, Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Low Back Pain
Manipulation Effects on Abdominal Muscles
The purpose of this study is to understand how different physical therapy interventions affect the use of certain abdominal muscles in patients with low back pain.
- Trial name
- NCT01745939
- Testing
- Lumbar Manipulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Schizophrenia
Staccato Loxapine in Agitation (Proof of Concept)
The purpose of this study is to assess efficacy and safety of Staccato Loxapine in the treatment of acute agitation in schizophrenic patients.
- Trial name
- NCT00369577
- Testing
- Inhaled Loxapine 5 mg, Inhaled Loxapine 10 mg
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alexza Pharmaceuticals, Inc.
Vasovagal Syncope, AV Block-2Nd Degree-Type 1
Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry
The CNA-FWRD Registry is an international prospective observational multicenter registry of patients with symptomatic vasovagal syncope and bradyarrhythmias managed under routine care by medical therapy and radiofrequency…
- Conditions
- Vasovagal Syncope, AV Block-2Nd Degree-Type 1, Sinus Pause
- Trial name
- CNA-FWRD (NCT06166277)
- Testing
- Ablation procedure
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Rush University Medical Center
Pain, Postpartum Depression
Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal tears. These tears can have a significant impact on women's quality of life in the short and long term.
- Trial name
- NCT03470675
- Testing
- Epidural saline + IV saline, Epidural morphine 3 mg + IV saline, Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Northwestern University
Sleep Disorders, HIV Infections
Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- Switch-ER (NCT00944957)
- Testing
- Raltegravir for the first 2 weeks, Efavirenz for the last 2 weeks, Efavirenz for the first 2 weeks
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation, Stroke
Minimally Invasive Surgical Treatment Versus Medical Management for Stroke Patients With Atrial Fibrillation
The purpose of this study is to compare a minimally invasive surgical procedure and medication management in stroke patients with Atrial Fibrillation.
- Trial name
- NCT01442181
- Testing
- Minimally Invasive Surgery, Medical therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Degenerative Joint Disease of Knee, Rheumatoid Arthritis
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Degenerative knee joint diseases are characterized by chronic pain, inflammation, and functional impairment. In these conditions, mast cell density in the synovial membrane is increased, resulting in an excessive release of…
- Trial name
- NCT07680101
- Testing
- Adelmidrol 2% / Hyaluronic Acid 1%, micronized Palmitoylethanolamide (mPEA) 300mg + ultramicronized Palmitoylethanolamide (umPEA) 600mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
Pain, Postoperative, Pain Prediction
Venous Cannulation Pain to Guide Choice of Anesthetic Method
The investigators have recently shown that pain associated with peripheral venous cannulation can be used to predict the risk of postoperative pain, where patients grading their pain associated with venous cannulation (VCP) above…
- Conditions
- Pain, Postoperative, Pain Prediction, Laparoscopic Surgery, Venous Cannulation Pain
- Trial name
- NCT04751812
- Testing
- High-pain multimodal anesthesia with opioids, Low-pain opioid free, Standard of care
- Where
- Sweden
- Volunteers
- 270 people
- Sponsor
- Region Halland
Suicide, Suicide, Attempted
Brief Cognitive Behavioral Therapy for People With Physical Disabilities
The purpose of this study is to examine the effectiveness of a psychotherapy (non-medication) treatment, Brief Cognitive Behavioral Therapy for Suicide Prevention, in reducing suicide ideation and attempts for people with…
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Disability Physical
- Trial name
- NCT05695430
- Testing
- Brief Cognitive Behavioral Therapy for People with Physical Disabilities
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University
Low Back Pain, Mechanical
Pain Education for Patients With Low Back Pain in Nepal: A Feasibility Study
The primary aim of this study is to evaluate the feasibility of a full randomized clinical trial for assessing the effects of pain education as an intervention for patients with LBP in a physiotherapy facility in Nepal.
- Trial name
- PEN-LBP (NCT03387228)
- Testing
- Pain education, Control group
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- Kathmandu University School of Medical Sciences
Stroke, Hemiplegia
CUped: An Approach to Motor Recovery Post-Stroke, Not Compensation
The goal of lower limb rehabilitation after stroke is recovery of independent walking at home and in the community. Few stroke survivors achieve this goal.
- Trial name
- NCT06329765
- Testing
- Exercise with CUped - a motor-assisted, split crank pedaling device and undergo 50 m of gait training.
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Marquette University
Stroke
Nutritional Status in Subacute Stroke Patients Under Rehabilitation
Recently, is becoming more evident a relationship between malnutrition, stroke-related sarcopenia and/or altered systemic oxidative status in patients with subacute stroke .
- Trial name
- Nutristroke (NCT04923165)
- Testing
- robotic assisted intervention, biochemical analyses, BIA, hand grip
- Where
- Italy
- Volunteers
- 119 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Equinus Deformity
Extracorporeal Shock Wave Therapy on Spastic Equinus Foot in Stroke Patients
The goal of this study is to evaluate long term effects of focused extracorporeal shock wave therapy (fESWT) on triceps surae spasticity in stroke patients according to the number of sessions applied.
- Conditions
- Stroke, Equinus Deformity, Spasticity, Muscle
- Trial name
- NCT06547684
- Testing
- fESWT
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Teresa Mateu Campos
Spinal Cord Injury, Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI (WINY)
This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT07222033
- Testing
- Hands-free exoskeleton
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Hearing Loss, Conductive, Hearing Loss, Mixed
Evaluating the Safety of BONEBRIDGE Implants in Children Under Five Years Old: This Study Looks at Children Under Five Who Got BONEBRIDGE BCI 602 Implants. It Collects Information on Any Problems With the Device or the Surgery to See if it is Safe Within the First Year After the Operation.
This study, titled "The BONEBRIDGE in Children Under Five: Premarket Clinical Investigation" (Study ID 2023BB006), looks at kids under five who have received the BONEBRIDGE BCI 602 hearing implant.
- Conditions
- Hearing Loss, Conductive, Hearing Loss, Mixed, Children Under 5 Years
- Trial name
- 2023BB006 (NCT06634784)
- Testing
- Bone Conduction Implant (BCI)
- Where
- 2 sites in Germany
- Volunteers
- 9 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
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