Clinical trials: Neurologic Signs
Sleep Deprivation, Aging
The Peripheral Blood Multi-Omics Study on Sleep Loss
Sleep plays a role in cognitive processes such as memory processing, attention processing, and overall cognitive function. In recent years, the bidirectional relationship between sleep loss and aging, as well as related…
- Conditions
- Sleep Deprivation, Aging, Alzheimer Disease, Healthy Lifestyle
- Trial name
- NCT06492109
- Testing
- Sleep manipulation
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Tinnitus, Anxiety
Mindfulness Based Tinnitus Reduction (MBTR): A Symptom Perception Shift Program
This study is a randomized, controlled trial of Mindfulness Based Tinnitus Reduction (MBTR) vs. Treatment As Usual (TAU). This study aims to determine patient's benefit from participating in an 8-week MBTR program as measured by…
- Conditions
- Tinnitus, Anxiety, Depression
- Trial name
- MBTR (NCT01229709)
- Testing
- Mindfulness Based Tinnitus Reduction
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Chronic Pain
Defense Health Agency- Development of a Medical Device Utilizing an EEG-Based Algorithm for the Objective Quantification of Pain
PainQx, with the support of the Department of Defense (Contract #W81XWH-21-C-0034), is conducting a study to collect electroencephalography (EEG) data from people with chronic pain in order to develop algorithms than will…
- Trial name
- PQXDOD1 (NCT05215184)
- Testing
- Zeto WR19 EEG Recording
- Where
- 5 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- PainQx, Inc
Analgesic Response
Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals
The aim of this study is to examine the effects of opioid analgesics on acute pain in participants maintained on buprenorphine+naloxone (Suboxone) for opioid use disorders.
- Trial name
- NCT02136784
- Testing
- morphine sulfate, hydrocodone, hydromorphone HCI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Los Angeles
Pain, Chronic Pain
Exploring the Feasibility of Using Virtual Reality as an Educational Tool in Chronic Pain Rehabilitation
Introduction: Chronic pain significantly impacts quality of life and requires comprehensive management strategies. Traditional pain education programs are beneficial but often require significant and prolonged patient engagement.
- Conditions
- Pain, Chronic Pain, Chronic Pain (Back / Neck), Adults
- Trial name
- NCT07434804
- Testing
- 6-Week Virtual reality-delivered pain science education and behavioural pain management program
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- University College Dublin
Pain, Acute Postoperative
Erector Spinae Plane Block Versus Thoracic Paravertebral Block in Laparoscopic Cholecystectomy
The study is planned as a single-center prospective randomized study and includes patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07149584
- Testing
- ESPB, TPVB, IV
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Weakness, Muscle, Muscle Weakness
Short Term Immobilization of the Lower Limb
The purpose of this study is to determine the effects of one week of knee-joint immobilization on muscle size, strength, neuromuscular function, and brain function.
- Conditions
- Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy
- Trial name
- STILL (NCT05072652)
- Testing
- Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Pain
Women's Mammography Study To Improve Comfort During Mammography
The purpose of this study is to determine in a randomized trial whether it is possible to decrease the discomfort of mammography by using the analgesic ibuprofen, or by using a scripted, supportive text informing patients about…
- Trial name
- NCT01716052
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Kenneth A. Kist,
Chronic Pain
Canadian Registry for the Use of Spectrum Therapeutics Cannabis Products in Subjects With Chronic Pain
Chronic pain affects at least 10% of the global population but is often poorly managed, given the variable efficacy of available pharmacological treatments and the limited accessibility of multidisciplinary interventions.
- Trial name
- NCT04763252
- Testing
- Spectrum Therapeutics cannabis products
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Canopy Growth Corporation
Hemorrhoids, Open Hemorrhoidectomy
Hemorrhoids: Options of Traditional Hemorrhoidectomy
The goal of this prospective clinical trial is to compare the outcomes of several technical options of open hemorrhoidectomy in patients with symptomatic hemorrhoids.
- Trial name
- NCT06132152
- Testing
- Open hemorrhoidectomy with 'cold' scalpel, Open hemorrhoidectomy with electrosurgical scalpel
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Center of Endourology "Endocenter"
Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia
Ride-On Toy Car Use During Operating Room Transfer in Preschool Children
The goal of this clinical trial is to determine whether the method of transfer to the operating room can reduce preoperative anxiety and postoperative emergence delirium in male children aged 3 to 7 years undergoing elective…
- Trial name
- NCT07403747
- Testing
- Toy car, Standard Transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Carpal Tunnel Syndrome
Effectiveness of Carpal Ligament Self-myofascial Stretching in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS), also known as median mononeuropathy, occurs when the median nerve is squeezed or compressed as it travels through the carpal tunnel at the wrist. It is common in the age group of 40-60 years.
- Trial name
- NCT06229249
- Testing
- Carpal ligament self-myofascial stretching, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Saud University
Parkinson Disease
The Impact of Three Distinct Exercise Types on Fatigue, Anxiety, and Depression in Parkinson's Disease
The purpose of the study is to learn about the impact of exercise on fatigue, anxiety, and depression in Parkinson's disease. It is well established that exercise improves the motor symptoms of Parkinson's disease.
- Trial name
- PDExercise (NCT03833349)
- Testing
- Spinning Class, Yoga Class, Dance Class
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Premier Health
Demyelinating Diseases of the Central Nervous System, Child
Core Stability, Functional Capacity, Balance, Strength, and Fatigue in Pediatric Demyelinating Diseases
This study aims to evaluate balance ability, core stability, functional capacity, lower extremity muscle strength, and fatigue levels in children diagnosed with central nervous system demyelinating diseases, in order to…
- Conditions
- Demyelinating Diseases of the Central Nervous System, Child, Core Stability, Balance
- Trial name
- PEDI-CORE (NCT07654738)
- Testing
- No ADT
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Covid-19
Recovery After Critical Covid-19 Infection
The study focuses on the recovery of respiratory, cardiovascular and neurological/neuropsychological recovery after intensive care treatment for covid-19.
- Trial name
- RECOVID (NCT04864938)
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Sleep Apnea, Obstructive
Study to Evaluate Recovery From Postoperative Pain After Sleep Apnea Surgery
The purpose of this study is to assess whether tonsillectomy and UPPP performed using the study device to treat Obstructive Sleep Apnea (OSA) symptoms in adults is associated with less postoperative pain during the 21-day…
- Trial name
- NCT00380458
- Testing
- Coblation (radiofrequency-based device)
- Where
- United States
- Sponsor
- ArthroCare Corporation
PTSD, Chronic Pain
TCI-Massage Clinical Trial
The goal of this hybrid implementation-effectiveness study is to learn about the effectiveness and appropriateness of "Trauma-Informed and Culturally-Responsive Integrated Massage Therapy" (TCI-Massage) for torture and war trauma…
- Conditions
- PTSD, Chronic Pain, Depression, Anxiety Disorders
- Trial name
- TCI-MT (NCT07482358)
- Testing
- TCI-Massage
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Center for Victims of Torture, United States
Pain
The Role of Opioidergic Systems in Breathing Based Analgesia
The purpose of this psychophysical and pharmacologic study is to determine if slow-breathing induced pain relief is mediated by endogenous opioids in response to intravenous (IV) administration of the opioid antagonist naloxone…
- Trial name
- NCT03419858
- Testing
- Mindfulness Meditation, Slow-Breathing, Naloxone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Postoperative Pain, Extubation Time
Impact of Parasternal and Rectointercostal Blocks on Extubation Time
"Postoperative pain constitutes a major recovery challenge in patients undergoing open-heart surgery with median sternotomy and chest tube insertion (subxiphoid/intercostal).
- Trial name
- NCT07916558
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Samsun University
Reproductive Health
Effects of Dry Heat Application for Menstrual Symptoms
This randomized controlled trial was to determine the effect of dry heat applied on foot base of the 65 nursing students on menstrual symptoms and pain.
- Trial name
- NCT05664048
- Testing
- Dry heat application
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
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