Clinical trials: Neurologic Signs
Gastrointestinal Hemorrhage
Assessment of Combined Bowel Preparation for Capsule Endoscopy Study
The investigators are conducting a study to see if taking a bowel preparation before having a capsule endoscopy is more helpful than the standard preparation of not eating after 7 PM the night before a capsule endoscopy in making…
- Trial name
- CEPREP (NCT01243736)
- Testing
- Combination Prep
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Tinnitus, Subjective, Vagus Nerve Stimulation
Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus
This clinical study is a prospective, multicenter, randomized, controlled, double-blind clinical study. Sun Yat Sen Memorial Hospital of Sun Yat sen University was the central unit, and Nanjing First Hospital, Sun Yat Sen…
- Conditions
- Tinnitus, Subjective, Vagus Nerve Stimulation, Music Therapy, Double-Blind Method
- Trial name
- NCT05417711
- Testing
- Transcutaneous Vagus Nerve Stimulation Paired with Tailor-Made Notched Music Therapy, Tailor-made Notched Music Training
- Volunteers
- 388 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cerebral Palsy
Effects of Associated Impairments on Activity and Participation in Children With Cerebral Palsy
This study will investigate the effects of associated impairments on the activity levels and social participation of school-aged children with Cerebral Palsy (aged 6-12) and their impact on their families' quality of life and…
- Trial name
- NCT06944171
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Hacettepe University
Neuralgia
The Effect of Soy Protein on Neuropathic Pain
Neuropathic pain is one form of chronic pain lacking effective pharmacotherapy. Interest in the role of complementary and alternative medicine is growing and diet is at the forefront of the search for alternative treatments for…
- Trial name
- NCT01050244
- Testing
- Whole soybean soymilk powder, Whole milk powder
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Dr. Yoram Shir
Acute Coronary Syndrome, Sleep Deprivation
Effects of Zolpidem CR® in Sleep and Heart Recovery in Cardiac Intensive Care Unit Patients
A double blind, randomized, placebo-controlled study will be conducted in cardiac ICU patients who had been diagnosed with acute coronary syndrome, using a sleep promoting drug (zolpidem controlled release).
- Trial name
- NCT01920334
- Testing
- Zolpidem CR 12.5mg
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Morbid Obesity, Hypertension
Prevention of Coronary Heart Disease in Morbidly Obese Patients
The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied.
- Conditions
- Morbid Obesity, Hypertension, Type 2 DM, Obstructive Sleep Apnea
- Trial name
- SphCor (NCT00626964)
- Testing
- Bariatric Surgery, Conservative Treatment:
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- The Hospital of Vestfold
Crohn's Disease
Efficacy and Safety of Oral OPS-2071 in Participants With Crohn's Disease Showing Symptoms of Active Inflammation
The purpose of this study is to evaluate the effects and safety of OPS-2071 (150, 300, or 600 mg twice a day [BID]) versus placebo, as add-on therapy in participants with Crohn's disease who show symptoms of active inflammation…
- Trial name
- NCT03850509
- Testing
- OPS-2071
- Where
- 31 sites in United States, Poland
- Volunteers
- 3 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Mechanical Low Back Pain
Comparison of the Effectiveness of Mat Pilates and Reformer Pilates in Women With Non-Specific Low Back Pain
In this study, the effects of instrumental pilates, mat pilates and general posture exercises on pain, disability, quality of life, flexibility and endurance of trunk extension muscles were researched in women with non-specific…
- Trial name
- NCT07134309
- Testing
- Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Obstructive Sleep Apnea, Snoring
Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study
This research study is being done to determine whether the repetition and resistance from the daily use of the myofunctional therapy (MT) nozzle will improve obstructive sleep apnea and primary snoring.
- Trial name
- NCT05371509
- Testing
- Myofunctional therapy (MT) nozzle
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Mayo Clinic
Neoplasms
Marijuana for Cancer Pain
To find out if it is safe and effective to use smoked marijuana in combination with opioids to treat cancer pain. The study will evaluate whether smoked marijuana, when used with opioids, will have an effect on pain relief, and…
- Trial name
- NCT00046709
- Testing
- Smoked Marijuana
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Center for Medicinal Cannabis Research
Gastroparesis
Study of Tadalafil for the Treatment of Diabetic Patients With Symptoms of Upset Stomach and Delayed Stomach Emptying
The purposes of this study are to determine whether an experimental drug known as tadalafil can reduce symptoms of dyspepsia (fullness after eating, inability to finish a regular meal, bloating, discomfort or pain in the upper…
- Trial name
- NCT00050609
- Testing
- tadalafil
- Where
- 12 sites in Canada
- Volunteers
- 2 people
- Sponsor
- Eli Lilly and Company
Temporomandibular Disorders (TMDs), Kinesiophobia
The Italian Version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD)
This observational, cross-sectional study aims to translate, culturally adapt, and psychometrically validate the Italian version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD-ITA).
- Trial name
- TSK-TMD-ITA (NCT07750509)
- Volunteers
- 250 people
- Sponsor
- Alessandro Aquino
Chronic Neck Pain
Qigong and Exercise for Neck Pain in Adults (QENA)
The purpose of this study is to assess the effectiveness of qigong for the treatment of chronic neck pain compared to exercise therapy and waiting list group.
- Trial name
- QENA (NCT00615732)
- Testing
- Qigong, exercise therapy
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- Charite University, Berlin, Germany
Post-Operative Confusion
High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery
This is a feasibility study to determine if enough patients undergoing elective or urgent cardiac surgery, can be enrolled in a study where patients are randomized to receive high spinal anesthesia as an adjunct to general…
- Trial name
- NCT05374356
- Testing
- Intrathecal bupivacaine and morphine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Laparoscopic Cholecystectomy, Acute Post-operative Pain
The Effect of Erector Spinae Block on Diaphragma Movement
Laparoscopic cholecystectomy surgeries cause moderate/severe pain and thus can result in shallow breathing, atelectasis and increased opioid consumption in the early postoperative period which in turn cause a longer hospital…
- Conditions
- Laparoscopic Cholecystectomy, Acute Post-operative Pain, Respiratory Diaphragm
- Trial name
- NCT05021822
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ufuk University
Orthodontic Discomfort, Pain, Orofacial
Comparison of Patient-reported Pain After Initial Archwire Placement
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective.
- Trial name
- Archwires (NCT03906422)
- Testing
- 3M Unitek 0.016 orthodontic archwire, Device: 0.016" Ormco 27oC NiTi orthodontic archwire, Device: 0.016" Ormco 35oC NiTi orthodontic archwire
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Disorders of Consciousness Due to Severe Brain Injury
Prognostication of Recovery in Early Disorders of Consciousness Study
By collecting multimodal metrics (e.g., clinical factors, neuroimaging, and EEG) in the early phase of severe brain injury (i.e., during the acute hospitalization when a patient has impaired consciousness), and measuring the…
- Trial name
- PREDICT (NCT04692922)
- Testing
- MRI, EEG
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Chronic Pain
Strategies to Improve Pain and Enjoy Life
In the Strategies to Improve Pain and Enjoy Life (STRIPE) study, the effectiveness of a multicomponent intervention will be tested, compared with usual care, on opioid dose and pain outcomes among patients on high dose (≥ 40 mg…
- Trial name
- STRIPE (NCT03743402)
- Testing
- Pain self-management training, video education, motivational interviewing, voluntary self-paced opioid taper
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- University of Washington
Spatial Neglect, Hemispatial Neglect
A Model to Identify Specific Predictors of Spatial Neglect Recovery
This study examines methods to better predict improvement of a hidden disability of functional vision, spatial neglect, following stroke.
- Conditions
- Spatial Neglect, Hemispatial Neglect, Hemineglect, Unilateral Neglect
- Trial name
- NCT00990353
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Kessler Foundation
Anesthesia, Pain
Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia
The aim of this prospective randomized study is to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in pediatric anesthesia.
- Conditions
- Anesthesia, Pain, Child
- Trial name
- NCT02683837
- Testing
- Remifentanil, Pupillometry, Sevoflurane
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
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