Clinical trials: Neurologic Signs
Postoperative Pain
Analgesic Efficacy of Erector Spinae Plane Block for Laparoscopic Inguinal Hernia Repair
Postoperative analgesia management in inguinal hernia surgery is difficult because of the content of the surgical procedure. A multimodal approach to postoperative analgesia has recently been proposed.
- Trial name
- NCT04131985
- Testing
- Erector Spina Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Stroke, Hemiplegia
Functional Electrical Stimulation for Footdrop in Hemiparesis
The objective of this research is to determine if electrical stimulation can improve the strength and coordination of the lower limb muscles, and the walking ability of stroke survivors.
- Trial name
- NCT00148343
- Testing
- Odstock Dropped-Foot Stimulator (ODFS), Conventional Standard of Care, Traditional Physical Therapy Treatment
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- MetroHealth Medical Center
Prostate Cancer, Castration Resistant Prostate Cancer
Study of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer
Bone metastases and associated pain are a major cause of morbidity and mortality in castration-resistant prostate cancer (CRPC).
- Conditions
- Prostate Cancer, Castration Resistant Prostate Cancer, Pain, Prostatic Neoplasms
- Trial name
- COMET-2 (NCT01522443)
- Testing
- cabozantinib, mitoxantrone, prednisone
- Where
- 82 sites in United States, Australia and 3 more
- Volunteers
- 119 people
- Sponsor
- Exelixis
Recurrence, Chronic Pain
10-year Results of Open Inguinal Hernia Repair
The main goal of the research is to evaluate the long-term results of open anterior alloplasty of inguinal hernia, mainly the occurrence of recurrences.
- Trial name
- NCT06008535
- Testing
- Open inguinal hernia repair
- Where
- Estonia
- Volunteers
- 234 people
- Sponsor
- Tartu University Hospital
Memory Impairment
Better Memory With Literacy Acquisition Later in Life
This study aims to discover whether acquiring basic-literacy in adulthood can improve episodic memory and brain structural and functional connectivity.
- Trial name
- NCT04473235
- Testing
- Literacy training, Non-Literacy training
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Spinal Cord Injury
Chronic Pain and Brain Activity in Spinal Cord Injury
This study compares five different procedures to see how they affect pain and brain activity. The procedures include neurofeedback, self-hypnosis training, meditation, and two different levels of transcranial direct current…
- Trial name
- NCT01012635
- Testing
- Hypnosis, Meditation, Neurofeedback training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
Postanesthetic Excitement, Cesarean Section
Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean…
- Trial name
- NCT06289335
- Testing
- saline solution
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Sleep Deprivation
Tips for Infant and Parent Sleep (TIPS)
A randomized controlled trial design will be used to answer whether a behavioral-educational sleep intervention and support from a nurse in the immediate postpartum improves maternal and infant sleep 6 weeks later.
- Trial name
- NCT00228215
- Testing
- TIPS Intervention
- Where
- 2 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Schizophrenic Disorders
Interest of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Auditory Hallucinations
Auditory hallucinations are common (present in 60-70% of cases) and extremely debilitating. Behavioral disorders associated with them can have serious social repercussions.
- Trial name
- TMS HALLU (NCT02525315)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Arteriovenous Fistula Dysfunction
Complementary Music Therapy for Pain During Percutaneous Transluminal Angioplasty.
This study evaluated the effectiveness of complementary music therapy in reducing pain among hemodialysis patients undergoing percutaneous transluminal angioplasty (PTA) for arteriovenous fistula dysfunction.
- Trial name
- NCT07766525
- Testing
- Complementary Music Therapy
- Where
- Taiwan
- Volunteers
- 114 people
- Sponsor
- Chang Gung Memorial Hospital
Central Nervous System Infections and Inflammations
Meningitis Encephalitis: a Metagenomics-Based Etiology & Epidemiology Research
Autoimmune encephalitis (AE) is caused by abnormal immune response mediated by autoimmune antibodies of patients, which can be detected by a serial of autoimmune antibodies[4,5,6,7].
- Trial name
- MEMBER (NCT04724876)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tongren Hospital
Pain, Cancer
Training of Arms to Reduce Pain With Peripheral Venous Catheter
Female patients undergoing chemotherapy for breast cancer often experience pain and discomfort when a peripheral venous catheter is inserted.
- Conditions
- Pain, Cancer, Veins
- Trial name
- NCT05716217
- Testing
- Arm training
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Vejle Hospital
Snoring, Mouth Breathing
Does myTAP Oral Appliance Therapy Including a Mouth Shield Lessen Periodontitis in Mouth-Breathers Who Snore?
Mouth breathing, snoring and poor sleep can contribute to and worsen periodontitis (gum disease). The purpose of this study is to test whether the myTAP oral appliance with a mouth shield (OA+) can lessen periodontal symptoms in…
- Conditions
- Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
- Trial name
- OAplusPerio (NCT06797089)
- Testing
- Oral appliance therapy plus scaling and root planing on left or right of mouth
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Neck Pain
Effect of Exercise Among Turtle Neck Syndrome in Pakistani Patients
Turtle neck also known as Text neck or anterior head syndrome is an overuse syndrome which occurs due to repetitive stress to neck, either by hanging it down or forward using phone or electronic devices.
- Trial name
- NCT05730868
- Testing
- myofascial release, muscle energy technique, MFR & MET
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- University of Karachi
Low Back Pain, Chronic Widespread Pain
13-year Follow-up of Women With Chronic Low Back Pain in Primary Care - a Prospective Longitudinal Cohort Study
Background: Low back pain (LBP) is among the main causes of long-term sickness absence and is associated with considerable costs for both the individual and society.
- Conditions
- Low Back Pain, Chronic Widespread Pain, Predictors, Pain
- Trial name
- NCT03974191
- Testing
- Change in function, activity, participation and other health related factors in CLBP and to identify predictors for pain, activity and work ability after 13 years.
- Where
- 3 sites in Sweden
- Volunteers
- 87 people
- Sponsor
- Vastra Gotaland Region
Sleep Disturbance, Sleep Wake Disorders
Improving Sleep Health in Adults With Overweight or Obesity
This study will examine the feasibility and acceptability of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) in adults with poor sleep and excess weight.
- Conditions
- Sleep Disturbance, Sleep Wake Disorders, Sleep Disorder
- Trial name
- NCT04990206
- Testing
- TranS-C
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension
Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents
There has been little research on neointimal coverage and malapposition after BES implantation using OCT in human coronary artery. Furthermore, specific drug may possibly influence the vascular healing after stent implantation.
- Trial name
- NCT01502904
- Testing
- Sirolimus-eluting stent, Biolimus-eluting stents, pravastatin 20mg/day after DES implantation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Neurologic Disorders, Nervous System Diseases
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will…
- Conditions
- Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders
- Trial name
- NEST (NCT02795052)
- Testing
- Intravenous and Intranasal BMSC
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Alzheimer Disease, Hearing Loss
Early Age-Related Hearing Loss Investigation (EARHLI)
Early Age-Related Hearing Loss Investigation (EARHLI) is a single site study that will randomize late middle age adults to either a hearing intervention (including hearing aids) or a health education intervention.
- Conditions
- Alzheimer Disease, Hearing Loss, Cognitive Impairment
- Trial name
- EARHLI (NCT06174038)
- Testing
- Hearing Intervention, Health Education Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Cataract, Retinal Edema
Prolensa (Bromfenac) 0.07% QD vs. Ilevro (Nepafenac) 0.3% QD for Treatment of Ocular Inflammation Post Cataract Surgery
To investigate inflammation, visual acuity and macular thickness after treatment with Prolensa vs Ilevro after cataract surgery.
- Conditions
- Cataract, Retinal Edema, Inflammation
- Trial name
- QD (NCT01847638)
- Testing
- Prolensa (bromfenac 0.07%), Ilevro (nepafenac 0.3%)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Melissa Toyos
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