Clinical trials: Neurologic Signs
Trigger Finger, Percutaneous A1 Pulley Release
Percutaneous Trigger Finger Release Concomitant Steroid Injection Versus Percutaneous Trigger Finger Release Alone
Background: Percutaneous A1 pulley release is a cost-effective and straightforward procedure with outcomes comparable to open A1 pulley release. Postoperative pain is a prevalent concern.
- Conditions
- Trigger Finger, Percutaneous A1 Pulley Release, Steroid Injection, Postoperative Pain
- Trial name
- NCT06288685
- Testing
- percutaneous A1 pulley release, Triamcinolone
- Where
- Thailand
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Police General Hospital, Thailand
Pain, Postoperative, Shoulder Pain
Interscalene Block Versus Costoclavicular Block for Shoulder Surgery
Interscalene brachial plexus block constitutes the analgesic criterion standard for shoulder surgery. However, it is associated with a high incidence of hemidiaphragmatic paralysis (HDP) that may not be tolerated by patients with…
- Conditions
- Pain, Postoperative, Shoulder Pain, Surgical Procedure, Unspecified, Diaphragmatic Paralysis
- Trial name
- NCT03411343
- Testing
- Interscalene Block, Costoclavicular Infraclavicular Block
- Where
- Chile
- Volunteers
- 44 people
- Sponsor
- University of Chile
Pain
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysteroscopy Practice
The purpose of this study is to demonstrate that Lidocaine-Prilocaine cream decrease pain during hysteroscopy diagnostic practice.
- Trial name
- HISTEROS-07 (NCT01094015)
- Testing
- lidocaine-prilocaine cream, gel application for the transmission of ultrasound
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Consorci Sanitari de Terrassa
Cleft Lip Palate, Orofacial Cleft
Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery
Orofacial clefts are among the most common congenital malformations, affecting approximately 1 in 700-1500 live births worldwide.
- Conditions
- Cleft Lip Palate, Orofacial Cleft, Agitation, Emergence, Analgesia Assessment
- Trial name
- NCT07557576
- Testing
- Ketamine (1 mg/kg), Dexmedetomidine (1-0,8-0,6-0,4 mcg/kg/h), Fentanyl 5 mcg/kg
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Iva Smiljanić
Chronic Pain, Opioid Use
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
This study is designed to find behavioral and neurophysiological correlates of pain avoidance behavior among chronic pain patients, controlling for risk for opioid use disorder.
- Trial name
- NCT04603417
- Testing
- Electroencephalography (EEG)/Magnetoencephalography (MEG)/MRI
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hearing Loss, Fatigue
Fatigue and Hearing Loss.
An intervention group and a control group will complete a battery of questionnaires at four time points to investigate the impact of first-ever hearing aid fitting on fatigue and associated variables.
- Trial name
- NCT04875117
- Testing
- Hearing aid
- Where
- 2 sites in United Kingdom
- Volunteers
- 129 people
- Sponsor
- University of Nottingham
Alzheimer Disease
REVEAL III: Risk Evaluation and Education for Alzheimer's Disease
The purpose of this study is to provide healthy adults with genetic testing and information about their chances of developing Alzheimer's disease.
- Trial name
- REVEAL (NCT00462917)
- Testing
- Pleiotropic info, in-person disclosure, AD-only info, in-person disclosure, Pleiotropic info, phone disclosure
- Where
- 4 sites in United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Bilateral Hearing Loss
Assessing Listening Effort at Different Signal-to-noise Ratios in Bone-anchored Users
The purpose of this study is to assess listening effort during a speech-in-noise task in bone-anchored hearing systems (BAHS) users via pupillometry.
- Trial name
- NCT04242940
- Testing
- Fitting of Ponto 4
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Oticon Medical
Pain
Vapocoolant Spray Used Prior to Intravenous (IV) Insertions
The primary purpose of this study is to determine if by offering a vapocoolant (cold spray) to hospital outpatients prior to an intravenous catheter (IV) insertion will increase patient satisfaction of IV insertion as well as…
- Trial name
- NCT03054740
- Testing
- Gebauer Ethyl Chloride, Nature's Tears
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aultman Health Foundation
Spinal Cord Injury (SCI), Neurogenic Bladder (NB)
Home Neuromodulation for Neurogenic Bladder Management in Spinal Cord Injury
The purpose of this study is to determine the safety and efficacy of Injectrode Tibial Nerve Stimulation for bladder function in people with spinal cord injury.
- Trial name
- NCT07264868
- Testing
- iTNS
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Pain
The Use of Resting State, fMRI and DTI in the Identification of Chronic Pain Conditions
Resting state fMRI scans of chronic pain sufferers will be compared to those of healthy normals and may be sufficiently different to allow a high level of classification accuracy of whether subjects have chronic pain.
- Trial name
- NCT02987933
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brain Scan Inc.
Seizure, Alcohol Related
Efficacy of Keppra in Acute Alcohol Related Seizure Control--A Pilot Study
Pilot study to evaluate efficacy of Keppra (levetiracetam) for seizure control in patients with alcohol related seizures.
- Trial name
- NCT00627133
- Testing
- levetiracetam
- Where
- United States
- Sponsor
- Medical University of South Carolina
Opioid-Related Disorders, Substance-Related Disorders
Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000252
- Testing
- 0% N2O, 10% N2O, 20% N2O
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis
A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in lumbar stenosis or spondylolisthesis patients with low back pain or sciatica at 3 locations of Jaseng…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Low Back Pain, Sciatica
- Trial name
- NCT03879447
- Testing
- Herbal medicine, Chuna manual medicine, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Jaseng Medical Foundation
Acute Pain
A Randomized Trial of Behavioral Economic Approaches to Reduce Unnecessary Opioid Prescribing
In this study, the investigators will evaluate the effect of a health system initiative aiming to change clinician opioid prescribing behaviors using two behavioral economic interventions - individual audit feedback and peer…
- Trial name
- REDUCE (NCT03825549)
- Testing
- Individual audit feedback, Peer comparison feedback
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pain
Osteopathic Medicine in the Management of Care-induced Pain in Elderly Care (OGéDIS)
The purpose of this study is to evaluate effects of Osteopathic Treatment in the Management of Care-induced pain in Elderly care, in Follow-up care and Rehabilitation Geriatric.
- Trial name
- OGéDIS (NCT02584049)
- Testing
- Osteopathy
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- Hôpital NOVO
Chronic Pain and Comorbid Emotional Problems
A Transdiagnostic Treatment for Comorbid Chronic Pain and Emotional Problems
The study uses a replicated randomized single case design. Participants were 12 individuals with chronic pain problems and residual problems after undergoing a multimodal pain rehabilitation.
- Trial name
- NCT02751749
- Testing
- Unified Protocol
- Volunteers
- 12 people
- Sponsor
- Örebro University, Sweden
Stroke, Cerebro-vascular Accident
Studying Fatigue and Movement After Stroke
The goal of this observational study is to learn how neuromuscular fatigue develops after stroke and how changes in brain activity, muscle activity, and their interaction contribute to reduced motor performance in stroke…
- Conditions
- Stroke, Cerebro-vascular Accident, Ischemia Stroke, Hemorrhage Stroke
- Trial name
- NCT07594938
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Spasms, Infantile, Epilepsy
Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment
OBJECTIVES: I. Evaluate the efficacy of surgical resection of an identifiable zone of cortical abnormality versus multiple drug therapy in children with infantile spasms refractory to standard therapy. II.
- Trial name
- NCT00004758
- Testing
- carbamazepine, corticotropin, nitrazepam
- Volunteers
- 30 people
- Sponsor
- National Center for Research Resources (NCRR)
Spinal Cord Infarction, Spinal Cord Stroke
Descriptive Study of Acute Spontaneous Spinal Cord Infarction
Acute spontaneous Spinal Cord Infarctions (SCI) are an uncommon cause of myelopathy (5%), but their prognostic is heterogeneous and frequently severe. Positive diagnosis is difficult, one quarter of initial MRIs are normal.
- Conditions
- Spinal Cord Infarction, Spinal Cord Stroke, Vascular Myelopathy
- Trial name
- EDMIAS (NCT04372758)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.