Clinical trials: Neurologic Signs
Dementia, Hearing Loss
Validation of Cognitive Screenings for the Hearing Impaired
There are currently no cognitive tests that have been validated as screening tools for people with dementia and comorbid hearing loss.
- Conditions
- Dementia, Hearing Loss, Auditory Processing Disorder
- Trial name
- NCT03648502
- Testing
- Cognitive tests and hearing tests
- Where
- 2 sites in United Kingdom
- Volunteers
- 78 people
- Sponsor
- University College, London
MPS II, Mucopolysaccharidosis II
MPS II Immunophenotyping
The purpose of this study is to investigate how participant's body's immune system responds to idursulfase, an enzyme replacement therapy (ERT) and find out which types of immune cells are involved in causing untoward responses…
- Conditions
- MPS II, Mucopolysaccharidosis II, Hunter Syndrome
- Trial name
- NCT04976231
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Intellectual Disabilities (F70-F79)
North Health in Intellectual Disability
Intellectual disability (ID) is a diagnosis characterized by significant limitations both in intellectual functioning and in adaptive behavior as expressed in conceptual, social and practical adaptive skills.
- Trial name
- NOHID (NCT03889002)
- Where
- Norway
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Delirium Risk, Critical Illness in Coronary ICU Patients
THE EFFECTS OF VIRTUAL ART THERAPY ON PHYSIOLOGICAL PARAMETERS, DELIRIUM RISK, ANGER, ANXIETY, AND MENTAL AND SPIRITUAL RECOVERY IN INTENSIVE CARE PATIENTS.
Patients in intensive care units experience significant physiological and psychological stress due to life-threatening conditions and invasive treatments.
- Conditions
- Delirium Risk, Critical Illness in Coronary ICU Patients, Mental and Spiritual Recovery, Effects of Virtual Art Therapy
- Trial name
- NCT07562802
- Testing
- Virtual Art Therapy
- Volunteers
- 62 people
- Sponsor
- Inonu University
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Malignant Solid Tumor, Pain
Pragmatic Research of Acupuncture and Counseling eXtended to Inpatient Services
Despite improved assessment and pharmacologic management, cancer pain is still undertreated. Using non-pharmacologic treatments alongside medications may better address patients' total pain experience by relieving physical and…
- Trial name
- PRACXIS (NCT03905720)
- Testing
- Acupuncture, Pain Counseling
- Where
- 2 sites in United States
- Volunteers
- 448 people
- Sponsor
- University of California, San Francisco
Postoperative Pain
US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy
To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External…
- Trial name
- NCT05272280
- Testing
- External oblique intercostal (EOI) block, Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pre - Delivery Pregnant Women, Chronic Pain
Assessment of Central Pain in the Peripartum Period
Chronic pain is common. Up to 10% of the Population has been estimated to suffer from chronic pain and up to 5% of the female population has been estimated to suffer from widespread, chronic pain and tenderness, thus fulfilling…
- Conditions
- Pre - Delivery Pregnant Women, Chronic Pain, Pain During Delivery
- Trial name
- NCT01291680
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Erector Spinae Block, Analgesia
Ultrasound Guided Bilateral Erector Spinae Block as Analgesia for Adolescent Idiopathic Scoliosis Correction
Scoliosis is a structural, tridimensional deformity of the spine. Characterized by lateral curvature and rotation of the vertebrae with functional limitations and cosmetic problems, idiopathic scoliosis, which accounts for 75% to…
- Conditions
- Erector Spinae Block, Analgesia, Scoliosis Idiopathic
- Trial name
- NCT04336046
- Testing
- erector spinae block, normal saline, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Low-level Laser Acupuncture in Patients With Total Knee Arthroplasty
Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:
Total knee arthroplasty is a common and effective surgical procedure for patients with end-stage knee osteoarthritis, and wound pain is still a problem for many of the patients.
- Trial name
- NCT03995446
- Testing
- low-level laser
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Cerebral Palsy, Spasticity
Power Wheelchair Joystick Use in Spastic Cerebral Palsy
There are over 750,000 individuals in the U.S. with Cerebral Palsy (CP). Up to 46% of adults with CP report limited mobility in their communities.
- Trial name
- NCT00337688
- Testing
- isometric joystick
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Intracerebral Hemorrhage
Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke
The goal of this clinical trial] is to determine if anakinra can ameliorate the formation of perihaematomal oedema in patients with spontaneous intracerebral haemorrhage (ICH).
- Trial name
- ACTION (NCT04834388)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Radboud University Medical Center
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Thoracic Outlet Syndrome
Electromyography in Thoracic Outlet Syndrome
Record the ENMG data carried out systematically in patients treated by rehabilitation for thoracic outlet syndrome in order to assess their characteristics and judge the relevance of these data in the context of the diagnosis and…
- Trial name
- ENMG-AFC (NCT05360303)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Nantes University Hospital
Shoulder Pain
Effectiveness of Pain Education Elderly Subacromial Pain
Objective: To verify the effectiveness of education in pain added to other treatment modalities (manual therapy and exercises) in the outcomes of pain, functionality, depression, anxiety, stress, kinesiophobia, self-efficacy and…
- Trial name
- Subacromial (NCT04941586)
- Testing
- Education in pain, Manual Therapy and Exercises, Manual Therapy and Exercises
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Rodrigo Gustavo da Silva Carvalho
Low Back Pain
Effects of Two Different Dry-Needling Techniques for Low Back Pain
Although dry-needling with or without manipulation has shown to be a useful technique to reduce pain in patients with low back pain (LBP), it is unclear which of these two dry-needling techniques would have a greater effect on…
- Trial name
- NCT03970486
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Brain Neoplasms, Malignant, Brain Neoplasms, Benign
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
RATIONALE: Pioglitazone hydrochloride may be effective treatment for cognitive dysfunction caused by radiation therapy. PURPOSE: This phase I trial is studying the side effects and best dose of pioglitazone hydrochloride in…
- Conditions
- Brain Neoplasms, Malignant, Brain Neoplasms, Benign, Malignant Meningioma, Glioblastoma Multiforme
- Trial name
- NCT01151670
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Rotating Frame Relaxation Imaging in Patients With Multiple Sclerosis
The aim of this study is to develop novel magnetic resonance imaging (MRI) protocols suitable for patients with multiple sclerosis using advanced MRI such as rotating frame relaxation imaging.
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Chronic Progressive
- Trial name
- ROMUS (NCT02403570)
- Testing
- Brain MRI
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- Turku University Hospital
Deep Breathing Maneuver, PROGRESSIVE MUSCLE RELAXATION EXERCISES
SHORT-TERM EFFECTS OF DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES ON MUSCULOSKELETAL PAIN AND WELL-BEING IN HIGH SCHOOL STUDENTS
Exam stress in high school students, long hours of studying in the static posture, and lack of physical activity habits can cause physical and psychological discomfort in them.
- Trial name
- Deep breathing (NCT06972173)
- Testing
- DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Reflex, Abnormal
Determination of Onset Point of Mechanical Stimulation
The difference between latencies of the tonic vibration reflex or T-reflex and whole body vibration-induced muscular reflex may be related to the distance between their stimulation point and the muscle spindles.
- Trial name
- TrueRL (NCT04347083)
- Testing
- Electrodiagnostic test
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
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