Clinical trials: Neurologic Signs
Postoperative Pain, Sternotomy Pain
Comparison of Erector Spinae Plane Block (ESPB) With the Combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) in the Management of Postoperative Sternotomy Pain in Patients Undergoing Cardiac Surgery Via Sternotomy
This study aims to compare the effectiveness of two regional anesthesia techniques in managing pain for participants undergoing cardiac surgery via sternotomy.
- Conditions
- Postoperative Pain, Sternotomy Pain, Acute Pain, Cardiac Surgery
- Trial name
- NCT07472296
- Testing
- Erector spinae plane block (ESPB), Superficial Parasternal Intercostal Plane Block (SPIPB), Serratus Anterior Plane Block (SAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Traumatic Brain Injury, Post-traumatic Stress Disorder
Improving Sleep in Veterans With the Polytrauma Clinical Triad
The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain.
- Conditions
- Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
- Trial name
- LIONv2 (NCT06477796)
- Testing
- Morning Bright Light Therapy, Negative Ion Generator
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Cerebrospinal Fluid Leak
The EVICEL® Neurosurgery Phase III Study
The objective of this study is to evaluate the safety and efficacy of EVICEL® Fibrin Sealant (Human) for use as an adjunct to sutured dural repair in cranial surgery.
- Trial name
- NCT02457546
- Testing
- EVICEL Fibrin Sealant, Hydrogel sealant
- Where
- 26 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Ethicon, Inc.
Aging, Foot Muscle Dysfunction
Effects of Rehabilitative Exergame Training on Foot Muscle Activity, Balance, and Mobility in Older Adults
This study is designed as a randomized controlled trial. A total of 40 healthy older adults residing in private and public nursing homes and rehabilitation centers in Mersin will be enrolled.
- Conditions
- Aging, Foot Muscle Dysfunction, Sarcopenia, Age-Related Muscle Weakness
- Trial name
- EXG-FOOT (NCT07357662)
- Testing
- Exergame-based Balance and Foot Muscle Training, Conventional Functional Balance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tarsus University
Hyperacusis
Role of Exposure in Hyperacusis
This study focuses on patients with a primary complaint of hyperacusis. Hyperacusis has been defined as 'abnormally reduced tolerance to sound'.
- Trial name
- NCT04705246
- Testing
- Psychoeducation
- Volunteers
- 5 people
- Sponsor
- University Hospital, Antwerp
COVID-19, Headache Disorders
Impact of COVID-19 Pandemic on Headache Evaluations in the Pediatric Emergency Department
Background: To evaluate the impact of COVID-19 on evaluations in the pediatric emergency department (ED) because of headache as main symptom.
- Conditions
- COVID-19, Headache Disorders, Emergency Service, Hospital
- Trial name
- NCT06295003
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Pain
Safety/Efficacy Study of Oxycodone HCl/Niacin to Treat Pain After Bunionectomy
The purpose of this study is to determine whether oxycodone HCl and niacin are effective in the treatment of pain following bunionectomy surgery.
- Trial name
- NCT00654069
- Testing
- Acurox 5/30 mg, Acurox 7.5/30
- Volunteers
- 405 people
- Sponsor
- Acura Pharmaceuticals Inc.
Bertolotti's Syndrome, Lower Back Pain
Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers
The purpose of this study is to collect lumbar rotations, velocity, and accelerations, along with pain scores using a novel dynamic VAS device, from twenty (20) Bertolotti Syndrome patients and twenty (20) non-Bertolotti low back…
- Trial name
- NCT06225583
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Ketamine-Induced Mood Disorder
The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
Optimal multimodal opioid-sparing analgesic technique is considered as one of the most important Enhanced recovery pathways (ERPs) or enhanced recovery after surgery (ERAS) interventions that mitigate the undesirable effects of…
- Trial name
- NCT05474183
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Pain
Effects of Simvastatin in the Prevention of Pain Experienced After Tooth Extraction
Atraumatic extraction of maxillary premolar teeth (on the Right, left side) was done; Subsequently, the patients were randomly divided into two equal groups: A group (Extraction + filled with a Simvastatin solution impregnated…
- Trial name
- NCT04406883
- Testing
- Extraction + filled with Simvastatin solution impregnated gelatin sponge
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Bell's Palsy
Mirror Therapy vs Mime Therapy in Bell's Palsy
This randomized controlled trial aims to compare the effectiveness of mirror book therapy and mime therapy in patients with Bell's palsy.
- Trial name
- NCT07716683
- Testing
- Mirror Book Therapy, Mime Therapy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- University of Lahore
Coronavirus Disease 2019
Neurologic Manifestations of COVID-19
This study will determine the neurological profile and predictors of outcomes in patients with COVID-19 disease in the Philippines.
- Trial name
- CORONA (NCT04386083)
- Where
- Philippines
- Volunteers
- 1,342 people
- Sponsor
- University of the Philippines
Low Back Pain, Tight Hip Muscles
Effects of Soft Ball Tissue Release Exercises on Low Back Pain Secondary to Tight Hip Muscles.
It is also suggested that low back pain patients tend to have trigger point or tight muscles, i.e. Gluteus Maximus, Gluteus Medius, iliopsoas and Quardatus Lumborum, on at least one side.After approval from the university ethical…
- Trial name
- NCT04815941
- Testing
- Soft ball tissue release exercises
- Where
- Pakistan
- Volunteers
- 23 people
- Sponsor
- Riphah International University
Hearing Loss
Evaluation of a New mHealth Tympanometer
Children in rural and underserved communities experience a disproportionately high burden of infection-related hearing loss, which is often preventable with timely identification and follow-up care.
- Trial name
- NCT05666505
- Testing
- Prototype mHealth tympanometer, Standard of care commercial tympanometer
- Volunteers
- 39 people
- Sponsor
- University of Arkansas
Gait Disorder, Sensorimotor
The Effects of Gait Performance and Brain Activity After Robot-assisted Gait Training (RAGT) On Patients With Lower Extremity Thermal Injury
Gait enables individuals to move forward and is considered a natural skill. Gait disturbances are very common in patients with burn injury. Major causes of gait disturbances are pain and joint contractures.
- Trial name
- NCT05988905
- Testing
- robot assited gati training, conventional traiing
- Volunteers
- 40 people
- Sponsor
- Hangang Sacred Heart Hospital
Post-Anoxic Coma, Postanoxic Enchephalopathie
Cracking Coma: Towards EEG and MRI Based Precision Medicine After Cardiac Arrest
Rationale: 30-70% of comatose patients admitted to the intensive care unit (ICU) after cardiac arrest never regain consciousness as a result of post anoxic encephalopathy (PAE).
- Trial name
- NCT03308305
- Where
- 3 sites in Netherlands
- Volunteers
- 94 people
- Sponsor
- Rijnstate Hospital
Anxiety, Pain
Heating Pad for in Office Cystoscopy and Urodynamic Testing
Patient frequently report experiencing discomfort associated with cystoscopy or urodynamic studies (UDS), and a small percentage of patients refuse these important procedures due to discomfort or fear of discomfort.
- Conditions
- Anxiety, Pain, Distress, Emotional
- Trial name
- NCT05981794
- Testing
- Electrical heating pad
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Angina, Stable, Angina, Unstable
Atherosclerotic Lesion Proteomics by Harvesting Angioplasty Balloons (ALPHA).
The purpose of the study is to identify proteins, metabolites and signal pathways related directly to symptomatic atherosclerosis and to disease progression.
- Conditions
- Angina, Stable, Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), ST-segment Elevation Myocardial Infarction (STEMI)
- Trial name
- NCT05319366
- Where
- 2 sites in Denmark
- Volunteers
- 225 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hemophilia A
Manual Therapy in Hemophilic Arthropathy of the Ankle
Introduction: Haemophilic ankle arthropathy manifests as functional (deficit in muscle strength, mobility and proprioception), intra-articular degenerative alterations and chronic pain.
- Trial name
- NCT06816056
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
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