Clinical trials: Neurologic Signs
Cognitive Neurodegenerative, Stroke
The Links Between Executive and Linguistic Processes and Their Lesional Determinants From a Verbal Fluency Task
Verbal fluency test require to produce as much words as possible in one or two minutes. This test is highly sensitive to main brain diseases and are therefore widely used in clinical routine for diagnostic purpose.
- Conditions
- Cognitive Neurodegenerative, Stroke, Verbal Fluency Disorders
- Trial name
- FluLEx (NCT05875103)
- Testing
- linguistic processes
- Where
- France
- Volunteers
- 302 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Syncope, Vasovagal
Midodrine and Fludrocortisone for Vasovagal Syncope
Syncope is a common condition which can disturb daily functions of the patients and impair their quality of lives. It contributes to 0.8 to 2.4% of the visits of emergency rooms.
- Trial name
- COMFORTS (NCT04595942)
- Testing
- Midodrine Hydrochloride Tablets, Fludrocortisone Acetate Tablets, Lifestyle modification
- Where
- Iran
- Volunteers
- 1,375 people
- Sponsor
- Tehran Heart Center
Stroke, Upper Extremity Paresis
Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients
To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.
- Conditions
- Stroke, Upper Extremity Paresis, Motor Activity
- Trial name
- NCT06397170
- Testing
- Graded repetitive arm supplementary program, Task based training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Pain, Stress
Evaluation Of The Analgesia Nociception Index vs. Surgical Pleth Index Under General And Regional Anaesthesia
There is a lack of sufficient analgesia monitoring apart from surrogate parameters. The analgesia nociception index (ANI) shall be evaluated under general and regional anaesthesia.
- Conditions
- Pain, Stress, Monitoring
- Trial name
- NCT02744573
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Postoperative Pain
Effect of Intravenous Acetaminophen on Postoperative Opioid-related Complications
Some patients have respiratory depression (decreased breaths per minute) after surgery. Acetaminophen, an FDA approved pain medication, may prevent this problem.
- Trial name
- NCT02156154
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Chronic Pain, Opioid Use
Improving Pain Disability With the Use of Oral Cannabinoids
The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain.
- Conditions
- Chronic Pain, Opioid Use, Cannabis
- Trial name
- NCT05351905
- Testing
- CBD oil ( MPL-001), CDB+THC oil (MPL-005)
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University Health Network, Toronto
Endometriosis, Pelvic Pain
Use of TENS Unit in the Management of Endometriosis Pain
The purpose of this study is see if Transcutaneous Electrical Nerve Stimulator (TENS) units help decrease endometriosis flare pain.
- Trial name
- NCT05348005
- Testing
- Ovira Transcutaneous Electrical Nerve Stimulation Unit
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Post-stroke Aphasia
Neurostimulation for the Treatment of Post-Stroke Aphasia
The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.
- Trial name
- NCT05194566
- Testing
- tACS
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- QVITI S.A.
Chronic Pain, Postoperative Pain
Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use
Patients with chronic pain syndrome (CPS) may develop central sensitization wich may lead to increased pain intensity and lower pain threshold sometimes to the extend of hyperalgesia and allodynia.
- Conditions
- Chronic Pain, Postoperative Pain, Central Sensitisation
- Trial name
- NCT05662566
- Testing
- Epidural replacement
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Eske Kvanner Aasvang
Renal Colic
Lornoxicam With Low Dose Ketamine Versus Pethidine to Control Pain of Acute Renal Colic
Patients with acute renal colic divided into 2 groups. Group L administered ornoxicam and Group P administered pethidine and VAS was recorded for both groups.
- Trial name
- NCT03780556
- Testing
- Lornoxicam and mepridine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cancer, Cancer Pain
Effect of Music on Pain and Anxiety in Palliative Cancer Patients
Background: Cancer patients receiving palliative care often endure a variety of distressing symptoms, most notably pain and anxiety.
- Conditions
- Cancer, Cancer Pain, Palliative Care, Anxiety
- Trial name
- NCT07262151
- Testing
- Music Application, Procedures for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Karamanoğlu Mehmetbey University
Cancer Pain
An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.
The purpose of this study is to compare of difference in NRS scores from baseline to the completion of treatment (5 days) in patients with administration of morphine sulfate versus oxycodone hydrochloride.
- Trial name
- SWITCH (NCT02660229)
- Testing
- Oxycodone Hydrochloride, Morphine Sulphate
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Mundipharma Korea Ltd
Breast Cancer, Quality of Life
Pilates and Dance to Breast Cancer Patients Undergoing Treatment
Breast cancer is one of the most common types of cancer in Brazil, and its treatment, namely surgery, chemotherapy, radiotherapy or hormone therapy, has consequences and side effects that significantly affect the quality of life…
- Conditions
- Breast Cancer, Quality of Life, Lymphedema, Fatigue
- Trial name
- NCT03194997
- Testing
- Dance, Pilates
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Laboratório de Pesquisa em Lazer e Atividade Física
Apraxia of Speech, Aphasia
A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes
In order to determine if speech-language therapy has positive effect, reliable measurement tools are required to document outcomes.
- Trial name
- NCT01979159
- Testing
- Combined Aphasia and Apraxia of Speech Treatment (CAAST)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Endometrial Cancer
Study of Post Operative Pain in Endometrial Cancer Robotic Versus Laparotomy
This study is being done to evaluate the efficacy of robotic approach for staging of endometrial cancer as compared to an equivalent abdominal approach.
- Trial name
- NCT00909896
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Supracondylar Fractures, Fracture Fixation
Animated Video and Associated Pain and Anxiety Reduction, Following Pin Removal Post-supracondylar Fracture Fixation
Assessing the reduction in pain and anxiety by the use of showing an animated video of the procedure, among pediatric patients undergoing pin removal after fixation of supracondylar fractures.
- Conditions
- Supracondylar Fractures, Fracture Fixation, Pain Severity, Anxiety
- Trial name
- NCT07234396
- Testing
- K-wire removal with animated procedure video being shown to the patient during its performance., K-wire removal without animated procedure video being shown to the patient during its performance.
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Liaquat National Hospital & Medical College
Dyslexia, Developmental
Neural Mechanisms of Successful Intervention in Children With Dyslexia
Dyslexia, an impairment in accurate or fluent word recognition, is the most common learning disability affecting roughly ten percent of children.
- Trial name
- NCT04323488
- Testing
- Lindamood-Bell Seeing Stars
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Glioma, Glioma (Diagnosis)
AI-driven Processing and Analysis of Glioma Imaging Data
GLIOMAID is a scientific research project focused on improving how brain tumors, specifically gliomas, are diagnosed and managed. It uses Artificial Intelligence (AI) to analyze MRI brain scans and patient data.
- Trial name
- GLIOMAID (NCT07703761)
- Testing
- AI-driven analysis of brain MRI data for early, non-invasive detection, segmentation, and histological characterization of gliomas using retrospective clinical and imaging records.
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Università degli Studi di Trento
Knee Osteoarthritis
Evaluation of the Evolution of Biological and Imaging Markers of Bone and Cartilage Degradation in Patients With Knee Osteoarthritis Receiving Intra-articular Injections of a Hyaluronan Derivative HYMOVIS®
This pilot study MOKHA is aimed to evaluate the beneficial effect of HYMOVIS® on cartilage of patients suffering of knee osteoarthritis as revealed by using scientifically sound, objective measurements of biological and MRI-based…
- Trial name
- MOKHA (NCT04293861)
- Testing
- HYMOVIS
- Where
- 8 sites in Belgium, France
- Volunteers
- 50 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Pain Treatment, Robotic Assisted Laparoscopic Surgery
Bilateral Dual Transversus Abdominis Plane Block for Robotic Assisted Laparoscopic Surgery
To evaluate the effects of bilateral dual transversus abdominis plane block on postoperative pain after robotic assited laparoskopic surgery and measure the plasma-level of ropivacain after the bilateral dual transversus…
- Conditions
- Pain Treatment, Robotic Assisted Laparoscopic Surgery, Bilateral Dual Transversus Abdominis Plane Block
- Trial name
- NCT01760161
- Testing
- Ropivacaine, Isotonic potassium chloride
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
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