Clinical trials: Neurologic Symptoms
Postoperative Pain
Adjuvant Analgesic Effects of Low Dose Tramadol/Acetaminophen Combination After Open Gynaecological Surgery
Patient experience moderate to severe pain after abdominal surgery. This post-operative pain can also contribute to complications such as respiratory impairment, cardiovascular events, ileus, sleep deprivation and mood…
- Trial name
- NCT00942565
- Testing
- tramadol/acetaminophen, acetaminophen
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Fibromyalgia
Thoracolumbar Fascia Thickness in Women With Fibromyalgia
This prospective cross-sectional observational study aims to compare thoracolumbar fascia thickness between women with fibromyalgia and healthy female controls using ultrasonography.
- Trial name
- FMS (NCT07839065)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Hearing Loss, Sensorineural, Hearing Impairment, Sensorineural
A Study Protocol for the Validation of UAud in a Clinical Setting.
The objective of this study is to validate the User-operated Audiometry (UAud) system for user-operated audiometry in a clinical setting, by investigating if hearing rehabilitation based on UAud is non-inferior to hearing…
- Trial name
- NCT05043207
- Testing
- uAud, Traditional audiometry
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Asymptomatic Condition, Neck Pain
Accessory Movements and Associated Factors During Active Cervical Range of Motion
This project aims to quantify accessory movements that occur during cervical range of motion (ROM) assessment in young adults and to examine their relationship with functional and psychological factors.
- Trial name
- NCT07267507
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Atılım University
Pain
Comparison of Exparel to Bupivacaine With Dexamethasone in TAP Block
The purpose of this study is to compare the efficacy and duration of bupivacaine extended-release liposome injection (Exparel) versus bupivacaine with dexamethasone in transversus abdominis plane (TAP) blocks for patients…
- Trial name
- TapBlock (NCT02179892)
- Testing
- Bupivacaine Extended-Release Liposome Injection (Exparel), Bupivacaine and Dexamethasone Injection, IV Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Colette Curtis MD
Shoulder Pain
Physical Performance and 3D Shoulder Kinematics of Asymptomatic Unilateral/Bilateral Overhead Athletes and Non-athletes
This study compares the performance and 3-dimensional shoulder kinematics between sides in unilateral overhead-throwers (volleyball attackers), bilateral overhead athletes (swimmers) and non-athletes during two physical…
- Trial name
- NCT02852707
- Testing
- Chronic exposure to unilateral overhead sports activity, Chronic exposure to bilateral overhead sports activity, Not exposed
- Where
- 3 sites in Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Ototoxicity
Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment
The purpose of this study is to evaluate whether DB-020 administered via an injection in the middle ear prevents hearing loss in participants who will receive high doses of cisplatin as part of their treatment for cancer.
- Trial name
- NCT04262336
- Testing
- DB-020
- Where
- 8 sites in United States, Australia
- Volunteers
- 22 people
- Sponsor
- Decibel Therapeutics
Subarachnoid Hemorrhage (SAH), Tachycardia
Impact of Tachycardia on Outcome After Subarachnoid Hemorrhage (SAH)
The purpose of this retrospective study is to test the hypothesis that uncontrolled tachycardia serves as a risk factor for adverse cardiovascular events and poor outcome after Subarachnoid Hemorrhage (SAH).
- Trial name
- NCT01585311
- Where
- United States
- Volunteers
- 1,540 people
- Sponsor
- Columbia University
Postoperative Pain
Comparison of Analgesic Effects of TAP Block and RSB in RALPs
In this research, we aim to compare the postoperative analgesic efficacy of these two peripheral blocks in patients undergoing RALP who have received preoperative TAP block and RSB block.
- Trial name
- NCT06681571
- Testing
- TAP Block, RSB
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Pain, Pharmacokinetics
Clinical Study in Healthy Men to Investigate the Uptake of Buprenorphine and Its Elimination From the Body After Dermal Application as Patches for 96 Hours and for 72 Hours
The purpose of the study was to investigate the pharmacokinetics (i.e. the uptake, distribution and elimination from the body) of dermally applied buprenorphine during and after different application periods, i.e., a 96-hour and…
- Trial name
- NCT03770234
- Testing
- Transtec 35 µg/hour transdermal patch
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Diaphragmatic Paralysis
Interscalene Block and Dysfunction Diaphragmatic
The study seeks to show that interscalene injection of a small volume (<8ml) of ropivacaine at a low concentration (0.1%) reduces the frequency of hemi-diaphragmatic paresis compared to low volume injection at the standard…
- Trial name
- NUMEROBIS (NCT04173364)
- Testing
- Ropivacaine 0.5% Injectable Solution, Ropivacaine 0.1% Injectable Solution
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Lille
Severe Stroke, Acute Stroke
Efficacy of End-Effector Robot-Assisted Gait Training in Subacute Stroke Patients
To date, no studies seems to compare conventional gait rehabilitation program with end-effector RAGT in subacute stroke patients by analysing the variations of gait kinematics beyond clinical multi prospective outcomes.
- Conditions
- Severe Stroke, Acute Stroke, Mild Stroke, Central Nervous System Diseases
- Trial name
- NCT03805009
- Testing
- Robot-Assisted Gait Training (RAGT)
- Where
- 2 sites in Italy
- Volunteers
- 26 people
- Sponsor
- IRCCS San Raffaele Roma
Opioid Use, Unspecified, Bariatric Surgery Candidate
Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids
The goal of this clinical trial is to compare Opioid Free and Opioid Based Anaesthesia in patients undergoing sleeve gastrectomy.
- Trial name
- NCT05752799
- Testing
- Opioid Free Anaesthesia, Opioid based anesthesia
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Peripheral Arterial Disease
Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies
Intermittent claudication afflicts 5% of the US population older than 55 years of age and develops along with hardening of the arteries of the legs.
- Trial name
- NCT01970332
- Testing
- Revascularization Surgery, Supervised exercise therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Nebraska
Lumbar Disc Herniation, Radiculopathy Lumbar
Efficacy and Safety of Electroacupuncture on Lumbar Disc Herniation with Radiculopathy
Lumbar disc herniation with radiculopathy (LDHR) is the local displacement of the intervertebral disc and its contents beyond the edge of the normal intervertebral disc space, resulting in pain, weakness or numbness in the muscle…
- Trial name
- NCT06611332
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Joint Pain, Chronic Pain
Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty
Personalized medicine is a concept in which medical care is individualized to a patient based on their unique characteristics, including comorbidities, demographics, genetics, and microbiome.
- Conditions
- Joint Pain, Chronic Pain, Opioid Use
- Trial name
- NCT04974463
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of California, San Diego
Cerebral Palsy, Muscle Hypertonia
Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in Child
In children requiring botulinum toxin injections, improving supervisory procedures of injection sessions to reduce pain and improve the experience of this invasive procedure is needed.
- Trial name
- CLOWN-TOX (NCT03149263)
- Testing
- distraction
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Hematoma, Subdural, Chronic
Exhaustive Drainage Versus Fixed-time Drainage for Chronic Subdural Hematoma After One-burr Hole Craniostomy
A prospective, multicenter, randomized controlled trial is designed to compare the recurrence rates and clinical outcomes in patients with chronic subdural hematoma using exhaustive drainage or fixed-time drainage after one-burr…
- Trial name
- ECHO (NCT04573387)
- Testing
- Operation, Fixed-time drainage, Exhaustive drainage
- Where
- 17 sites in China
- Volunteers
- 309 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Nocebo Effect
Muscle Synergies in Pain and Pain Anticipation
This study investigates how the anticipation of pain affects muscle synergies. One group will be recruited who will first experience actual pain from capsaicin cream and are then presented with a harmless cream deceptively…
- Conditions
- Pain, Nocebo Effect, Pain Anticipation
- Trial name
- NCT07251387
- Testing
- Pain expectation conditioning, Gait assesment
- Where
- 2 sites in Canada, France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universite de Picardie Jules Verne
Oxygen Metabolism, Muscle Spasticity
Hemodynamic Changes During Dry Cupping Therapy on Low Back Pain
This study aims to investigate the hemodynamic changes during dry cupping therapy (DCT) on low back pain. 50 patients with low back pain as experimental group and 50 healthy people as control group are treated by DCT.
- Trial name
- NCT03816787
- Testing
- Negative pressure therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
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