Clinical trials: Neurologic Symptoms
Chronic Nonspecific Low Back Pain, Low Back Pain
Therapeutic Exercise and Therapeutic Patient Education With or Without Manual Therapy for Chronic Nonspecific Low Back Pain.
This clinical trial study evaluates the effectiveness of a multimodal physiotherapy treatment based on a biobehavioural paradigm in the treatment of non-specific chronic low back pain.
- Trial name
- NCT03181659
- Testing
- Manual Therapy, Therapeutic Education, Therapeutic Exercice, Therapeutic Education, Therapeutic Exercice
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Roy La Touche Arbizu
Depressed Mood, Young Adults
Heat and Mental Health - PART 2
The goal of this clinical trial is to learn how hot indoor temperatures affect mood in young adults with depression, with or without anxiety.
- Conditions
- Depressed Mood, Young Adults, Heat Stress, Sleep
- Trial name
- NCT07903896
- Testing
- Heat/Humidity Exposure Condition, Thermoneutral Condition
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Hartford Hospital
Pain
Influence of Patient Choice of Intrathecal Morphine on Post-cesarean Delivery Pain.
This is a randomized controlled study that will place patients into a "choice" and a "no choice" group. The choice group will be able to choose between receiving 100 mcg or 200 mcg intrathecal morphine.
- Trial name
- NCT01425762
- Testing
- Drug Dose
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Stanford University
Neuropathic Pain
Non Invasive Brain Evaluation and Treatment for Neuropathic Pain
This trial is designed to preliminary evaluate the efficacy and safety of NIBS system for evaluation and treatment of neuropathic pain.
- Trial name
- NIBSNP (NCT02740062)
- Testing
- NIBS system for evaluation and non invasive current stimulation
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- NIBS NeuroScience Technologies
Machado-Joseph Disease
Weight in Lower Limbs Improves Gait Ataxia of in Machado-Joseph Disease Patients
Few studies evaluated the efficacy of adding weights on the lower limbs in patients with ataxic disorders. There is no current evidence on which would be the most appropriate weight for use in this context.
- Trial name
- NCT02906046
- Testing
- Weight in Lower Limbs
- Volunteers
- 20 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Spinal Cord Injuries, Neuropathic Pain
Evaluation of Initiation Time on the Efficacy of Gabapentin in Treating Neuropathic Pain in SCI
Neuropathic pain is a common complaint in those with spinal cord injury (SCI) that has a significant negative effect on quality of life. Efficacy of various treatments, however, remains controversial.
- Trial name
- NCT04256603
- Testing
- Gabapentin, No gabapentin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- MetroHealth Medical Center
Hip Fractures, Analgesia
Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block
The investigators propose to investigate the effect of intraoperative FICB and intrafragmentary fracture blockade on postoperative pain and opiate consumption using a randomized controlled trial study design.
- Conditions
- Hip Fractures, Analgesia, Opioid Use, Pain, Postoperative
- Trial name
- NCT04335461
- Testing
- Cephalomedullary nailing of extracapsular hip fracture, cephalomedullary nail, Regional Anesthetics
- Where
- United States
- Sponsor
- Montefiore Medical Center
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Persistent Ductus Arteriosus, Complication of Prematurity
The Preterm Infants' Paracetamol Study
Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants.
- Conditions
- Persistent Ductus Arteriosus, Complication of Prematurity, Pain or Discomfort in Intensive Care of Preterm Infants
- Trial name
- PreParaS (NCT01938261)
- Testing
- paracetamol, 0.45 % saline solution
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Cheyne-Stokes Respiration, Sleep Apnea, Central
Bipap Automatic Servo Ventilation (autoSV) Advanced in Central Apnea Patients
Pilot study testing the Bipap autoSV Advanced Algorithm during full night, in-lab polysomnography (PSG) and 3 months at home on patients with Central Sleep Apnea, Hunter Cheyne Stokes Respiration, or Complex Sleep Apnea.
- Trial name
- NCT01199042
- Testing
- BiPAP autoSV Advanced
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Philips Respironics
Gastrointestinal Malignancy, Pain Control
The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)
This study will target patients with gastrointestinal (GI) malignancy who present to any of 4 Penn Medicine emergency departments (EDs) with intractable abdominal pain.
- Trial name
- EGIPT (NCT07211386)
- Testing
- Erector Spinae Plane Block
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Low Back Pain, Back Pain
KLOS Study - Korean Medicine Registry for Low Back Pain Patients, a Prospective, Observational, Multicenter, Pilot Study
The Purpose of this trial is to define the characteristics of the in/outpatients with low back pain in traditional Korean medicine rehabilitation clinic.
- Conditions
- Low Back Pain, Back Pain, Pain, Neurologic Manifestations
- Trial name
- KLOS (NCT02418286)
- Testing
- expose to any drugs or procedures based on traditional Korean medicine theory
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gachon University Gil Oriental Medical Hospital
Osteo Arthritis Knee, Pain, Chronic
Platelet Rich Plasma Versus Radio Frequency for Chronic Knee Arthritis
Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities.
- Trial name
- NCT03886142
- Testing
- radiofrequency, platelet rich plasma injection
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Breast Neoplasm Female, Symptom Cluster
Effects of a Traditional Chinese Exercise Program on Symptom Cluster in Breast Cancer Patients
The Medical Research Council Framework for Developing and Evaluating Complex Interventions (MRC Framework) will be utilized to develop and evaluate an evidence-based tai chi intervention for managing the symptom cluster of…
- Conditions
- Breast Neoplasm Female, Symptom Cluster, Tai ji
- Trial name
- NCT04190342
- Testing
- control group, tai chi group
- Where
- 2 sites in China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Neuropathic Pain
Methylene Blue Intravenously and Chronic Neuropathic Pain
Aim of Investigation Methylene blue (MB) is a diaminophenothiazine with antioxidant, anti-inflammatory properties and with inhibitory effects on nitric oxide.
- Trial name
- NCT02303886
- Testing
- Methylene blue
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Relapsing-Remitting Multiple Sclerosis
BG00012 Monotherapy Safety and Efficacy Extension Study in Multiple Sclerosis (MS)
The primary objective of this study is to evaluate the long-term safety profile of BG00012 (dimethyl fumarate). Secondary objectives of this study are to evaluate the long-term efficacy of BG00012 using clinical endpoints and…
- Trial name
- ENDORSE (NCT00835770)
- Testing
- dimethyl fumarate
- Where
- 246 sites in United States, Australia and 32 more
- Volunteers
- 1,736 people
- Sponsor
- Biogen
Coronary Artery Disease
Safety and Efficacy Study of PB127 Ultrasound Contrast Agent in Patients With Suspected Coronary Artery Disease 007
This trial is to compare PB127 echocardiography to other heart imaging studies.
- Trial name
- NCT00595673
- Testing
- PB127 for injectable suspension
- Where
- 19 sites in United States
- Volunteers
- 428 people
- Sponsor
- Point Biomedical
Anxiety, Pain
Using a Stress Ball With Music During Colonoscopy
This study aims to evaluate whether using a stress ball together with listening to music during a colonoscopy procedure can reduce patients' pain and anxiety and improve their overall experience of the procedure.
- Conditions
- Anxiety, Pain, Colonoscopy
- Trial name
- NCT07590869
- Testing
- Music and Stress Ball Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Pain
Comparative Bioavailability Study of Morphine Sulfate Immediate Release and Controlled Release
Characterize the steady-state pharmacokinetics of morphine after oral administration of Roxane Laboratories' morphine sulfate immediate release tablets and oral solution and to compare their pharmacokinetics to that of AVINZA.
- Trial name
- NCT00994383
- Testing
- morphine sulfate
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms)
tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety
This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat.
- Conditions
- Healthy Participants, Anxiety Disorders (With High Anxiety Symptoms), Depressive Disorders (With High Anhedonia Symptoms), Comorbid Depression and Anxiety Disorder (With High Anhedonia and High Anxiety Symptoms)
- Trial name
- NCT07476469
- Testing
- tVNS
- Where
- Germany
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dr. Nils B. Kroemer
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