Clinical trials: Neurologic Symptoms
Parkinson's Disease, Foot Dystonia
Foot Dystonia Treatment by Botulinum Toxin Injections in Parkinson Disease : Efficiency of Injections Made in Extrinsic Muscle (Flexor Digitorum Longus Muscle) Compared to Intrinsic Muscle (Flexor Digitorum Brevis or Quadratus Plantae Muscles)
Foot dystonia is frequently observed in patients suffering from Parkinson'disease. It is characterized by an abnormal involuntary movement which is very uncomfortable (difficult to walk) and painful for the patient.
- Trial name
- RBHP 2008 (NCT00909883)
- Testing
- Botulinum Toxin: Xeomin
- Where
- 4 sites in France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Menorrhagia, Pelvic Pain
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic Hysterectomy
Robotic-assisted surgery is becoming more prominent within the specialty of Gynecologic surgery with little direct evidence that it is if not better than traditional laparoscopic surgery, at least equivalent.
- Conditions
- Menorrhagia, Pelvic Pain, Hysterectomy
- Trial name
- NCT02118974
- Testing
- Hysterectomy
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Milton S. Hershey Medical Center
Taste, Altered
Fatty Acid Taste Rating With or Without Sour Taste Adaptation
We are trying to figure out whether the fatty acid taste is differentiated from sour taste.
- Trial name
- NCT04248374
- Testing
- Taste Intensity
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Purdue University
Neurologic Deficits
NeuroVision vs Standard Neuromonitoring
The purpose of this study is to perform a prospective, randomized, controlled clinical trial to assess the utility of IONM in patients undergoing primary, single or multilevel lateral spinal procedures.
- Trial name
- NCT04639297
- Testing
- NeuroVision® IONM, Hospital Based IONM
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Postoperative Pain
The Median Effective Dose (ED50) of Paracetamol and Morphine : A Study of Interaction Study
The aim of our study is to define the median effective analgesic doses (ED50) of paracetamol, morphine, and their combination and determination the nature of their interaction administered IV for postoperative pain after moderate…
- Trial name
- NCT01366313
- Testing
- Paracetamol, Morphine, Paracetamol- Morphine
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Procare Riaya Hospital
Pain, Psychosocial Effects of Cancer and Its Treatment
Reflexology or Aromatherapy Massage in Relieving Symptoms in Patients With Cancer
RATIONALE: Reflexology and aromatherapy massage may lessen symptoms in patients with cancer. It is not yet known whether reflexology is more effective than aromatherapy massage in relieving symptoms in patients with cancer.
- Conditions
- Pain, Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01217424
- Testing
- questionnaire administration, aromatherapy and essential oils, management of therapy complications
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Multiple Sclerosis, Optic Neuritis, Demyelinating Disease
Visual (Path)Ways in Multiple Sclerosis - Part II
Multiple sclerosis (MS) is an inflammatory demyelinating and degenerative disease of the central nervous system. The mechanisms of neuro-axonal loss remain incompletely elucidated.
- Trial name
- VWIMS - II (NCT06776224)
- Testing
- Measurement of retinal vascular density and visual cognition
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Lille
Depression, Postpartum
CODEPAD-III (Collaborative Outcomes of DEpression and Pain Associated With Delivery-III)
The childbirth process is associated with increased risk of having depression and persistent pain which may have adverse effects to mothers and their babies.
- Conditions
- Depression, Postpartum, Pain, Mental Health
- Trial name
- CODEPAD-III (NCT07773259)
- Testing
- Collaborative Psychological Model (CPM), Intervention common to both arms, Telephone-based support (Control)
- Volunteers
- 3,470 people
- Sponsor
- KK Women's and Children's Hospital
Sarcopenia, Osteopenia or Osteoporosis
Pilot Study On Pulsed Electromagnetic Field Therapy For Osteosarcopenia
This prospective, single-site, single arm pilot study aims to assess the efficacy of Pulsed Electromagnetic Field (PEMF) exposure in the reduction of the decline in muscle strength, function and bone mineral density (BMD) in…
- Trial name
- NCT05043480
- Testing
- PEMF
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Louis Tee
Parkinson's Disease, Essential Tremor
Deep Brain Stimulation Surgery for Movement Disorders
Background: Deep brain stimulation (DBS) is an approved surgery for certain movement disorders, like Parkinson's disease, that do not respond well to other treatments.
- Conditions
- Parkinson's Disease, Essential Tremor, Dystonia
- Trial name
- NCT01581580
- Testing
- Medtronic Activa Tremor Control System, Deep Brain Stimulation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Learning Disorders, Specific, Learning Disabilities
Examining the Effect of a Digital Medical Device for Cognitive and Musical Training in Children With Reading Disabilities
The goal of this clinical trial is to assess the effect on reading skills of the digital medical device Poppins Clinical for cognitive and musical training in pediatric participants (ages 7-11) with a specific learning disability…
- Conditions
- Learning Disorders, Specific, Learning Disabilities, Specific Learning Disorder, With Impairment in Reading, Dyslexia
- Trial name
- POPPINS-CE (NCT06596980)
- Testing
- Poppins Clinical
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Poppins
Chronic Insomnia, Sleepiness
Sleep Time and Insomnia Factors Among Professional Flight Members
Sleep is a physiological function that plays an essential role in many somatic, cognitive or psychological processes. Although the criteria for sleep effectiveness are multiple, its quantity is unanimously recognized as a major…
- Trial name
- SOMNAVI (NCT04761796)
- Testing
- Sleeping condition self-questionnaire
- Where
- France
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Mild Hypoxic Ischemic Encephalopathy of Newborn
Cool Prime Comparative Effectiveness Study for Mild HIE
To determine effectiveness of therapy to improve neurodevelopmental outcomes in infants with mild HIE. To determine the adverse effects of Therapeutic Hypothermia (TH) in mild HIE on the neonate and his/her family.
- Trial name
- COOLPRIME (NCT04621279)
- Testing
- Normothermia, Whole body therapeutic hypothermia
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- University of Texas Southwestern Medical Center
Piriformis Syndrome, Extracorporeal Shock Wave Therapy
Piriformis Syndrome; Extracorporeal Shock Wave Therapy and Dry Needling
This study is being conducted on patients with piriformis syndrome. Patients are divided into two groups by list randomization method: Extracorporeal shock wave therapy (ESWT) group and Dry neddling (DN) group.
- Trial name
- NCT06530862
- Testing
- ESWT+stretching exercises, Dry needling+stretching exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul Training and Research Hospital
Low Back Pain, Postural
Functional Pathologies of the Musculoskeletal System in Physiotherapy Students
This study map the occurrence of functional pathologies of the musculoskeletal system in students of the bachelor's program of physiotherapy of the Third Faculty of Medicine, Charles University, and aim on improvement of them.
- Trial name
- FUNPAMUS (NCT05544188)
- Testing
- Differential diagnostic
- Where
- Czechia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Chronic Pain, Neck Pain
Sensorimotor Exercises Practice and Yoga in Chronic Neck Pain
Neck pain is an important public health problem with a high lifetime prevalence and frequently occurring in all industrialized countries. Clinical practice guidelines for chronic neck pain recommend conservative management.
- Trial name
- NCT05496127
- Testing
- Sensorimotor Exercises and Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medipol University
Healthcare Access, Experience
Learning Differences in Medical Education
A learning difference or disability is a reduction in intellectual ability (GMC, 2024). It causes lifelong difficulty with everyday activities. Different individuals require different levels of support.
- Conditions
- Healthcare Access, Experience, Learning Disabilities
- Trial name
- NCT07585708
- Testing
- Experience of healthcare
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Nottingham
Alzheimer Disease(AD), Sarcopenia
Silkworm Pupa Powder Improves Dementia.
The purpose of this clinical trial is to determine whether silkworm pupa powder is effective in treating Alzheimer's disease. It will also investigate whether silkworm pupa powder can improve the nutritional and frailty status of…
- Conditions
- Alzheimer Disease(AD), Sarcopenia, Asthenia
- Trial name
- NCT06898476
- Testing
- Silkworm pupa powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Coronary Artery Diseases, Myocardial Infarction
The Efficacy of Influenza Vaccination in Patients With Coronary Artery Diseases
This study wishes to understand: 1. whether vaccination against influenza in coronary artery disease (myocardial infarction and stable angina) patients is as effective as it is in healthy subjects; 2.
- Conditions
- Coronary Artery Diseases, Myocardial Infarction, Stable Angina
- Trial name
- NCT00607217
- Testing
- influenza vaccine
- Where
- Iran
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
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