Clinical trials: Neurologic Symptoms
Adult Women
Interoceptive Awareness and Dream Themes
Individual differences in reported dream themes may reflect not only waking emotional and cognitive experiences but also characteristic ways of attending to, interpreting, and regulating bodily signals.
- Trial name
- NCT07716514
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Hypotension, Consciousness, Level Altered
The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients
Unexpected deaths and unplanned intensive care unit (ICU) admissions are common during hospital stay and are often preceded by warning abnormalities in patients' vital signs.
- Conditions
- Hypotension, Consciousness, Level Altered, Airway Disease, Respiratory Failure
- Trial name
- SPHERE (NCT06503016)
- Testing
- Phosphocreatine
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Università Vita-Salute San Raffaele
Post Traumatic Stress Disorder
Characterization of Olfactory Perception in Post-Traumatic Stress Disorder
The core symptoms of post-traumatic stress disorder (PTSD) include flash backs, intrusive pictures and thoughts related to the traumatic event, hyperalertness, avoidance of traumatic relevant environmental triggers and emotional…
- Trial name
- TRAUMODO (NCT06494306)
- Testing
- European Test of Olfactory Capabilities (ETOC), Standardized Hedonicity Test, Questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Migraine
Migraine Induction Properties of PACAP-38 After Eptinezumab in Migraine Without Aura Patients.
To investigate whether administration of calcitonin gene-related peptide (CGRP) binding monoclonal antibodies eptinezumab prevents pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) induced migraine attacks in…
- Trial name
- NCT05635604
- Testing
- Eptinezumab, PACAP-38
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- Danish Headache Center
Bladder, Overactive, Parkinson Disease
Effect of Medical Cannabis for Non-motor Symptoms of Parkinson's Disease
Medical cannabis (MC) is a standard treatment in Israel to Parkinson's disease (PD) patients suffering from pain. Nevertheless, it is not known about MC effectiveness for other non-motor symptoms of the disease.
- Trial name
- NCT05106504
- Testing
- Medical Cannabis
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Pain, Acute Postoperative
Erector Spinae Plane Block Versus Thoracic Paravertebral Block in Laparoscopic Cholecystectomy
The study is planned as a single-center prospective randomized study and includes patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07149584
- Testing
- ESPB, TPVB, IV
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Glioblastoma
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer.
- Trial name
- Key LARGO (NCT06625684)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Intracerebral Hemorrhage
Treatment of Intracerebral Hemorrhage in Patients on Non-vitamin K Antagonist
Novel, non-vitamin K antagonist oral anticoagulants (NOAC) target selected players in the coagulation cascade as the direct thrombin inhibitor dabigatran and the factor Xa-inhibitors apixaban and rivaroxaban.
- Trial name
- TICH-NOAC (NCT02866838)
- Testing
- Tranexamic acid, Saline 0.9%
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- University Hospital, Basel, Switzerland
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Acute Pain
Pharmacokinetics and Safety of MNK-155 in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain
An open-label study of the pharmacokinetics (PK) and safety of MNK-155 in postsurgical adolescent subjects aged 12 to 17 years with moderate to severe acute pain.
- Trial name
- NCT02767349
- Testing
- MNK-155
- Where
- United States
- Sponsor
- Mallinckrodt
Depressive Episode, Posttraumatic Stress Disorder
Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation
The purpose of this study is to determine whether transcranial magnetic stimulation (TMS) is effective in the treatment of suicidal thinking in individuals with a depressive episode and either posttraumatic stress disorder…
- Conditions
- Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
- Trial name
- NCT01212848
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Longitudinal Profiling of Plasma-Derived Glial Extracellular Vesicles in Alzheimer's Disease
This project aims to longitudinally profile plasma-derived GDEVs and plasma biomarkers of neuroinflammation across three stages of the AD continuum (Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's…
- Conditions
- Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, Alzheimer's Disease Dementia, Alzheimer's Disease (AD)
- Trial name
- GLEVAD (NCT07803055)
- Testing
- blood sampling
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pain
Subcutaneous Botulinum Toxin for Cutaneous Allodynia - Enriched Responder Trial
Superficial injection of Botulinum toxin has been advocated for cosmetic purposes but has also been reported to be helpful for some pain conditions.
- Trial name
- NCT00822926
- Testing
- Botulinum Toxin Type A, Saline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Pain
Reversal of Ketamine Pharmacodynamic Effects With Naloxone
The purpose of this study is to determine whether the analgetic and other effects effect of ketamine are partly mediated through opioid receptors
- Trial name
- NCT00921765
- Testing
- Saline, Saline + Ketamine, Naloxone + Ketamine
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Ullevaal University Hospital
Blindness
Enhanced Tactile Memory in the Blind
This study will determine if the brain regions in blind people that would normally be involved in vision are used instead to remember touch.
- Trial name
- NCT00076700
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Shoulder Instability
Effectiveness of a Standardised Stabilisation Exercise Protocol in Volleyball Players With Non-traumatic Shoulder Instability
This randomized controlled clinical trial aims to evaluate the effectiveness of a standardized shoulder stabilization exercise program in amateur volleyball players diagnosed with atraumatic shoulder instability.
- Trial name
- NCT07400900
- Testing
- Exercise
- Volunteers
- 22 people
- Sponsor
- Universidad Francisco de Vitoria
Occupational Health, Sleep
Using Cognitive-Behavioral Change and Mobile Technology to Improve RN Sleep and Fatigue
The U.S. registered nurse (RN) workforce is the largest in the Healthcare and Social Assistance Sector and is at high risk for injuries and errors due to poor sleep and fatigue.
- Conditions
- Occupational Health, Sleep, Fatigue, Nurse
- Trial name
- RN-SLEEP (NCT06105307)
- Testing
- RN-SLEEP, Healthy Habit - Educational Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University
Dream Disorder, Thrombotic Infarction
Biological Function of Dreaming in Dreaming and Non-Dreaming Patients With PCA Infarction
This study is a quasi-experimental between-group design. Using a prospective two-arm controlled exploratory study, data will be collected on an initial assessment of the effects of a specific neurological sample after thrombotic…
- Conditions
- Dream Disorder, Thrombotic Infarction, PCA Infarct
- Trial name
- BFD (NCT04749992)
- Testing
- Polysomnographic examination in sleep laboratory (PSG measurement)
- Where
- 2 sites in Germany
- Volunteers
- 142 people
- Sponsor
- International Psychoanalytic University Berlin
Neck Pain
Effect of Neck Strength Training on Health-related Quality of Life in Females With Neck Pain
The purpose of this study is to determine whether intensive one-year neck strength training can enhance health related quality of life in females with chronic neck pain.
- Trial name
- NCT01057836
- Testing
- Neck endurance training, Stretching
- Where
- Finland
- Volunteers
- 180 people
- Sponsor
- Jyväskylä Central Hospital
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