Clinical trials: Neurologic Symptoms
Tooth, Impacted, Trismus
Dexketoprofen Dosage According to Chronotherapy
Lower third molar extraction is one of the most common treatments in oral surgery practice. It is a treatment with inherent complications such as postoperative pain, swelling or trismus.
- Conditions
- Tooth, Impacted, Trismus, Pain, Inflammatory Response
- Trial name
- NCT05176158
- Testing
- Dexketoprofen 25 MG
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Sickle Cell Crisis
Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults.
The analgesic treatment for vaso-occlusive crisis (VOC) in sickle-cell patients is an emergency. The reference treatment is morphine, which requires a venous way sometimes difficult to obtain in these patients.
- Trial name
- DREPSUFINDOL (NCT04076748)
- Testing
- Sufentanil, EMONO
- Where
- 8 sites in France, French Guiana and 1 more
- Volunteers
- 115 people
- Sponsor
- University Hospital, Bordeaux
Low Back Pain, Mechanical
Comparative Study of Static and Dynamic Back Supports for Lower Back Pain
Lower back pain is one of the most common conditions affecting humans. Lower back supports are a common device used in order to alleviate the pain.
- Trial name
- NCT01269619
- Testing
- Dynamic back support, Static back support
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Wolfson Medical Center
Medication Management
Improving Caregiver Mediated Medication Management- The 3M Study
This study sought to improve medication management by caregivers of community dwelling patients with dementia or simple memory loss.
- Trial name
- NCT03127930
- Testing
- Intervention
- Volunteers
- 183 people
- Sponsor
- University of Pittsburgh
Dysarthria as Late Effect of Stroke
Efficacy of a Digital Therapeutic for People With Dysarthria After Stroke
This pilot trial will establish the feasibility of a new digitized speech rehabilitation developed for patients with post-stroke dysarthria.
- Trial name
- NCT05146765
- Testing
- Mobile application, Treatment as usual
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ewha Womans University Seoul Hospital
Chronic Low Back Pain
Aging Back Clinics
The purpose of this study is to compare two different ways to treat chronic low back pain. The two types of treatment that the investigators will compare are called Usual Care and ABC Care. Usual Care tends to focus on the spine.
- Trial name
- NCT03564600
- Testing
- Aging Back Clinics management
- Where
- 3 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sarcopenia
Sarcopenia Physical Activity and Metabolomic
Muscle failure (sarcopenia or dynapenia) is a factor of frailty and therefore, ultimately, of loss of autonomy in the elderly. Currently, no biomarker of muscle failure has a high sensitivity, specificity and positive predictive…
- Trial name
- SPAM (NCT05199207)
- Testing
- Physical activity programm
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain, Dental Anxiety
Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children
The goal of this clinical study is to learn whether aromatherapy and digital anesthesia are effective in reducing dental anxiety and pain during tooth extraction in children.
- Conditions
- Pain, Dental Anxiety, Tooth Extraction
- Trial name
- NCT07547371
- Testing
- Traditional Local Anesthesia (Conventional Syringe), Aromatherapy (Lavender or Orange Essential Oil), Digital Local Anesthesia (SleeperOne 5)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arzu Pınar Erdem
Developmental Dyslexia
Telerehabilitation vs. in Presence Rehabilitation of Reading Disorders Using the Rhythmic Reading Training (RRT)
The aim of the study is to compare the effectiveness of telerehabilitation vs. in presence rehabilitation of reading disorders, using a rhythm-based intervention for reading (i.e., Rhythmic Reading Training)
- Trial name
- NCT04995471
- Testing
- In presence RRT - prototype software, In presence RRT - online platform, Tele-RRT - prototype software
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Neck Pain
Effect of Bruegger's Exercise in Chronic Mechanical Neck Pain With Forward Head Posture
The purpose of the study is to investigate the effect of adding Bruegger's exercises on conventional exercise program in treatment of forward head posture.
- Trial name
- NCT07669844
- Testing
- Core stability exercise, Bruegger's training
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Neurogenic Bladder, Neurogenic Bowel
Sacral Neuromodulation in Neurogenic Patients
The goal of this observational study is to evaluate efficacy and safety of sacral neuromodulation in neurogenic patients compared to non-neurogenic (idiopathic) patients. [.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Urge Incontinence, Overactive Bladder
- Trial name
- NCT05688644
- Testing
- InterStim II
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Omri Schwarztuch Gildor
Intrathecal Dexmedetomidine, Adductor Canal Block
Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty
The aim of this work is to evaluate the effect of combined intrathecal dexmedetomidine and adductor canal block for analgesia after total knee arthroplasty (TKA).
- Conditions
- Intrathecal Dexmedetomidine, Adductor Canal Block, Analgesia, Total Knee Arthroplasty
- Trial name
- NCT06837844
- Testing
- Intrathecal Dexmedetomidine, Adductor Canal Block, Intrathecal Dexmedetomidine + Adductor Canal Block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Kafrelsheikh University
Liver Health, Digestive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Symptoms Associated With Liver and Digestive Health
This study will evaluate the effects of Edenboost Alpha Cleanse, a dietary supplement, on symptoms associated with liver and digestive health.
- Conditions
- Liver Health, Digestive Health, Fatigue, Abdominal Bloating
- Trial name
- NCT07738744
- Testing
- Edenboost Alpha Cleanse
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Edenboost
Diabetes, High Blood Pressure
Study Title: Food Rx
Researchers are trying to determine if subjects with lack of access to healthy food and a long term health problem, are helped by a weekly box of healthy groceries and nutrition education.
- Conditions
- Diabetes, High Blood Pressure, Obesity, Hypertension
- Trial name
- NCT03937934
- Testing
- Nutrition Education
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Parkinson Disease, Dystonia
Physiological Brain Atlas Development
Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.
- Conditions
- Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder
- Trial name
- NCT01210534
- Testing
- No intervention
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Ohio State University
Pain
Mechanism-based Choice of Therapy for Neuropathic Pain
Mechanism-based choice of therapy for neuropathic pain: Can treatments success in neuropathic post-operative pain be coupled to psychophysical pain modulation profile?
- Trial name
- NCT01359514
- Testing
- Pregabalin, Duloxetine
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Rambam Health Care Campus
Restlessness
Loxapine in the Management of Restlessness During Mechanical Ventilation Weaning
This study aims to assess the efficacy of a drug (loxapine, a neuroleptic) in calming patients down in a situation of restlessness during mechanical ventilation weaning.
- Trial name
- Sevralox (NCT01193816)
- Testing
- loxapine
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Limbic Encephalitis With LGI1 Antibodies
Antibody-mediated LGI1 Encephalitis: Symptoms, Biomarkers, and Mechanisms of the Chronic Phase of the Disease
The encephalitis mediated by antibodies against Leucine-rich, glioma inactivated 1 protein (anti-LGI1 encephalitis) predominantly affects men (M:F, 6:4) and mostly older than 60 years.
- Trial name
- NCT06515106
- Testing
- Remote cognitive rehabilitation program
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Pain, Post Operative Pain
Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery
To evaluate the safety and efficacy of self-titration to effective analgesia with inhaled AeroLEF in patients with moderate/severe acute pain in the post-surgical setting.
- Trial name
- Pain (NCT00791804)
- Testing
- AeroLEF
- Where
- 2 sites in Canada
- Volunteers
- 19 people
- Sponsor
- YM BioSciences
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