Clinical trials: Neurological; Disorder, Nervous System
Abdominal Pain
Effect of tDCS on Chronic Abdominal Visceral Pain in HCC Patients
To evaluate the effect of transcranial direct current stimulation (tDCS) applied to the motor cortex to reduce chronic abdominal visceral pain in a group of participants with hepatocellular carcinoma
- Trial name
- NCT02928237
- Testing
- transcranial direct current stimulation tDCS
- Volunteers
- 40 people
- Sponsor
- Assiut University
Stammering
Effects of Tele Speech Therapy on the Treatment of Stammering in Adults Who Stutter
The aim of the study is to determine the effectiveness of telespeech therapy on the treatment of stammering.
- Trial name
- NCT06937437
- Testing
- Teletherapy, Traditionally speech therapy
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Acute Ischemic Cerebrovascular Disease, Post Stroke Aphasia
EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION ON NAMING IN APHASIC PATIENTS WITH ACUTE ISCHEMIC STROKE
The use of transcranial direct current stimulation (tDCS) for the management of deficits developed in stroke is a relatively new type of management option.
- Conditions
- Acute Ischemic Cerebrovascular Disease, Post Stroke Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired
- Trial name
- NCT07496645
- Testing
- Transcranial Direct Current Stimulation
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
Neuropathy, Paraneoplastic
MC-5A for Chemotherapy Induced Peripheral Neuropathy
Painful chemotherapy induced peripheral neuropathy (CIPN) is a common complication of cancer therapy with few treatment options.
- Trial name
- NCT01261780
- Testing
- MC-5A
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Wisconsin, Madison
Postoperative Pain
Percutaneous Peristyloid Glossopharyngeal Block After Tonsillectomy
Adenotonsillectomy surgery in paediatrics is commonly managed as an ambulatory surgery. This may be attributed to the use of the electro-dissection surgical technique that decreases the incidence of immediate postoperative…
- Trial name
- NCT04970680
- Testing
- glossopharyngeal nerve block
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Analgesia, Epidural, Urodynamics
Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study
Postoperative urinary retention (POUR) is one of the most common complications after surgery and neuraxial anesthesia of which the treatment of choice is bladder catheterization 1.
- Conditions
- Analgesia, Epidural, Urodynamics, Urinary Retention
- Trial name
- NCT01220362
- Testing
- Bupivacain 0.125%, Bupivacain 0.125%/Fentanyl 2mcg/ml
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Peripheral Neuropathy, Complex Regional Pain Syndromes (CRPS)
Efficacy of Transdermal Fentanyl for Chronic Neuropathic Pain
The efficacy of fentanyl TTS for the treatment of neuropathic pain remains to be established, although opioids in general are clearly effective for neuropathic pain and fentanyl TTS has been shown to be effective for treating…
- Trial name
- NCT00181246
- Testing
- Transdermal Fentanyl
- Volunteers
- 53 people
- Sponsor
- Johns Hopkins University
Tension-Type Headache, Cervicogenic Headache
The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.
This project comprises two studies; a cross-sectional study and a randomized controlled trial. 1. The goal of the cross-sectional study is to compare multiple outcome parameters in different headache types: tension type (TTH)…
- Conditions
- Tension-Type Headache, Cervicogenic Headache, Myofascial Headache
- Trial name
- COMPHAS_RCT (NCT06100588)
- Testing
- Dry Needling, Manual therapy
- Where
- Belgium
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University Ghent
Pain, Neuropathic, Neuropathic Pain
Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects
This study is being conducted to assess the effects of GSK1014802 and a positive control, lidocaine, on tests of peripheral nerve excitability. This will be a double blind, placebo controlled, 4-period cross over study.
- Trial name
- NCT00964288
- Testing
- GSK1014802 low dose, Lidocaine, GSK1014802 high dose
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Biogen
Diplegic Cerebral Palsy
"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy
" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy.
- Trial name
- NCT06343688
- Testing
- "Assessment of Balance and Lower Extremity Gross Motor Function with and without DAFO"
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Ocular Motility Disorder
Evaluation and Treatment of Pediatric Eye Diseases
This study offers evaluation and treatment for patients with pediatric eye diseases, particularly amblyopia and strabismus. The protocol is not designed to test new treatments; rather, patients will receive current standard of…
- Trial name
- NCT00006422
- Testing
- current standard of care treatments
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Eye Institute (NEI)
Pain, Acute Post-Operative, Dexmedetomidine
Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological Surgery
The aim of this study is to investigate and compare the effects of a continuous infusion of low-dose esmolol and dexmedetomidine versus placebo on intraoperative and postoperative opioid consumption and analgesic efficacy in…
- Conditions
- Pain, Acute Post-Operative, Dexmedetomidine, Analgesia, Esmolol
- Trial name
- NCT07846722
- Testing
- Esmolol hydrochloride, Dexmedetomidine, Normal (0.9%) saline
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Vasiliki Samartzi
Post Operative Delirium
The Effect of Preoperative Duloxetine on the Occurance of Postoperative Delirium in Patients Undergoing Cancer Surgery.
This is prospective double-blinded placebo-randomized controlled trial that aims to compare the effect of preoperative administration of oral duloxetine 60 mg on decreasing the incidence of postoperative delirium in cancer…
- Trial name
- NCT05949229
- Testing
- Duloxetine 60 MG
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Amira Hassan Ahmed Ali
Pain, Neuropathic Pain
Nerveblocks for Persistent Pain After Breast Cancer Surgery
Persistent pain after breast cancer surgery (PPBCS) affects 25-60% of breast cancer survivors and nerve damage has been implicated as the cause of this neuropathic pain condition.
- Conditions
- Pain, Neuropathic Pain, Breast Cancer
- Trial name
- NCT02336529
- Testing
- Bupivacaine, NaCl
- Volunteers
- 48 people
- Sponsor
- Kenneth Geving Andersen
Sleep Deprivation
Predicting Cognitive Resilience Against Sleep Loss
Resilience is the ability to cope effectively and adapt to a wide range of stressful environmental challenges. Sleep loss has been shown to reduce activity in the brain regions responsible for resilience.
- Trial name
- NCT01651429
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Tourette Syndrome
FAAH Inhibitor Trial for Adults With Tourette Syndrome
The purpose of this trial is to examine the safety, tolerability and feasibility in the use of a FAAH inhibitor for the treatment of adults with Tourette syndrome.
- Trial name
- NCT02134080
- Testing
- PF-04457845
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Fibromyalgia
Yoga Impact in Fibromyalgia, Primary Health Care
This study aims to evaluate the effectiveness of a complementary therapy using Yoga within the scope of First Health Care in Portugal, in pain control, quality of life and well-being of the patients with Fibromyalgia.
- Trial name
- NCT06646796
- Testing
- Yoga
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- University of Coimbra
Tardive Dyskinesia
Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia
The primary objective of this study is to evaluate the efficacy of NBI-1065890 compared with placebo for the treatment of tardive dyskinesia (TD) in adult participants.
- Trial name
- NCT07365462
- Testing
- NBI-1065890
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurocrine Biosciences
Lumbosacral Radiculopathy, Sciatica
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
The Move-MORE study is designed to evaluate a multicomponent mindfulness and movement program for patients with lumbosacral radiculopathy.
- Conditions
- Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar
- Trial name
- Move-MORE (NCT07125027)
- Testing
- Move-MORE
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National University of Natural Medicine
Epileptic Seizure
A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI
1. By following up the prognosis of surgical patients, the application value of Cortex ID quantitative analysis in the localization of epilepsy foci was studied. 2.
- Trial name
- NCT05567042
- Testing
- No intervention
- Volunteers
- 50 people
- Sponsor
- Li Shuangshuang
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