Clinical trials: Neurological; Disorder, Nervous System
Sleep Disorders
Efficacy and Safety Assessment of ZOlpidem (Stilnox CR) in Patients With Chronic insomNIA
Primary Objective: To evaluate the efficacy and safety of the use of Stilnox CR in Mexican patients with chronic insomnia at the prescription conditions of daily practice Secondary Objective: To evaluate the satisfaction of the…
- Trial name
- NCT01024192
- Testing
- ZOLPIDEM SL800750
- Where
- Mexico
- Volunteers
- 135 people
- Sponsor
- Sanofi
Fall Patients, Delirium
Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
This project will implement a 2 step protocol for multidisciplinary geriatric assessment in the Emergency Department (ED). Candidate: Dr.
- Conditions
- Fall Patients, Delirium, Quality of Life, Functional Status
- Trial name
- IMAGE (NCT04068311)
- Testing
- Geriatric Screening tools
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Ohio State University
Myocardial Infarction, Angina Pectoris
Improving Intermediate Risk Management. MARK Study
Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes difficult.
- Conditions
- Myocardial Infarction, Angina Pectoris, Stroke, Peripheral Arterial Disease
- Trial name
- MARK (NCT01428934)
- Where
- Spain
- Volunteers
- 2,495 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Neuropathic Pain, Spinal Cord Injury
Ultramicronized PEA (Normast) in Spinal Cord Injury Neuropathic Pain
Randomized, double-blinded, placebo-controlled, parallel group study of ultramicronized PEA (Normast)600 mg x 2 daily or corresponding placebo with a week of baseline period followed by 1 x 12 weeks treatment period.
- Trial name
- NCT01851499
- Testing
- Ultramicronized PEA (Normast)
- Where
- 2 sites in Denmark
- Volunteers
- 73 people
- Sponsor
- Danish Pain Research Center
Postoperative Delirium, Sedation
The Effect of Reversal of Remimazolam Sedation With Flumazenil on Cognitive Function in Patients Undergoing Hip Arthroplasty Under Spinal Anesthesia
This clinical trial aims to establish whether reversing remimazolam sedation with flumazenil can prevent postoperative neurocognitive disorders in patients undergoing total hip replacement surgery.
- Conditions
- Postoperative Delirium, Sedation, Remimazolam, Hip Arthroplasty, Total
- Trial name
- NCT07277881
- Testing
- remimazolam sedation reversal with flumazenil
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Spinocerebellar Degeneration
An Extension Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)
The purpose of this study is to evaluate the long-term safety, efficacy, and pharmacokinetics of KPS-0373 in SCD patients.
- Trial name
- NCT01970111
- Testing
- KPS-0373, High dose, KPS-0373, Low dose
- Where
- Japan
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Stroke, Acute, Gait, Spastic
Rhythmic Auditory Stimulation as Pre-Gait Training for Improving Balance and Weight Shifting in Rehabilitation Patients
The purpose of this study is to explore whether Rhythmic Auditory Stimulation (RAS) as pre-gait training can help improve balance, weight-shifting abilities, and overall gait performance in stroke patients undergoing…
- Conditions
- Stroke, Acute, Gait, Spastic, Attention Impaired
- Trial name
- NCT06995092
- Testing
- Music therapy, Standard physiotherapy program
- Where
- Malaysia
- Volunteers
- 27 people
- Sponsor
- University of Malaya
Ischemic Stroke, Delirium
DEliriuM in STroke: the Link Between Stroke, Delirium and Long-term Cognitive Impairment
Primary objective of this study: determine whether PSD is a risk factor for PSCI, independent of brain frailty and premorbid cognitive functioning. Secondary objectives: 1.
- Conditions
- Ischemic Stroke, Delirium, Cognitive Impairment
- Trial name
- DE-MIST (NCT06650436)
- Testing
- EEG, MRI, Depression screening and neuropsychological tests
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Brain Injuries
Validating the MATADOC Against Best Practice Standard External Reference Standard
The purpose of this project is to further develop a standardized music-based measure used in music therapy with adults who have emerged from coma following profound brain injury, but are not able to demonstrate responsiveness to…
- Trial name
- MATADOC (NCT02959736)
- Testing
- MATADOC and CRS-R
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Temple University
Cerebral Palsy
Lower Extremity Functional Training (LIFT) on Gross Motor Function and Gait in Children With Spastic CP
Cerebral Palsy is a developmental disorder caused by damage to the brain before, during or after birth. Spastic Cerebral Palsy is one of the most common types of cerebral Palsy. It affects about 80% of cerebral palsy.
- Trial name
- LIFT (NCT05460936)
- Testing
- Lower Extremity Functional Training, conventional physical therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Cystic Fibrosis, Bone Loss
CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis
Study is looking at the effects of cystic fibrosis treatment on bone muscle.
- Conditions
- Cystic Fibrosis, Bone Loss, Muscle Loss
- Trial name
- NCT04206436
- Testing
- Cftr Modulators
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Indiana University
Epilepsy
Progesterone vs Placebo Therapy for Women With Epilepsy
The purpose of this investigation was to determine if cyclic adjunctive progesterone supplement is superior to placebo in the treatment of intractable seizures in women with and without catamenial epilepsy.
- Trial name
- NCT00029536
- Testing
- Progesterone Lozenges
- Where
- 15 sites in United States, Canada
- Volunteers
- 294 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hearing Impairment
Speech-Evoked Auditory Potentials: Multisite Pediatric Evaluation
The goal of this study is to evaluate the sensitivity of a newly-developed prototype device in its ability to measure brain responses to speech sounds in an infant population.
- Trial name
- SEFR (NCT07392164)
- Testing
- A newly developed prototype device for speech-evoked EFR Measurement
- Where
- 3 sites in Australia, Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Susan Scollie
Muscular Dystrophies, Scapular Dyskinesis
Evaluation of a Textile Scapula Orthosis
Shoulder instability due to muscle weakness is a common problem in disorders of the upper extremities. During arm motion, the scapula acts as a dynamic base for the humeral head.
- Conditions
- Muscular Dystrophies, Scapular Dyskinesis, Muscular Dystrophy, Facioscapulohumeral, Muscle Weakness
- Trial name
- ScapOrthosis (NCT04154098)
- Testing
- Scapula orthosis assistance, Manual scapula assistance, No assistance
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 8 people
- Sponsor
- Swiss Federal Institute of Technology
Peripheral Vertigo
Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo.
Background: Vertigo as acute symptom seem to be one of most common presentation in ED, can be treated in ED with multiple medication .
- Trial name
- BBPVOMSBAFH (NCT05586763)
- Testing
- Metoclopramid ( 10mg), IM promethazine (25mg) , IM prochloroperazine( 12.5mg)
- Where
- Oman
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Spinal Cord Injury, Paraplegia
Exoskeletal-assisted Walking to Improve Mobility, Bowel Function and Cardio-Metabolic Profiles in Persons With SCI
The primary objective of this study is to achieve successful walking skills using exoskeletal walking devices over the course of 36 sessions in 3 months at specific velocities and distances in people with chronic SCI who are…
- Conditions
- Spinal Cord Injury, Paraplegia, Tetraplegia
- Trial name
- EAWSCI (NCT02314221)
- Testing
- Exoskeletal-assisted walking (ReWalk, Ekso)
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Sarcopenia
Could a Preoperative Feeding Jejunostomy Decrease Sarcopenia for Patients With Oesogastric Adenocarcinoma ?
The study of sarcopenia is a subject that is the subject of numerous research and publications, particularly because of its link with a poor prognosis for many cancers.
- Trial name
- NCT03574116
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiovascular Diseases, Acute Abdomen
Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood
This study aimed to evaluate the correlation between the point of care blood analysis obtained from skin puncture blood and conventional blood analysis obtained from venous and arterial blood.
- Conditions
- Cardiovascular Diseases, Acute Abdomen, Respiratory Disease, Renal Disease
- Trial name
- NCT03096665
- Testing
- blood test
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Hanyang University
Multiple Sclerosis, Relapsing-Remitting
Identifying Immune Biomarkers of Disease and Disease Control in Autoimmune Neurological Disease Using Autologous Haematopoietic Stem Cell Transplantation
The underlying disease mechanisms which occur in patients with immune mediation neurological diseases, such as Multiple Sclerosis (MS), are incompletely understood.
- Trial name
- BIO-MS (NCT06195800)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Sarcopenia, Cirrhosis of the Liver
Oral Branched-chain Amino Acid Supplementation for Cirrhotic Patients With Sarcopenia
The goal of this clinical trial is to compare the nutritional parameters after 24-week supplementation of branched-chain amino acids in cirrhotic patients with low muscle mass.
- Trial name
- BCAASarcopenia (NCT06121492)
- Testing
- Branched-chain amino acid
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
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