Clinical trials: Neurological; Disorder, Nervous System
Parkinson Disease
Dopaminergic restauratIon by intraVEntriculaire Administration
Prospective monocentric randomized controlled open-label proof-of-concept study in cross-over of two 1-month periods and a long-term follow-up period not to exceed September 30, 2023, with 2 groups: Intracerebroventricular…
- Trial name
- DIVE (NCT04332276)
- Testing
- A-dopamine, optimized oral treatment
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Lille
Neurogenic Bladder
Bilateral Comparison of Unilateral Sacral Neuromodulation Test Stimulation in the Treatment of Neurogenic Bladder
Neurogenic bladder (NB) is a general term for a series of lower urinary tract symptoms and complications caused by bladder and/or urethral dysfunction caused by nervous system lesions.
- Trial name
- NCT07505940
- Testing
- bilateral sacral nerve stimulation (BNS)
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Qilu Hospital of Shandong University
Spinal Cord Injuries, Neurological Injury
Physiological Changes Induced Through MEP Conditioning in People With SCI
The study team is currently recruiting volunteers who are interested in participating in a brain-spinal cord-muscle response training study that aims to better understand the changes that take place in the nervous system as a…
- Conditions
- Spinal Cord Injuries, Neurological Injury, Paralysis, Spasticity, Muscle
- Trial name
- NCT04286191
- Testing
- Operant Conditioning, Control Group
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Dementia, Agitation
Person- Centred Care Among Nursing Home Patients With Dementia
Dementia is a common and devastating disease in the elderly. No cure exist and there is an increasing need for care. To improve knowledge on how to provide better care for the patients with dementia in nursing homes, the…
- Trial name
- NCT01280890
- Testing
- Staff training using VIPS, Staff training using DCM, Control group
- Volunteers
- 624 people
- Sponsor
- Norwegian Centre for Ageing and Health
Stroke, Hemiparesis
Motor Imagery Added to Robot-Assisted Hand Rehabilitation After Stroke
Loss of upper extremity and particularly hand function after stroke reduces independence in daily activities such as eating, dressing, and personal care.
- Conditions
- Stroke, Hemiparesis, Activities of Daily Living
- Trial name
- NCT07760090
- Testing
- Robot-assisted hand rehabilitation, Motor imagery training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Spastic Hemiplegia
Biomechanical Muscle Properties and Balance in Children With Spastic Hemiplegia
this study will be conducted to investigate the relationship between muscle tone and dynamic stiffness during balance control and postural stability in children with spastic hemiplegia
- Trial name
- BMPB-HCP (NCT07538297)
- Testing
- hemiplegic group, normal group
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Valley University
Visual Impairment
Measuring of Neuro-visual Functionality With Ocusweep
The aim of this study is to measure visual acuity, contrast sensitivity and visual field by SAP-method using a novel device Ocusweep compared to currently widely used methods.
- Trial name
- NCT02258113
- Testing
- Ocusweep, Ocusweep OcuRT
- Where
- Finland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ocuspecto Oy
Cognitive Impairment, Dementia
The Philippine Neurological Association One Database -Dementia
This is a pragmatic, multi-center, prospective, observational, non-interventional study and standing database of patients seen at the training institution for cognitive impairment diagnosed with Mild Cognitive Impairment (MCI) or…
- Conditions
- Cognitive Impairment, Dementia, Mild Cognitive Impairment
- Trial name
- PNA1DB-Dem (NCT05484960)
- Testing
- cognitive assessment
- Where
- 11 sites in Philippines
- Volunteers
- 73 people
- Sponsor
- Philippine Neurological Association
Spasticity, Multiple Sclerosis
Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.
The purpose of this study is to determine the effective dose range and to demonstrate a non-effective dose range of Sativex compared with placebo in relieving symptoms of spasticity due to multiple sclerosis.
- Trial name
- NCT01868048
- Testing
- Sativex
- Sponsor
- GW Research Ltd
Vestibular Diseases, Vestibular Vertigo
Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients
The purpose of this study: To investigate the effectiveness of non-invasive vagus nerve stimulation and vestibular rehabilitation applications in patients diagnosed with Unilateral Vestibular Hypofunction (UVH).
- Conditions
- Vestibular Diseases, Vestibular Vertigo, Vertigo
- Trial name
- NCT06332326
- Testing
- non-invasive vagus nerve stimulation, vestibular rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Postoperative Cognitive Complications, Delirium
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
This is a prospective observational cohort study of adult patients undergoing high-risk surgery at UT Southwestern Medical Center.
- Conditions
- Postoperative Cognitive Complications, Delirium, Perioperative/Postoperative Complications, Brain Injuries
- Trial name
- NCT07577726
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Psychomotor Agitation, Acute Disease
IMPACT: A Study to Explore the Efficacy and Safety of Paliperidone ER in Patients With Acute Agitation
This study will investigate the effect of paliperidone ER (in combination with or without benzodiazepines) in patients presenting with symptoms of agitation and/or aggression in the context of psychosis, and will generate data…
- Trial name
- NCT01050478
- Testing
- Paliperidone ER, Benzodiazepine
- Where
- 14 sites in Belgium
- Volunteers
- 56 people
- Sponsor
- Janssen Cilag N.V./S.A.
Neuropathic Pain, Spinal Cord Injury
Reliability and Validity of the Turkish Version of the SCIPI
Pain after spinal cord injury (SCI) is common, with the majority of individuals experiencing chronic pain and a significant portion reporting severe pain that interferes with their daily lives.
- Trial name
- NCT06990243
- Testing
- Evaluation Group
- Volunteers
- 40 people
- Sponsor
- Istinye University
Appendicitis, Pain, Postoperative
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
There is concern that pain prescription after outpatient pediatric surgical procedures is excessive and is in excess of patient need.
- Trial name
- NCT03528343
- Testing
- Non-narcotic pain control
- Where
- United States
- Sponsor
- University of Utah
Bipolar Disorder, Mania
Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder
The objectives of this study are to study the safety, effectiveness, tolerability and dosing regimen of risperidone, and olanzapine, in the treatment of mania in Bipolar Disorder I and Bipolar II Disorder in preschool children…
- Trial name
- NCT00181935
- Testing
- risperidone (Risperdal), olanzapine (Zyprexa)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Epilepsy
Tonicity Monitor For Epilepsy and Hypertonic Disorders
Epilepsy is an episodic disorder which can result in recurrent seizures often associated with hypertonia (muscle stiffening) and myoclonia (involuntary muscle jerking).
- Trial name
- NCT02110589
- Testing
- Epidetect
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vikel Ltd
Cervical Radiculopathy
Mulligan Mobilization & Stretching Effects of Cervical
1. To evaluate the effectiveness of mulligan mobilization and stretching exercises in reducing pain in individuals with cervical radiculopathy. 2.
- Trial name
- NCT07045974
- Testing
- Group A-Mulligan Mobilization, Group B-Stretching Exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Down Syndrome
Video Based Breathing Exercise Rehabilitation
The aim of the study was to investigate the effect of video game-based lung volume increasing training on respiratory mechanics in children with developmental delays.
- Trial name
- NCT06125990
- Testing
- Experimental: Study Group (SGr)
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Saglik Bilimleri Universitesi
Alzheimer's Disease in Down Syndrome
Down Syndrome Clinical Trials - Study of Alzheimer's Disease in Down Syndrome
The primary objective is to characterize trajectories of change on the primary outcome measures in this study population through longitudinal collection of measures of cognition, function, behavior, and health status.
- Trial name
- LIFE-DSR (NCT04149197)
- Where
- 14 sites in United States
- Volunteers
- 252 people
- Sponsor
- LuMind IDSC Foundation
Malnutrition
Malnutrition Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement
Evaluation of malnutrition with the help of the GLIM criteria. Muscle mass measurement, as recommended in the GLIM criteria was done with the help of abdominal CT scan and BIA.
- Trial name
- NCT05174715
- Testing
- BIA
- Volunteers
- 260 people
- Sponsor
- Klinikum St. Georg gGmbH
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