Clinical trials: Neurological Complications
Surgery, Surgery--Complications
Patterns and Outcomes of Neurosurgery in England Over a Five-year Period
Neurosurgical practice has seen many important changes over several decades with advances in treatments and the types of patients treated.
- Conditions
- Surgery, Surgery--Complications, Neurological Morbidity, Neurological Diseases or Conditions
- Trial name
- NCT05097066
- Testing
- Neurosurgical procedure
- Volunteers
- 371,418 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Covid19, Neurological Complication
COVID-19 Infection: Exploration of Respiratory Control Center Abnormalities
The purpose of the present study is to determine whether there is a decrease in the emotional response to experimental induction of dyspnea by hypoxic stimulation in subjects with a "neurological" form of COVID-19, compared to…
- Trial name
- CRC-COVID (NCT04363749)
- Testing
- hypoxia : 14.3 and 12.7% FIO2, hypercapnia 7% CO2, inspiratory mechanical constraint
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurological Morbidity, Surgical Complication
The Implementation of the Classification of Intraoperative Adverse Events (ClassIntra) for Neurosurgical Procedures
In the planned study, the ClassIntra score will be assessed after all neurosurgical procedures in the upcoming 6 months and correlated with all pre- and postoperative data.
- Conditions
- Neurological Morbidity, Surgical Complication, Anesthesia Morbidity
- Trial name
- NCT04956835
- Where
- Germany
- Volunteers
- 750 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Neurological Complication, in Particular TNS or CES
Observational Study on 2-chloroprocaine Hydrochloride 1%
The present study aims to evaluate the relationship between spinal block with 1% solution of 2-chloroprocaine hydrochloride and the onset of all possible neurological adverse events, with particular attention to Transient…
- Trial name
- PASS (NCT02067806)
- Testing
- 2-chloroprocaine hydrochloride, 1%
- Where
- Belgium
- Volunteers
- 394 people
- Sponsor
- Sintetica SA
Anaesthetic Complication Neurological, Central Nervous System Depression
Analysis of Change of Optic Nerve Sheath Diameter in in Patients Operated for Urological Reasons
The assessment of the diameter of the optic nerve sheath (ONSD) using ultrasound can be a very helpful tool in the assessment of increased intracranial pressure in patients operated for urological procedures.
- Trial name
- NCT03485612
- Testing
- Change of Optic Nerve Sheath Diameter
- Where
- Poland
- Volunteers
- 69 people
- Sponsor
- Jagiellonian University
Neurological Injury, Stroke
Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce Neurological Injuries After Surgical Coronary Revascularization (CANON): a Randomised, Controlled, Investigator and Patient Blinded Single Center Superiority Trial With Three Parallel Arms.
The objective of this study is to investigate the value of employing the aortic no-touch off-pump coronary artery bypass technique and the practice of carbon dioxide surgical field flooding for the prevention of type 1 and 2…
- Conditions
- Neurological Injury, Stroke, Postoperative Cognitive Dysfunction, Postoperative Delirium
- Trial name
- CANON (NCT03074604)
- Testing
- aortic no-touch OPCABG, OPCABG with partial clamp applying carbon dioxide, OPCABG with partial clamp
- Where
- Poland
- Volunteers
- 192 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Neurological Complication of Procedure (Disorder)
Novel BIochemical Markers for Predicting Type 2 NEurological Complications of Surgical Coronary Revascularization (BINER)
In this single center prospective cohort study a total of 100 patients scheduled for elective off-pump CABG will be recruited. They will be allocated to one study and one control group according to the presence or absence of…
- Trial name
- BINER (NCT03493256)
- Testing
- exposure to type 2 neurological complications
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Diabetic Nerve Problems, Diabetic Neuropathy
The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic Neuropathy
The study aims to compare the effectiveness and tolerability of using lidocaine 5% patch to 8% capsaicin patch in patients with diabetic neuropathy.
- Conditions
- Diabetic Nerve Problems, Diabetic Neuropathy, Diabetic Complications Neurological
- Trial name
- NCT04238208
- Testing
- Lidocaine 5% patch, Capsaicin 8% Patch, Per 10 Square Centimeters
- Where
- Pakistan
- Volunteers
- 290 people
- Sponsor
- Corporacion Parc Tauli
Diabetes Mellitus, Type 2, Polyneuropathy Diabetes
24-hour Blood Pressure Dynamics and Autonomic Adrenergic Regulation in Type 2 Diabetics
Autonomic neuropathy is a common complication of type 2 diabetes mellitus. Symptoms from cardiovascular autonomic neuropathy include, dizziness, orthostatic hypotension and insufficient heart rate and blood pressure (BP)…
- Conditions
- Diabetes Mellitus, Type 2, Polyneuropathy Diabetes, Autonomic Neuropathy, Diabetic Neuropathies
- Trial name
- NCT04208295
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes, Cardiovascular Disease
A Complex Contraception Registry
The investigators will conduct a prospective observational cohort study to investigate factors that influence contraceptive method utilization among women with medical conditions.
- Conditions
- Diabetes, Cardiovascular Disease, Epilepsy, Migraine
- Trial name
- NCT02219269
- Where
- 5 sites in United States
- Volunteers
- 97 people
- Sponsor
- University of California, San Diego
Neurological Complication
The Influence of Neuromuscular Reversal on Neurological Physical Exam Time in Lumbar Neurosurgical Cases.
Neurological physical exam is a very important outcome that should be evaluated as soon as possible after every lumbar procedures.
- Trial name
- NCT03399890
- Testing
- Neurological physical exam
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Ankara University
Anesthesia; Adverse Effect, Spinal and Epidural, Anaesthetic Complication Neurological
Neurotoxicity of Spinal Anesthesia With Ropivacaine and Bupivacaine
Consenting patients, scheduled for orthopaedic surgery under spinal anesthesia will be randomly assigned (1:1) to receive ropivacaine or bupivacaine as a single shot before the start of surgery, followed by bolus doses of the…
- Trial name
- BuRoNe (NCT03293472)
- Testing
- Ropivacaine, Bupivacaine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Rzeszow
Neurological Complications
Lipids and Neurological Complications in Liver Transplantation
To study the impact of pretreatment of living donor liver transplantation recipients with SMOF lipid on the incidence and severity of post-transplantation neurological complications in patients receiving tacrolimus based…
- Trial name
- LNCLT (NCT02544919)
- Testing
- SMOF lipid (SMOFLIPID) pre treatment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Neurological Complications, Mitral Valve Insufficiency
Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve Surgery
The purpose of this study is to prospectively evaluate major and minor neurologic events in patients undergoing right mini-thoracotomy mitral valve surgery and to compare different aortic clamping techniques; specifically, the…
- Trial name
- NCT02818166
- Testing
- Mitral valve surgery
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Turin, Italy
Coronary Artery Disease, Postoperative Cognitive Dysfunction
Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
It is previously reported that the cerebral oxygen desaturation during cardiac surgery is associated with an increased incidence of cognitive impairment.
- Conditions
- Coronary Artery Disease, Postoperative Cognitive Dysfunction, Neurological Impairment
- Trial name
- NCT00917124
- Testing
- INVOS
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University of Zagreb
HIV, AIDS
NOW Thai HAART Study
After Initiation of HAART in peoples who living with HIV/AIDS in Thailand by the year 2000, rapidly expanded HAART access of national project has been promoted in 2004. Free ARVs (For CD4<200cell/cu.mm.
- Conditions
- HIV, AIDS, Neurological Complications
- Trial name
- NCT00367731
- Testing
- Highly Active Antiretroviral Treatment (combination of :NRTI, NNRTI,or PI)
- Where
- 3 sites in Thailand
- Volunteers
- 500 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand