Clinical trials: Neurological Condition
Postoperative Pain
Thoracic Paravertebral Block Versus Rhomboid Block for Postoperative Pain Control in Thoracic Surgeries
The main aim of this study is to compare thoracic paravertebral block and rhomboid block for postoperative analgesia and analgesic usage in thoracic surgeries.
- Trial name
- NCT05061667
- Testing
- Thoracic Paravertebral Block, Rhomboid Block
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Koç University
Hemiparesis, Stroke Sequelae
Neural Mechanisms of Motor Recovery With Technology Assisted Training
Stroke is a leading cause of disability that often impairs arm function and activities of daily living. The costs of rehabilitation are significant and practical constraints often limit therapy to the first few months after…
- Trial name
- NCT05560867
- Testing
- robot-assisted training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Maryland, Baltimore
Low Back Pain
Graston Versus Active Release Technique in Females With Non Specific Low Back Pain
Non-specific Low Back Pain defined by tension, soreness, and/or stiffness of the lower back with unknown origins of pain. Reduction in hamstrings flexibility has found to be one of the causes for development of low back pain.
- Trial name
- NCT06877767
- Testing
- Graston Technique, Active Release Technique
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Vestibular Function, Hearing Loss
Evaluation of Executive Functions in Children With Cochleovestibular Deficit
Vestibular system activity supports many functions ranging from gaze stabilization and postural control to high-level cortical functions involving spatial cognition, body perception, verticality perception, orientation…
- Conditions
- Vestibular Function, Hearing Loss, Cognitive Function, Executive Function
- Trial name
- Vestibulex (NCT05665907)
- Testing
- Questionnaire BRIEF (Behavioral Rating Inventory of Executive Function)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sensory Disorders
Occupational Therapy to Treat Children Who Over or Under React to Their Environment
Children with Sensory Modulation Dysfunction (SMD) either over- or under-react to stimuli in their environment. This can cause significant problems with daily activities and may lead to anxiety, poor attention, low self-esteem…
- Trial name
- NCT00006507
- Testing
- Occupational Therapy
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hearing Loss, Ear Diseases
Clinical Evaluation of a Cochlear Implant Sound Processor
This is a prospective within-subjects repeated-measures study that will enroll 24 adult users implanted with a HiResolution Bionic Ear System (HiRes 90K or newer).
- Conditions
- Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases
- Trial name
- NCT04237207
- Testing
- Naída Cochlear Implant Q90 sound processor (Naida CI Q90) & software, 301-M062 sound processor & software
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Advanced Bionics
Coma, Disorder of Consciousness
Development of a Point of Care System for Automated Coma Prognosis
Electroencephalogram/event-related potentials (EEG/ERP) data will be collected from 50 participants in coma or other disorder of consciousness (DOC; i.e., Unresponsive Wakefulness Syndrome [UWS] or Minimally Conscious State…
- Conditions
- Coma, Disorder of Consciousness, Minimally Conscious State, Vegetative State
- Trial name
- NCT03826407
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cholecystitis/Cholelithiasis
Effects of Intravenous Ibuprofen on Acute Pain After Laparoscopic Cholecystectomy
This clinical trial is a medical intervention study to evaluate the necessity and effectiveness of intravenous ibupropan for postoperative acute pain relief after laparoscopic cholecystectomy in benign gallbladder disease.
- Trial name
- NCT05676892
- Testing
- Laparoscopic cholecystectomy
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul St. Mary's Hospital
Low Back Pain
Effect of Lumbar Spinal Fusion Predicted by Physiotherapists
The main purpose of this study is to investigate if improvements in patient self-reported pain, symptoms, function and quality of life 12 months after Lumbar spinal fusion among patients that have good projected prognosis differ…
- Trial name
- NCT03673436
- Testing
- Lumbar spinal fusion
- Where
- Denmark
- Volunteers
- 202 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Cord Injuries, Muscle Pareses
A Novel Combined Neuromodulation Therapy to Enhance Balance and Neuroplasticity
Many people with partial damages in their spinal cord (iSCI) have physical impairments such as muscle paralysis in legs which make standing balance difficult.
- Conditions
- Spinal Cord Injuries, Muscle Pareses, Fall
- Trial name
- NCT05940636
- Testing
- Activity-based rehabilitation+electrical stimulation
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University Health Network, Toronto
Migraine
Oral Dexamethasone for Treatment of Migraine
The aim of this project is to determine if a single dose of oral dexamethasone at the time of discharge from the emergency department (ED) [after successful treatment] prevents rebound headache.
- Trial name
- NCT00216736
- Testing
- Dexamethasone
- Where
- Australia
- Volunteers
- 63 people
- Sponsor
- The Joseph Epstein Centre for Emergency Medicine Research
Chronic Pain Due to Injury, Acute Pain
Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players
This study will investigate the effects of an exercise intervention on retired American professional football (APF) players. A total of 20 retired APF players (≥ 18 years of age), who suffer from chronic pain, will be enrolled.
- Conditions
- Chronic Pain Due to Injury, Acute Pain, Depression, Brain Injuries
- Trial name
- GH-APF (NCT04822311)
- Testing
- Experimental: Investigate the effects of an exercise intervention on retired APF players
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Illinois Chicago
Prader-Willi Syndrome
Clinical Study of Diazoxide Choline Controlled-Release Tablet (DCCR) in Patients With Prader-Willi Syndrome
This is a single-center, open-label, single-arm study with a double-blind, placebo-controlled, randomized withdrawal extension. Patients are initiated on a DCCR dose of about 1.5 mg/kg (maximum starting dose of 145 mg) and are…
- Trial name
- NCT02034071
- Testing
- DCCR
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Essentialis, Inc.
Retinopathy of Prematurity
Sucrose Analgesia for the Reduction of Pain During Retinopathy of Prematurity Screening
Retinopathy of Prematurity (ROP) screening is one of many potentially painful diagnostic and therapeutic procedures performed routinely on preterm infants in the Neonatal Intensive Care Unit.
- Trial name
- NCT00921544
- Testing
- Sucrose, Sterile water
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Coombe Women and Infants University Hospital
Autism Spectrum Disorder, Autism
Halliwick Hydrotherapy and Snoezelen
The aim of this study was to evaluate the effectiveness of the Halliwick concept in the adapted Snoezelen multi-sensory environment, in the gross mobility of children belonging to the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Autism, Sensory Disorder
- Trial name
- NCT05134844
- Testing
- Hydrotherapy- Snoezelen, Snoezelen
- Where
- Greece
- Volunteers
- 53 people
- Sponsor
- University of Thessaly
Pain
Analgesic and Antihyperalgesic Effects of Morphine and Buprenorphine
Tissue injury is associated with pain from the injured site (primary hyperalgesia) and pain from non-injured tissue in the vicinity of the trauma (secondary hyperalgesia).
- Trial name
- PASORII (NCT01296334)
- Testing
- morphine LO, Morphine Hi, Buprenorphine LO
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- mads u werner
Dry Needling Technique, Neck Pain Musculoskeletal
How Dry Needling at the Neck Affects Shoulder Movement, Strength, Pain, and Shoulder Circulation
Segmental facilitation, originally proposed by Korr in the 1950s, suggests that certain spinal segments can become hyperexcitable, leading to chronic pain development.
- Conditions
- Dry Needling Technique, Neck Pain Musculoskeletal, Shoulder Pain, Neck Pain
- Trial name
- NCT06705634
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Texas Woman's University
Sleep Deprivation, Aging
The Peripheral Blood Multi-Omics Study on Sleep Loss
Sleep plays a role in cognitive processes such as memory processing, attention processing, and overall cognitive function. In recent years, the bidirectional relationship between sleep loss and aging, as well as related…
- Conditions
- Sleep Deprivation, Aging, Alzheimer Disease, Healthy Lifestyle
- Trial name
- NCT06492109
- Testing
- Sleep manipulation
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Tinnitus, Anxiety
Mindfulness Based Tinnitus Reduction (MBTR): A Symptom Perception Shift Program
This study is a randomized, controlled trial of Mindfulness Based Tinnitus Reduction (MBTR) vs. Treatment As Usual (TAU). This study aims to determine patient's benefit from participating in an 8-week MBTR program as measured by…
- Conditions
- Tinnitus, Anxiety, Depression
- Trial name
- MBTR (NCT01229709)
- Testing
- Mindfulness Based Tinnitus Reduction
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Chronic Pain
Defense Health Agency- Development of a Medical Device Utilizing an EEG-Based Algorithm for the Objective Quantification of Pain
PainQx, with the support of the Department of Defense (Contract #W81XWH-21-C-0034), is conducting a study to collect electroencephalography (EEG) data from people with chronic pain in order to develop algorithms than will…
- Trial name
- PQXDOD1 (NCT05215184)
- Testing
- Zeto WR19 EEG Recording
- Where
- 5 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- PainQx, Inc
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