Clinical trials: Neurological Condition
Back Pain, Neuralgia
Evaluation of Spinal Cord Stimulation Pulse Rate On Clinical Outcomes
Clinical study to estimate the optimal frequency for stimulation of the spinal cord to achieve relief from back pain.
- Trial name
- PROCO (NCT02549183)
- Testing
- Boston Scientific PRECISION Spinal Cord Stimulator System
- Where
- 3 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Bariatric Surgery Candidate, Morbid Obesity
Erector Spinae Plane Block Versus Opioid Based General Anesthesia During Laparoscopic Bariatric Surgery
bilateral continuous erector spinae plane blockade may represent a valuable alternatives to thoracіc epidurals analgaesіa in treatment of thoracic neuropathic pain.
- Conditions
- Bariatric Surgery Candidate, Morbid Obesity, Visceral Pain
- Trial name
- NCT03798522
- Testing
- bilateral ultrasound guided erector spinae plane block, Nalbuphine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hearing Disorders, Hearing Loss, Sensorineural
Subjective Evaluation of a Sound Processing Method for Hearing Aids on Auditory Distance Perception
Within the course of this study, a signal processing feature has been developed at Ecole Polytechnique Fédérale de Lausanne (EPFL), in collaboration with Sonova AG, in order to enhance the listening experience with remote…
- Trial name
- EXTEND (NCT03512951)
- Testing
- Digital signal processing algorithms
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Dry Eye
Effect of Povidone-iodine 5% Vs 1% on the Ocular Surface in Intravitreal Injections of Anti-VEGF
Objective and subjective comparison between the use of povidone-iodine 1% vs 5% as antiseptic in patients that need anti-VEGF intravitreal injection
- Trial name
- anti-VEGF (NCT06710951)
- Testing
- Change of normal concentration of povidone-iodine 5% to 1%
- Where
- Mexico
- Volunteers
- 88 people
- Sponsor
- José Gerardo García Aguirre
Cerebrospinal Fluid Leak
The Efficacy and Safety of a Latest Dural Substitute
This prospective, multi-center, randomized, parallel-controlled clinical trial was designed to evaluate the efficacy and safety of Lyoplant Onlay in repairing cerebral dura mater. DURAFORM was regarded as the control group.
- Trial name
- ESLO (NCT04490629)
- Testing
- Lyoplant Onlay, DURAFORM
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Chronic Heart Failure
TELEREHAB-BR: Cardiovascular Rehabilitation Models Trial
Introduction: Cardiovascular diseases remain the leading cause of mortality worldwide. Despite the proven effectiveness of cardiac rehabilitation (CR) programs, adherence remains unsatisfactory, especially in public healthcare…
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Chronic Heart Failure, Acute Coronary Syndromes (ACS)
- Trial name
- TELEREHAB-BR (NCT07734831)
- Testing
- Hybrid Cardiac Telerehabilitation, Traditional Center-Based Cardiac Rehabilitation (TCR), Usual Care Group
- Where
- Brazil
- Volunteers
- 219 people
- Sponsor
- University of the State of Santa Catarina
Postoperative Pain, Obesity
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration…
- Conditions
- Postoperative Pain, Obesity, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA-MG (NCT07077031)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital HM Nou Delfos
Laparoscopic Cholecystectomy, Postoperative Pain
Local Infiltration With Levobupivacaine During Laparoscopic Cholecystectomy
Randomized controlled trial on laparoscopic cholecystectomy. Interventional group: preincisional infiltration with levobupivacaine. Control group: no local infiltration.
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Local Infiltration, Levobupivacaine
- Trial name
- NCT04697329
- Testing
- Preincisional infiltration with levobupivacaine
- Where
- Spain
- Volunteers
- 233 people
- Sponsor
- Hospital Universitario de Móstoles
Usher Syndrome
Clinical and Genetic Examination of Usher Syndrome Patients' Cohort in Europe
This study aims to characterize Usher patients in order to correlate this data with genetic information. Tasks: Standardization and improvement of Usher syndrome diagnosis: refine and elaborate special tests of visual and…
- Trial name
- EURUSH (NCT01954953)
- Where
- 6 sites in France, Germany and 2 more
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Pain, Postoperative, Cardiac Surgery
Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery
The primary objective of this study is to determine if the addition of PECS2 block provides superior post-operative analgesia for cardiac surgery patients after midline sternotomy compared to only standard-of-care post-operative…
- Trial name
- NCT04282239
- Testing
- PECS2 block, Ropivacaine 0.5% Injectable Solution, Lidocaine Epinephrine
- Where
- United States
- Sponsor
- NYU Langone Health
Neuropathic Pain, Spinal Cord Injuries (SCI)
High-frequency Alternating Current Stimulation for Neurophatic Pain in Spinal Cord Injury
To investigate the safety and effectiveness of transcutaneous electrical stimulation with 40 kHz alternating currents combined with standard treatment compared to placebo electrical stimulation plus standard treatment for…
- Trial name
- NCT07359677
- Testing
- Active group 40 kHz
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Castilla-La Mancha
Pelvic Girdle Pain, Diastasis Recti and Weakness of the Linea Alba
The Association Between Pelvic Floor Muscle Function, Diastasis Recti and Postpartum Pelvic Girdle Pain - a Matched Case Control Study.
Background: Pregnancy-related pelvic girdle pain (PGP) can appear during pregnancy, directly after labour or can be delayed to 3 weeks postpartum.
- Conditions
- Pelvic Girdle Pain, Diastasis Recti and Weakness of the Linea Alba, Pelvic Floor Disorders
- Trial name
- NCT04757077
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Chronic Pain
OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients
This is an open-label, randomized, single-dose, parallel group study. The objectives of this study are to assess pharmacokinetics of oxycodone and naloxone from oxycodone/naloxone (OXN) prolonged release (PR) tablet 5/2.5 mg (OXN…
- Trial name
- NCT02880475
- Testing
- OXN PR tablet
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Rotator Cuff Injury
Rehabilitation After Rotator Cuff Repair
A new postoperative regimen with a new bandage technique after surgery results in a better shoulder function and quality of life after surgery - than traditional postoperative regimen with shoulder lock and abductor cushion.
- Trial name
- NCT02261701
- Testing
- Early mobilization, Post surgery shoulder lock
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Uppsala University
Low Back Pain
Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.
The purpose of this graduate student research study is to compare the effects of low-load blood flow restriction training (LL-BFR) and heavy-load training (HLT) in high-volume rowers with mild low back pain or recurrent low back…
- Trial name
- NCT07130812
- Testing
- blood flow restriction, Heavy load resistance training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Pain Intensity Assessment, Interscalene Nerve Block
Comparison of Interscalene and Anterior Shoulder Capsule Block
Due to the development and easy availability of ultrasonography devices, regional nerve blocks are routinely used by anesthesiologists among multimodal analgesia techniques.
- Conditions
- Pain Intensity Assessment, Interscalene Nerve Block, Shoulder Anterior Capsule Block (SHAC Block), Pericapsular Nerve Group Block (PENG)
- Trial name
- NCT06827912
- Testing
- Interscalene Nerve Block, Shoulder Anterior Capsule Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Amasya University
Coronary Disease
Anticoagulation With rNAPc2 to Eliminate MACE/TIMI 32
The primary focus of this study is to explore the safety of a range of doses of rNAPc2 in subjects who are managed in hospitals that most typically practice an early invasive strategy (catheterization during the index admission).
- Trial name
- NCT00116012
- Testing
- rNAPc2
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
Impact of Septoplasty on Headache
Impact of Septoplasty on Headache
Impact of septoplasty on headache if there is improvement or changes in headache severity before and after operation
- Trial name
- NCT07894575
- Testing
- Septoplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Pain
Oxycodone User Registry (OUR)
The purpose of this study is to describe clinical and demographic characteristics of patients receiving prescription medications containing oxycodone immediate release (OXYRX), to characterize patient and prescriber perceptions…
- Trial name
- NCT00978328
- Testing
- oxycodone immediate release (OXYRX)
- Volunteers
- 827 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Post-surgical Pain
Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery
The objectives of this study are to evaluate the safety and analgesic efficacy of a single preoperative intrathecal administration of AYX1 Injection in patients undergoing unilateral total knee arthroplasty.
- Trial name
- NCT02807428
- Testing
- AYX1 Injection 660 mg/6 mL
- Where
- 9 sites in United States
- Volunteers
- 210 people
- Sponsor
- Adynxx, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.