Clinical trials: Neurological Disease
Mindfulness, Caregivers
Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers
The proposed two-arm randomized waitlist-controlled trial will use a mixed-methods design to investigate the effects of dyadic mindfulness on physio-psycho-spiritual outcomes in people with Parkinson's Disease (PwPD) and their…
- Conditions
- Mindfulness, Caregivers, Movement Disorders, Neurodegenerative Disease
- Trial name
- NCT06821230
- Testing
- Dyadic mindfulness
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Generalized Myasthenia Gravis
Safety and Efficacy Study of RA101495 in Subjects With Generalized Myasthenia Gravis
The purpose of the study is to evaluate the safety and efficacy of RA101495 in patients with generalized Myasthenia Gravis (gMG).
- Trial name
- NCT03315130
- Testing
- zilucoplan (RA101495)
- Where
- 30 sites in United States, Canada
- Volunteers
- 45 people
- Sponsor
- Ra Pharmaceuticals
Dementia
The INSPIRE -Faith Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement
The INSPIRE-Faith Study, initiated by the Healthy Minds Initiative, is a community-based research project aimed at demonstrating the impact of lifestyle factors on cognitive health and the prevention of dementia.
- Trial name
- INSPIRE -Faith (NCT06741865)
- Testing
- Lifestyle Intervention, Standard Health Education
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Healthy Minds Initiative
Soft Tissue Anesthesia (Numbness)
Safety and Efficacy Study of NV-101 in Dental Patients
The purpose of this study was: to determine if NV-101 accelerates recovery from numbness compared to placebo to evaluate safety of NV-101
- Trial name
- NCT00154167
- Testing
- NV-101 (phentolamine mesylate solution)
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Novalar Pharmaceuticals, Inc.
Oral Health, Malnutrition
The Effects of Technological Oral Health Management
The goal of interventional study is to for the elderly who have poor chewing and eating ability after installing removable dentures through the intervention of oral mastication training and texture and diet education, the effects…
- Conditions
- Oral Health, Malnutrition, Dysphagia, Sarcopenia
- Trial name
- NCT06529900
- Testing
- oral mastication training, texture and diet education
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chang Gung University of Science and Technology
Congenital Toxoplasmosis
Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital Toxoplasmosis
Toxoplasmosis is a benign disease in healthy adults, but can be serious in the case of contamination during pregnancy: the parasite can pass through the placental barrier and infect the foetus.
- Trial name
- TOSCANE (NCT01202500)
- Testing
- reducing treatment to 3 months, registered length of treatment
- Where
- France
- Volunteers
- 302 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hypoxic-ischemic Encephalopathy
Neonatal Erythropoietin in Asphyxiated Term Newborns
The purpose of this study is to determine the safety and pharmacokinetics of moderate to high doses of erythropoietin in newborn infants with birth asphyxia.
- Trial name
- NEAT (NCT00719407)
- Testing
- erythropoietin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Francisco
Multiple Sclerosis, Nurse's Role
The Effect of Nurse Practitioner (NP-led) Care Upon Mood in People With Multiple Sclerosis
MS is the leading cause of non-traumatic disability in young adults. Canada and Alberta, have the highest prevalence of people with multiple sclerosis (PwMS) in the world.
- Trial name
- NCT04388592
- Testing
- Nurse Practitioner (NP) Led Care Arm
- Where
- Canada
- Volunteers
- 248 people
- Sponsor
- University of Alberta
Blast Injuries, Traumatic Brain Injury
The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure
Brain injury from explosive blast is a prominent feature of contemporary combat. Although protective armor and effective acute medical intervention allows soldiers to survive blast events, a growing number of veterans will have…
- Conditions
- Blast Injuries, Traumatic Brain Injury, Post-Traumatic Stress Disorders
- Trial name
- NCT00631436
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Center for Veterans Research and Education
Intellectual Disability, Developmental Disability
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings is a research study aimed at developing, implementing, and evaluating a…
- Conditions
- Intellectual Disability, Developmental Disability, Axis I Diagnosis, Mental Illness
- Trial name
- NCT04726371
- Testing
- Generic Best Practices, Tailored Best Practices
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV Seropositivity
Assessment of Age-related Hearing Loss in HIV-1 Patients
The ageing process is known to be accelerated in HIV-infected patients, compared to the general population. Normal age-related hearing loss (presbyacusia) is a frequent phenomenon, affecting more than 70% of people above 65…
- Trial name
- HELO (NCT02154971)
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Migraine
A Study of M207 With Intranasal Zolmitriptan in Healthy Volunteers
This is a single-center, open-label, randomized, four-way crossover study. Each subject will receive each of the four study treatments once, followed by in-clinic monitoring and extensive blood sample collection for…
- Trial name
- NCT03708744
- Testing
- A: M207 3.8mg, 30 min, upper arm, B: M207 3.8 mg, 30 min, thigh, C: M207 3.8 mg, 1 hr, upper arm
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zosano Pharma Corporation
Hemiplegia,Stroke, Respiratory, Neurophysiological Facilitation Techniques
The Effect of Neurophysiological Facilitation Techniques on Respiratory in Stroke
Hemiplegia is a disease with many complications in its clinical course. One of these complications is respiratory dysfunction. It is aimed to determine the respiratory function problems of patients with hemiplegia and to…
- Trial name
- NCT05601934
- Testing
- Neurophysiological Facilitation Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istinye University
Cerebral Palsy (CP), Activities of Daily Living
NAO Robot in Pediatric Occupational Therapy
Cerebral Palsy (CP) is a non-progressive neurological disorder that affects movement and posture, often impairing upper extremity function and daily activity performance.
- Trial name
- NAO Robot (NCT07283211)
- Testing
- Occupational Therapy Intervention, NAO Robot-Assisted Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ankara Medipol University
Stroke
Effects of Cerebrolysin Combined With Rehabilitation on Motor Recovery in Stroke
This study, E-COMPASSII is a phase IV clinical trial designed as a multicenter, randomized, double-blind, placebo-controlled, parallel-group study. This study will enroll 80 subacute stroke patients with severe motor involvement.
- Trial name
- NCT02768571
- Testing
- Cerebrolysin
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Sarcopenia, Child Development
Determination of Reference Values for Handgrip Strength and Bioimpedance Values in Healthy Turkish Children
In this study, our aim is to determine the reference values for the handgrip force and bioimpedance values in healthy Turkish children.
- Trial name
- NCT06001931
- Testing
- handgrip force and bioimpedance values in healthy Turkish children.
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Diabetes, Memory Impairment
Strengthening, Engaging, and Empowering Dyads Through Nutrition & Wellness
A meta-analysis of over 2.3 million individuals in 14 studies showed that individuals with type II diabetes (T2DM) are at a 60% increased risk for development of any dementia compared to those without T2DM.
- Trial name
- SEED (NCT06473129)
- Testing
- Food for Life Culinary Workshops
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Montefiore Medical Center
Endometriosis, Pain
Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain
The goal of this research is to improve pain outcomes for the over 500K Canadian women, girls and gender-diverse individuals who are newly diagnosed with endometriosis each year.
- Trial name
- NCT06333353
- Testing
- Real RepetitiveTranscranial Magnetic Stimulation 5 sessions, Real RepetitiveTranscranial Magnetic Stimulation 10 sessions
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- University of Ottawa
Parkinson Disease, Healthy
Rapid dEvice Testing pROtocol for Parkinson's Disease
This is an 8 week observational study to evaluate the feasibility of using remote monitoring technologies in future studies of PD.
- Trial name
- RETRO-PD (NCT04675853)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- HealthMode Inc.
Epileptic Seizure, Intracranial Tumor
Our Anesthesia Experience During MRI Scan
In this study we aim to investigate the relationship between our anesthesia practice and post procedure complications after MRI scanning with sedation. This is a retrospective, single center observational study.
- Conditions
- Epileptic Seizure, Intracranial Tumor, Intracranial Hypertension, Intracranial Aneurysm
- Trial name
- NCT03123302
- Where
- Turkey (Türkiye)
- Volunteers
- 977 people
- Sponsor
- Akdeniz University
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