Clinical trials: Neurological Disease
Syndrome, Down
Effects of Kendall Exercise VS Gong's Mobilization on Pain, Range of Motion, Function, and Strength in Cases With UCS
The effectiveness of kendall exercise vs. gong's mobilization for alleviating pain with improvment in range of motion, function and strength in cases with upper cross syndrome, assessed by dividing 44 patinets in two groups as…
- Trial name
- NCT06486207
- Testing
- Gong's mobilization, Kendall Exercise
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University
Alzheimer's Disease
A Community-Based Screening Program to Identify Participants at High Risk for Amyloid Pathology
The primary purpose of this study is to identify participants with or without symptoms of Alzheimer's Disease (AD) that are at high risk for brain amyloid pathology using blood-based biomarkers.
- Trial name
- NCT06043700
- Testing
- No Intervention
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Eisai Limited
Huntington Disease
Benchmarking Integrated Care for People Living With Huntington's Disease in England
The survey and full study information can be accessed here: https://southampton.qualtrics.com/jfe/form/SV_8iEedDJZy4xaiI6 The goal of this anonymous survey is to benchmark integrated care from the perspective of service users in…
- Trial name
- Integrate-HD (NCT05828992)
- Testing
- No intervention administered
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Cerebral Palsy
Implementation of a New Motor Skill Learning Therapeutic Device in Children With Cerebral Palsy Rehabilitation
Study of the efficiency of a new interactive interface to apply all the therapeutic principles of motor skill learning used in high dosage intensive interventions.
- Trial name
- NCT03930836
- Testing
- Hand Arm Bimanual Intensive Therapy Including Lower Extremities, Conventional physical and occupational therapy
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Université Catholique de Louvain
Encephalitis
SouthEast Asia Encephalitis Project
Encephalitis, an acute inflammation of the central nervous system associated with neurologic dysfunction is of public health concern worldwide, because of its high mortality and neurological sequelae rates.
- Trial name
- SEAe (NCT04089436)
- Testing
- CSF sampling, Blood sampling, Nasopharyngeal and rectal sampling
- Where
- 7 sites in Burma, Cambodia and 2 more
- Volunteers
- 800 people
- Sponsor
- Institut Pasteur
Transcatheter Aortic Valve Implantation (TAVI), Aortic Valve Stenosis
Clinical Feasibility and Evaluation Study of POINT-GUARD Embolic Protection Device During TAVR (GUARDIAN)
The purpose of this study is to assess the feasibility and safety of the Transverse Medical, Inc. Point-Guard device. This feasibility study is a limited clinical investigation of the Point-Guard device.
- Conditions
- Transcatheter Aortic Valve Implantation (TAVI), Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement
- Trial name
- GUARDIAN (NCT06962371)
- Testing
- cerebral embolic protection
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Transverse Medical, Inc.
Cerebral Palsy
Balance and Posture in Adults With Cerebral Palsy
The results of this study will have an impact upon public heath policy as adults with cerebral palsy (CP) present a growing and underserved population in the United States.
- Trial name
- NCT01585571
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Temple University
Chronic Heart Failure, Obstructive Sleep Apnea
CPAP and Physiotherapy for Heart Failure and Sleep Apnea in the Elderly
This study evaluates whether adding physiotherapy (including herbal medicine, acupuncture, and Tuina massage) to standard continuous positive airway pressure (CPAP) therapy can provide superior benefits compared to CPAP alone for…
- Trial name
- NCT07061171
- Testing
- Continuous Positive Airway Pressure, Herbal Decoction, Acupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Weihua Peng
Post-treatment Lyme Disease Syndrome, Chronic Pain
Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain
This study will investigate the effectiveness of the Sana Pain Reliever (Sana PR) at reducing chronic pain. The Sana PR is a device comprised of one main component (Mask with Earbuds) and two ancillary components (Charger and…
- Trial name
- NCT06655844
- Testing
- Sana Pain Reliever
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke
Effectiveness of Two Techniques in Injection Site Spotting for Botulinum Toxin Injections: Echography or Electro Stimulation.
Botulinum toxin injections are an effective treatment of limb spasticity after stroke. Different tracking techniques are used to locate a proper injection spot.
- Trial name
- NCT01935544
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Surgery, Cardiac
Incidence of Postoperative Persistent Diaphragmatic Dysfunctions in Cardiac Surgery
Postoperative respiratory complication is a common complication that occurs in 6% of patients after cardiac surgery and increases morbidity and mortality and hospital length of stay.
- Trial name
- INDYD (NCT04276844)
- Testing
- Ultrasonography using the two-dimensional (2D) mode, Respiratory Functional Explorations
- Where
- France
- Volunteers
- 157 people
- Sponsor
- CMC Ambroise Paré
Wounds and Injuries, Cancer Pain
Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds
The goal of this clinical trial is to compare in compare pain reduction in patients with malignant wounds using morphine gel or lidocaine gel.
- Conditions
- Wounds and Injuries, Cancer Pain, Cancer, Breast, Cancer Head Neck
- Trial name
- MorphineGEL (NCT05800834)
- Testing
- Morphine Sulfate, Lidocaine Hcl 2% Jelly
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Glioma, Glioblastoma
Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions
This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intra- and post-operative microdialysis during neurosurgery for central nervous system…
- Conditions
- Glioma, Glioblastoma, Metastatic Malignant Neoplasm in the Brain
- Trial name
- NCT04047264
- Testing
- Microdialysis, Magnetic Resonance Imaging, Computed Tomography
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Cerebral Hemorrhage, Brain Hemorrhage
MIND: Artemis in the Removal of Intracerebral Hemorrhage
The primary objective of this multicenter randomized controlled study is to compare the safety and efficacy of minimally invasive hematoma evacuation with the Artemis Neuro Evacuation Device to best medical management for the…
- Conditions
- Cerebral Hemorrhage, Brain Hemorrhage, Cerebral Parenchymal Hemorrhage, Intracerebral Hemorrhage
- Trial name
- NCT03342664
- Testing
- Artemis + Medical Management, Best Medical Management Alone (MM)
- Where
- 33 sites in United States, Austria and 2 more
- Volunteers
- 236 people
- Sponsor
- Penumbra Inc.
Episodic Migraine
Study of Efficacy and Safety of AMG 334 in Adult Episodic Migraine Patients
This study is to evaluate the efficacy and safety of AMG334 in adult patients with episodic migraine
- Trial name
- EMPOwER (NCT03333109)
- Testing
- Erenumab
- Where
- 81 sites in Argentina, India and 9 more
- Volunteers
- 900 people
- Sponsor
- Novartis Pharmaceuticals
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Acute Myocardial Infarction, Chest Pain
Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department
This is a multi-center study to assess the diagnostic accuracy of the Troponin I assay in the Biosite Triage Cardio3 Panel at the point-of-care (POC) in adults presenting to the emergency department with possible acute myocardial…
- Conditions
- Acute Myocardial Infarction, Chest Pain, Acute Coronary Syndrome
- Trial name
- ESTIMATE (NCT00907231)
- Where
- 6 sites in United States
- Sponsor
- Abbott RDx Cardiometabolic
Stroke, Spasticity
The Use of Photobiomodulation in the Treatment of Spasticity After Stroke.
Stroke is a non-progressive and permanent syndrome in adults, with approximately 60% of patients presenting with spastic hemiparesis.
- Conditions
- Stroke, Spasticity, Photobiomodulation, NIRS
- Trial name
- DarbarIllora (NCT07784231)
- Testing
- Photobiomodulation Therapy, Standard Multidisciplinary Rehabilitation Program for Spasticity
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Nove de Julho
PARKINSON DISEASE (Disorder), Parkinsonism or Parkinson's Disease Nos
Strength and Dual-Task on Sarcopenia in People With Parkinson's Disease
Parkinson´s disease and parkinsonian syndromes are associated with progressive motor and non-motor impairments that may compromise functional independence and quality of life.
- Trial name
- SARCOPARKINSON (NCT07907302)
- Testing
- Nutricional Education and General Exercise Guidelines, Progressive Resistance Training With Cognitive Dual-Task Training, Progressive Resistance Training With Cognitive Dual-Task and Inestability Training
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Valencia
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