Clinical trials: Neurological Disease
Neurological Disorder
Evaluation on Standardized Circuits of the Interest of a Robotic Module of Assistance to the Driving
The device that is the subject of this investigation is a robotic assistance module for driving a semi-autonomous electric wheelchair.
- Trial name
- SWADAPT2 (NCT04259151)
- Testing
- Electric wheelchair with activated assistance module, Electric wheelchair with assistance module not activated
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Pôle Saint Hélier
Surgery, Surgery--Complications
Patterns and Outcomes of Neurosurgery in England Over a Five-year Period
Neurosurgical practice has seen many important changes over several decades with advances in treatments and the types of patients treated.
- Conditions
- Surgery, Surgery--Complications, Neurological Morbidity, Neurological Diseases or Conditions
- Trial name
- NCT05097066
- Testing
- Neurosurgical procedure
- Volunteers
- 371,418 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Neurological Disorders
Muscle Delay Characterization
Functional electrical stimulation (FES) induced cycling is a common rehabilitative therapy. Closed-loop FES control holds the promise to improve rehabilitation procedures.
- Trial name
- NCT04094571
- Testing
- Functional Electrical Stimulation (FES) Control Protocol, Functional Electrical Stimulation (FES) Angle Protocol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Covid19, Neurological Disorder
COVID-19 Versus Neurological Impairment, Physical Activity, Social Contacts and Education
The research will make it possible to assess patients who recovered from COVID-19 for the incidence of neurological problems (impaired balance, gait, coordination, concentration and attention), and changes in the quality of life…
- Conditions
- Covid19, Neurological Disorder, Balance; Distorted, Gait Disorders, Neurologic
- Trial name
- NCT04934085
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Stroke, Parkinson' s Disease, Neurological Impairments, Tele-rehabilitation
Challenges Faced By Neurophysiotherapist While Consultation Through Tele-rehabilitation
Being the most important stakeholder of such a vulnerable population, the neuro physiotherapist faced a lot of difficulties while consulting and assessing patients with neurological impairments.
- Trial name
- NCT04988763
- Testing
- Opinions about tele-rehabilitation for consulting a clients with neurological impairments
- Where
- India
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
Stroke, Acute, TBI
Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placement
There is currently no prospective study analyzing the effect of tracheostomy with bedside simultaneous gastrostomy versus tracheostomy with delayed gastrostomy placement (TSG versus TDG) on the outcomes of neurocritically-ill…
- Conditions
- Stroke, Acute, TBI, Neuromuscular Diseases, Status Epilepticus
- Trial name
- BEGASTON (NCT04758052)
- Testing
- Timing of placement
- Where
- United States
- Sponsor
- University of Mississippi Medical Center
Neurological Disorder
Monitoring Physical Activity in Hispanic Women With Chronic Neurological Disorders
The primary goal of this proposal is to demonstrate the feasibility of using a Fitbit charge to monitor and promote physical activity in a diverse population of Hispanic women with chronic neurological disorders.
- Trial name
- NCT04820153
- Testing
- Physical Activity Monitoring Device, Lifestyle Redesign Coaching
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Autoimmune Encephalitis, Paraneoplastic Neurological Syndrome
HLA Analysis in Autoimmune Encephalitis and Related Disorders: Part II
Autoimmune encephalitis (AE) are characterized by subacute onset of memory deficits, altered mental status or psychiatric symptoms, frequently associated with seizures, inflammatory cerebrospinal fluid and in cases with prominent…
- Trial name
- ICARE-II (NCT04823728)
- Testing
- Autoimmune encephalitis and paraneoplastic neurological syndromes
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Hospices Civils de Lyon
Healthy Subjects, Magnetic Resonance Imaging
Studying Motor Neuron Tests
Background: People with motor neuron disorders have changes in the parts of the brain that control movement. Some tests that are currently used to study these changes are magnetic resonance imaging (MRI) and transcranial magnetic…
- Conditions
- Healthy Subjects, Magnetic Resonance Imaging, Central Nervous System, Volunteer
- Trial name
- NCT01517087
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neurological Autoimmune Diseases
IA or PE - What is the Best Treatment Option of Steroid Refractory Neurological Autoimmune Diseases
In this prospective controlled monocentric observational study, we assessed safety and efficacy of therapy with IA or PE in patients with neurological autoimmune diseases.
- Trial name
- NCT04687332
- Testing
- Apheresis therapy by Octo Nova Technology (DIAMED, Cologne, Germany)
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- University Medical Center Mainz
Central Nervous System Diseases, Neurological Rehabilitation
Pilot Study Concerning an Intelligent Activity-based Client-centred Training System in Neurorehabilitation
The pilot study was performed to evaluate the usability, credibility and expectancy of an intelligent, activity-based client-centred training system (i-ACT), and the motivation towards its use in neurological rehabilitation over…
- Trial name
- i-ACT (NCT04692311)
- Testing
- an intelligent client-centred task-oriented training, Semi-structured interview
- Volunteers
- 25 people
- Sponsor
- PXL University College
Neurological Diseases, Ischemic Stroke
Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury
The purpose of our study is to determine the safety and efficacy of the combination of erythropoietin (EPO) and granulocyte-colony stimulating factors (G-CSF) in patients with neurological diseases.
- Conditions
- Neurological Diseases, Ischemic Stroke, Hemorrhagic Stroke, Cerebral Palsy
- Trial name
- NCT02018406
- Testing
- Combination injection of EPO and G-CSF, Injection of normal saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
SARS-CoV-2 Infection, Intensive Care Unit Patient
WHO Covid 19 - Neurological Abnormalities in SARS-CoV-2 ICU Patients
The SARS-CoV-2 epidemic is leading to a large number of patients in intensive care units due to severe hypoxemic pneumonia. After an acute phase that may require controlled mechanical ventilation and deep sedation, removal of…
- Conditions
- SARS-CoV-2 Infection, Intensive Care Unit Patient, Neurological Abnormality, Delirium
- Trial name
- NeuroCovid (NCT04643548)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neurological Diseases or Conditions, Stroke, Acute
COVID-19 Prevalence and Cognitive Deficits in Neurological Patients
The purpose is to investigate the COVID-19 prevalence, associated morbidity and long-term cognitive deficits in consecutive patients presenting with acute neurological symptoms
- Conditions
- Neurological Diseases or Conditions, Stroke, Acute, Seizure Disorder
- Trial name
- Neuro-Covid (NCT04377425)
- Testing
- COVID-19 swap test PCR
- Where
- 4 sites in Denmark
- Sponsor
- Aarhus University Hospital
Neurological Diseases or Conditions
Weaning From Mechanical Ventilation in Neurological Patients
After a period of mechanical ventilation, a spontaneous breathing trial is performed before extubation in order to assess the patient's ability to breathe.
- Trial name
- NCT03128086
- Testing
- Protocol-directed weaning
- Where
- Spain
- Volunteers
- 94 people
- Sponsor
- Hospital General Universitario de Castellón
Ischemic Stroke, Neurological Injury
Omega 3 and Ischemic Stroke; Fish Oil as an Option
In this trial, The investigators are going to investigate the improvement of neurological functions and infarced area of the brain in ischemic stroke patients after ingestion of omega 3 products that have high concentrations of…
- Conditions
- Ischemic Stroke, Neurological Injury, Stroke, Acute, Inflammatory Response
- Trial name
- OmegaStroke (NCT04386525)
- Testing
- Omega-3 fish oil
- Volunteers
- 60 people
- Sponsor
- King Fahad Medical City
Neurological Disorder, Orthopedic Disorder
TONEFITreha: Proof of Concept and Usability Study.
The importance of physical activity and exercise-based interventions in neuro-orthopaedic rehabilitation is undisputed. Yet, patients and clinicians do not implement minimally required doses of physical activity in standard…
- Trial name
- TONFITreha (NCT03598101)
- Testing
- TONEFITreha
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- Reha Rheinfelden
Neurological Disorder
Effects of the Application of a Reflex Locomotion Program in the Neurological Hand
The recovery of the function of the hand is one of the most important aspects for patients who have suffered the consequences of neurological damage.
- Trial name
- NCT03890965
- Testing
- Reflex locomoction therapy
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- NUMEN Foundation
Neurological Injury, Stroke
Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce Neurological Injuries After Surgical Coronary Revascularization (CANON): a Randomised, Controlled, Investigator and Patient Blinded Single Center Superiority Trial With Three Parallel Arms.
The objective of this study is to investigate the value of employing the aortic no-touch off-pump coronary artery bypass technique and the practice of carbon dioxide surgical field flooding for the prevention of type 1 and 2…
- Conditions
- Neurological Injury, Stroke, Postoperative Cognitive Dysfunction, Postoperative Delirium
- Trial name
- CANON (NCT03074604)
- Testing
- aortic no-touch OPCABG, OPCABG with partial clamp applying carbon dioxide, OPCABG with partial clamp
- Where
- Poland
- Volunteers
- 192 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Healthy, Cognitive Impairment
Post Hoc Analysis and Clinical Data Collection for Subjects Tested With Brain Network Activation (BNA™) Technology
The study is designed to collect data that will aid in future scientific and engineering exploration of correlations between clinical assessments and BNA scores.
- Conditions
- Healthy, Cognitive Impairment, Neurological Disorder
- Trial name
- NCT03699514
- Testing
- Brain Network Activation (BNA™) technology
- Where
- 4 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd