Clinical trials: Neurological Examination
Multiple Sclerosis, Sarcopenia
Investigation of the Prevalence of Sarcopenia and Dynapenia According to Disease Stage in Patients With Multiple Sclerosis and Evaluation of the Relationship Between Sarcopenia Severity and Clinical and Functional Parameters
This cross-sectional observational study aims to determine the prevalence of sarcopenia and dynapenia across disability stages in patients with multiple sclerosis (MS) and investigate their associations with clinical and…
- Conditions
- Multiple Sclerosis, Sarcopenia, Dynapenia
- Trial name
- MS-Sarcopenia (NCT07842731)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness
fNIRS for Disorders of Consciousness
The goal of this observational study is to learn whether functional near-infrared spectroscopy (fNIRS) can measure brain activity in healthy adults and in people with disorders of consciousness (DoC) in the neuro-intensive care…
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State
- Trial name
- NCT07485361
- Testing
- Functional Near-Infrared Spectroscopy Monitoring
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Sarcopenia, Old Age; Atrophy
Beetroot Juice Resistance Training Older Adults
The present study compared the effects of a nitrate containing beetroot juice supplement (BRJ+Nitrate) vs. a placebo (Control) on total and regional fat free mass, quadriceps muscle strength, lower body mobility, and VO2peak in…
- Trial name
- NCT05460351
- Testing
- BRJ+Nitrate, Control
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Cachexia
Non-Invasive Assessment of Skeletal Muscle Loss in Cancer Patients - Phase II
The overall aim of this research is to develop a non-invasive approach to evaluate the production of 3-methylhistidine (3MH)in cancer patients, as a potential means of determining which patients are at high risk for future…
- Trial name
- 3MH-2 (NCT01694602)
- Testing
- (non-radioactive) Oral deuterated 3-methylhistidine (D-3MH)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- The University of Texas Medical Branch, Galveston
ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD)
Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in Women
This prospective single-center interventional study will include women with angina and non-obstructive coronary arteries. Participants will undergo a standardized invasive coronary assessment combining coronary physiology…
- Conditions
- ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD), Vasospastic Angina
- Trial name
- ANOCA-UY (NCT07593157)
- Testing
- Invasive Coronary Functional and Morphological Assessment, Pharmacological treatment will be individualized according to the invasive coronary phenotype identified. Treatment may include antianginal therapy, vasodilator therapy, endothelial function-targeted
- Where
- Uruguay
- Volunteers
- 50 people
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Neurologic Disorder, Duchenne
Physical Therapy Treatment on Children and Adolescents With Neurological Pathologies
To evaluate the positive effects of a home-based physical therapy intervention added to the usual physical therapy programs performed in children with neurological pathologies that induce sensorimotor impairments that affect…
- Conditions
- Neurologic Disorder, Duchenne, Pediatric Disorder, Sensorimotor Disorder Nos
- Trial name
- NCT05313295
- Testing
- Home-based physiotherapy, Usual Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Almeria
Chronic Pain
A One-year, Open-label Study to Assess the Safety and Effectiveness of Extended Release Tramadol HCl in the Treatment of Chronic, Non-malignant Pain.
The purpose of this study is to assess the safety of tramadol HCl ER following long-term treatment. The study hypothesis is that long-term treatment with tramadol HCl ER is safe and effective for the treatment of chronic…
- Trial name
- NCT00347685
- Testing
- tramadol ER
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Bausch Health Americas, Inc.
Breast Neoplasms, Pain, Chronic
Pain Neuroscience Education and Therapeutic Exercise as a Treatment for Breast Cancer Survivors Living With Sequelae
Introduction: Breast cancer represents the most common type of malignant neoplasm worldwide. Advances in diagnosis and treatment have increased the life expectancy of patients.
- Conditions
- Breast Neoplasms, Pain, Chronic, Kinesiophobia, Breast Cancer
- Trial name
- NCT05452499
- Testing
- Pain neuroscience education and therapeutic exercise
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Universidad Autónoma de Yucatán
Back Problems and Other Musculoskeletal Injuries
Injury Prevention Among Conscripts
The purpose of this clinical trial is to study the effect of neuromuscular training program and regular safety counselling on the risk of musculoskeletal injuries in adolescent conscripts.
- Trial name
- VASTE (NCT00595816)
- Testing
- physical training and counselling
- Where
- 2 sites in Finland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Multiple Sclerosis, Gait Disorders, Neurologic
Walking and Thinking - Brain Activity During Complex Walking in People With Multiple Sclerosis
Every-day life means being part of a complex environment and performing complex tasks that usually involve a combination of motor and cognitive skills.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Neuro-Degenerative Disease, Aging
- Trial name
- NCT05787704
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Karolinska Institutet
Low Back Pain
Clinical Prediction Rule for Clinical Lumbar Instability
The aim of this study is to determine if assessment of additional measures of trunk neuromuscular control will improve the ability to identify patients with low back pain who successfully respond to trunk stabilization exercises.
- Trial name
- NCT01085448
- Testing
- Core Stabilization
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Drexel University
Knee Osteoarthritis, Primary Total Knee Arthroplasty
Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.
The purpose of this study is to learn if using an Interspace between the Popliteal Artery and Capsule of the Knee (iPACK) injection technique (also called a "nerve block") that numbs the nerves going to the back part of the knee…
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain
- Trial name
- NCT03353233
- Testing
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Inactivity, Physical, Treatment Adherence and Compliance
VR vs. Conventional Cycling Exercise for Geriatric Inpatient Physical Activation
The aim of this study is to investigate whether virtual reality assisted stationary cycling exercise results in more physical activity than conventional unsupervised stationary cycling exercise.
- Conditions
- Inactivity, Physical, Treatment Adherence and Compliance, Hospital Acquired Condition, Sarcopenia
- Trial name
- NCT05123638
- Testing
- Virtual reality cycling exercise, Unsupervised stationary cycling exercise
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Opioid Use, Post Operative Pain
Comparing Intrathecal Morphine With Erector Spina Plane Block in Open Gastrectomy Surgery
Open gastrectomy causes severe postoperative pain due to wide surgical incisions, retraction of the abdominal wall and direct manipulation of the visceral organs.
- Conditions
- Opioid Use, Post Operative Pain, Pain Assessment Scales
- Trial name
- NCT05706285
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Marmara University
Pain, Chronic, Obstructive Pulmonary Disease
Comparison of Respiratory Muscle, Pain, Functional Performance and Cognitive Status in Obstructive Lung Diseases
In the literature, there are a limited number of studies evaluating postural awareness, cognitive status, respiratory muscle strength and endurance, functional capacity, and pain in people with obstructive pulmonary disease, and…
- Conditions
- Pain, Chronic, Obstructive Pulmonary Disease, Cognitive Impairment, Functional Disturbance
- Trial name
- NCT04048408
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Pain, Peer Review, Health Care
Evaluation of a Interdisciplinary Pain Program Among Patients With Chronic Pain and Frequent Emergency Department Visits
While significant advances in pain management have occurred in the last 20 years, the majority of patients with chronic pain (CP) are unable to access evidence-based treatment at either the primary or tertiary care level.
- Conditions
- Chronic Pain, Peer Review, Health Care, Interdisciplinary Communication
- Trial name
- CIPAP (NCT02237391)
- Testing
- CIPAP Program, Treatment as Usual (TAU)
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Ottawa Hospital Research Institute
Dysmenorrhea, Primary Dysmenorrhea
The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea
Dysmenorrhoea is a condition that negatively affects the quality of life in women of many age groups. In girls with dysmenorrhoea in adolescence, there is an effect on school performance, self-confidence-depression problems and a…
- Trial name
- NCT06398990
- Testing
- Cognitive Exercise Therapy Approach, Yoga, Routine Medical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Acibadem University
Low Back Pain
A Bio-psycho-social Exercise Program (RÜCKGEWINN) for Chronic Low Back Pain in Rehabilitation Aftercare
Background: In chronic back pain, rehabilitation specific aftercare programs, needed for a long-term improvement of pain and functional ability, are absent.
- Trial name
- RÜCKGEWINN (NCT01070849)
- Testing
- educational booklet, IRENA, RÜCKGEWINN
- Where
- 6 sites in Germany
- Volunteers
- 299 people
- Sponsor
- University of Erlangen-Nürnberg
Age - Related Macular Degeneration, Diabetic Retinopathy
A Comparison of the Checkup Vision Assessment System to Standard Vision Assessment Tools
The CLEAR study is testing the level of agreement between visual acuity and Amsler grid testing using a mobile vision testing application, Checkup Study, and standard in office methods.
- Conditions
- Age - Related Macular Degeneration, Diabetic Retinopathy, Metamorphopsia
- Trial name
- CLEAR (NCT02871817)
- Testing
- Paxos Checkup Study Mobile Medical Application
- Where
- 12 sites in United States
- Volunteers
- 143 people
- Sponsor
- Digisight Technologies, Inc.
Analgesia
Assessment of PENG Block Analgesia Versus Intra-articular Infiltration in Hip Prosthesis Surgery
After hip arthroplasty, pain intensity is maximum within the first 6 hours and is then estimated to last between 36 and 72 hours. Pain management (analgesia) after hip prosthetic surgery remains a challenge.
- Trial name
- API (NCT06675916)
- Testing
- PENG Block with lidocaine hydrochloride, Intra-articular infiltration with lidocaine hydrochloride
- Where
- France
- Volunteers
- 60 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
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