Clinical trials: Neurological Examination
Disabilities, Visual Impairment and Blindness (Excl Colour Blindness)
Study Protocol: The Jerte Valley as an Inclusive Outdoor Classroom. Smart and Active Tourism.
To promote the inclusion of people with disabilities, an outdoor intervention will be conducted involving physical activities with adolescents with and without disabilities.
- Trial name
- NCT07609459
- Testing
- Rafting, canoeing and kayaking, Divulgation
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Lower Back Pain
Assessment of Chiropractic Treatment for Low Back Pain and Smoking Cessation in Military Active Duty Personnel.
The purpose of this study is to evaluate the effectiveness of chiropractic manipulative therapy for pain management and improved function in active duty service members with low back pain that do not require surgery.
- Trial name
- NCT01692275
- Testing
- Medical Care + Chiropractic Care, Conventional Medical Care Only
- Where
- 3 sites in United States
- Volunteers
- 750 people
- Sponsor
- RAND
Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2
Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia
PRIME-Ataxia is a randomized controlled trial that aims to determine the feasibility and efficacy of an 8-week telehealth intervention of high intensity aerobic exercise prior to balance training compared to an 8-week telehealth…
- Conditions
- Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6
- Trial name
- PRIME-Ataxia (NCT05826171)
- Testing
- High-Intensity Aerobic Exercise Prior to Balance Training, Low-Intensity Exercise Prior to Balance Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Teachers College, Columbia University
Pain, Acute, Infant, Newborn
The Influence of Skin-to-skin Contact on Cortical Activity During Painful Procedures on Preterm Infants in the NICU
The aim of this study is to examine the effect of SSC compared to sucrose on pain induced activity in the preterm infant brain using: a) series of low intensity experimental stimuli (PinPrick);and b) medically required heel…
- Conditions
- Pain, Acute, Infant, Newborn, Electroencephalography
- Trial name
- iCAPmini (NCT03745963)
- Testing
- Skin-to-skin contact, 24% oral sucrose
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- IWK Health Centre
Neuropathic Pain, Multiple Sclerosis
Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic Pain
This is a comparative drug trial involving patients with clinically definite Multiple Sclerosis and documented neuropathic pain. Patients will be randomized to receive treatment with either paroxetine or pregabalin.
- Trial name
- NCT00291148
- Testing
- paroxetine, pregabalin
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University of Manitoba
Sickle Cell Disease
Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management
Sickle cell disease (SCD) is a common genetic disorder characterized by episodes of pain, yet assessments to identify type, intensity, frequency, and phase of pain among SCD adolescents is lacking.
- Trial name
- NCT03291613
- Testing
- Pinpoint App
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Examination of the Central Autonomic Network
This proposal aims to move the science of chronic pelvic pain (CPP) from simple associations towards an investigation of cause and effect relationships.
- Trial name
- ICECAN (NCT03008382)
- Testing
- Metoprolol Tartrate Oral Tablet, No intervention- observational sub-study
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Spinal Cord Injuries
Single Exercise Session or Meal vs Control in SCI: Case Series
The purpose of this study is to examine the immediate effects of a single exercise session or a high fat/high carbohydrate meal on the physical and mental health of people with a spinal cord injury (SCI).
- Trial name
- NCT03955523
- Testing
- Single exercise bout trial, Single diet trial
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Chronic Pain Syndrome, Peripheral Neuropathic Pain
Protocol Assessment of Motor Cortex rTMS for Treating Neuropathic Pain
Neuropathic pain is frequent and drugs relieves only 50% of the patients. Repetitive transcranial magnetic stimulation (rTMS) at high frequency (HF, usually 10Hz) applied on the primary motor cortex (M1) is an effective treatment…
- Trial name
- CSA3-RTMS (NCT06964243)
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy)
Low Back Pain
The Effectiveness of Telerehabilitation Modalities in Physical Therapy in the Management of Chronic Low Back Pain
Low back pain (LBP), a common disorder, causes disability, functional decline and high health care costs. Patient care programs include specific exercises for promoting function and improving health.
- Trial name
- NCT03756740
- Testing
- telerehabilitation and physical therapy, control
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Postoperative Pain, Acute, Postoperative Pain, Chronic
Postoperative Pain in Patients Undergoing Scheduled Laparoscopic Intestinal Resection Surgery
This observational prospective study aims to evaluate the postoperative analgesic effect of a regional anesthesia thechnique (TAP block) in patients undergoing scheduled laparoscopic intestinal resection for intestinal cancer.
- Trial name
- TAP (NCT05222789)
- Testing
- TAP
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Chronic Low Back Pain (CLBP), Low Back Pain
Chronic Low Back Pain and Osteopathic Manipulation Treatment
The goal of this clinical trial is to learn if adding Osteopathic Manipulative Therapy (OMT) to the usual medical care provided at the VA (usual VA care) improves treatment outcomes in individuals with chronic low back pain…
- Trial name
- NCT07161661
- Testing
- Usual VA Care, Osteopathic manipulative treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Edward Hines Jr. VA Hospital
Marfan Syndrome
Clinical and Psychosocial Factors Associated With Physical Activity Level in Adults With Marfan Syndrome
Background. Marfan syndrome is a genetic connective tissue disorder with cardiovascular and musculoskeletal involvement. Despite clinical advances, many patients exhibit low levels of physical activity, influenced by clinical and…
- Trial name
- NCT07419386
- Testing
- Adults with Marfan syndrome
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- University of Oviedo
Intracerebral Hemorrhage, Neurologic Deficits
Multicenter Registry for Assessment of Markers of Early Neurological Deterioration in Primary Intracerebral Hemorrhage
This multicenter observational study will explore the risk factors of early neurological deterioration(END) in patients with primary and to investigate the association between END and outcome.
- Conditions
- Intracerebral Hemorrhage, Neurologic Deficits, Hemorrhagic Stroke, Hemorrhage
- Trial name
- CATCH (NCT05502874)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Shoulder Musculoskeletal Disorders
Passive Exoskeletons for Assisting Patients With Shoulder Musculoskeletal Disorders
Goal: The clinical investigation aims to evaluate the usability of passive exoskeletons, their impact on daily living activities, and the perceived experience of patients with shoulder musculoskeletal disorders.
- Trial name
- EXOADL (NCT06842017)
- Testing
- Passive Exoskeleton., Shoulder Rehabilitation with Passive Exoskeleton., Usability Assessment and Patient Satisfaction.
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Low Back Pain, Mechanical
Low Back Health Education on Physical Function and Body Awareness in Academicians
This study was planned to investigate the effect of back health education given to academicians on physical function and body awareness.
- Trial name
- NCT05948189
- Testing
- exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Biruni University
Pain
Post-surgical Pain Assessment in Children: Roles of Skin Conductance and Genomics
Pain assessment in infants and toddlers is quite challenging since children in these populations are nonverbal or preverbal and cannot describe the presence and severity of pain that they perceive.
- Trial name
- NCT02534168
- Testing
- Skin conductance monitor for measuring skin conductance
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Milton S. Hershey Medical Center
Diabetes, Visual Impairment
Nonvisual Foot Examination for People With Diabetes and Visual Impairment
Because people who have both diabetes and visual impairment have high risk for foot problems, prevention of ulcers and amputation is a high priority.
- Trial name
- NCT02102958
- Testing
- DSME with Nonvisual Foot Examination, DSME with Usual Foot Examination Instruction
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Case Western Reserve University
Dysarthria
Development of Dual Language (Urdu and English) Digital Software for SA, Management Of Adult Dysarthria
The research focuses on the development of a dual-language (Urdu and English) digital software designed for the self-assessment and management of adult dysarthria patients.
- Trial name
- NCT07129291
- Testing
- Experimental: Dual-Language Dysarthria Self-Assessment and Management Software (D-SAMS)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Superior University
Depression
Assessment of the Effect of Sertaline on the Specific Binding of 123-I MZINT in Healthy Subjects
The overall purpose of this project is to evaluate the effect of sertraline administration on the binding of 123-I mZINT in 10 healthy subjects.
- Trial name
- mZINT (NCT00470925)
- Testing
- 123-I MZINT injection and SPECT imaging
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
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