Clinical trials: Neurological Health
Neuropathic Pain
Spinal Cord Stimulation and Physiotherapy for Treatment of Neuropathic Pain
The study evaluates the combined effect of optimized pharmacological treatment, spinal cord stimulation and physiotherapy on pain relief, health-related quality of life and physical function in patients with neuropathic pain.
- Trial name
- SCS-PHYSIO (NCT03740763)
- Testing
- Spinal Cord Stimulation (SCS), Physiotherapy
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Göteborg University
Pain, Postoperative, Opioid Use Disorder
Patient Engagement in Perioperative Pain Management Project
Previously, the study team evaluated the implementation and effectiveness of the Johns Hopkins Perioperative Pain Program (PPP), which coordinates continuum of care for surgical patients on chronic opioid therapy throughout the…
- Trial name
- NCT05252767
- Testing
- Patient Engagement Tools, Educational Guide
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Johns Hopkins University
Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,
Evaluation of a Regional Electronic Health Information Exchange's Clinical Health Record
The Shared Health CHR™ (Clinical Health Record) offers point-of-care clinical reporting and decision support based primarily on patient claims data aggregated across various health care settings, and is one example of the types…
- Conditions
- Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,, Gastroenteritis, Seizures, and Bacterial Pneumonia)
- Trial name
- NCT00978744
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Glioblastoma, Glioblastoma Multiforme
The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.
The trial is designed as a multicenter randomized controlled study. 246 patients with presumed Glioblastoma Multiforme in eloquent areas on diagnostic MRI will be selected by the neurosurgeons according the eligibility criteria…
- Conditions
- Glioblastoma, Glioblastoma Multiforme, Glioblastoma Multiforme of Brain, Astrocytoma, Grade IV
- Trial name
- SAFE (NCT03861299)
- Testing
- Awake craniotomy, Craniotomy under general anesthesia
- Where
- 5 sites in Belgium, Netherlands
- Volunteers
- 246 people
- Sponsor
- Jasper Gerritsen
Sleep, Pain
Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health
A randomized, blinded, placebo-controlled study of health and wellness product formulations and their effects on overall health
- Conditions
- Sleep, Pain, Depression, Anxiety
- Trial name
- NCT05783232
- Testing
- Health Active Study Product 1.1 Capsules, Health Active Study Product 1.2 Capsules, Health Active Study Product 1.3 Capsules
- Where
- United States
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Acute Pain
Electronic Defaults to Reduce Opioid Prescribing in Emergency Department and Primary Care Settings
The goal of this research is to investigate the impact of changing opioid analgesic prescribing defaults on the quantity of opioids prescribed for acute non-cancer pain in adult primary care and emergency department settings.
- Trial name
- NCT03003832
- Testing
- Change in electronic health record default for new opioid analgesic prescriptions
- Volunteers
- 15,000 people
- Sponsor
- Montefiore Medical Center
Sarcopenia in Elderly, Dynapenia
Reduction in Resistance Training Volume and Neuromuscular Adaptations in Older Adults
The goal of this clinical trial is to evaluate how reducing resistance training volume affects neuromuscular adaptations in older adults aged 60 to 70 years.
- Trial name
- NCT07046130
- Testing
- Resistance Training
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Depression Symptoms, Chronic Pain
Effect of Auricular Press Needle on Improvement of Patient Health Questionnaire-9 (PHQ-9) and Heart Rate Variability (HRV) Patient With Depression Symptoms in Chronic Pain
Depression is characterized by behavioral, cognitive and emotional changes. Depression can have a negative impact on decreasing quality of life because in many cases it occurs long-term.
- Trial name
- NCT06401070
- Testing
- Plesterin, Press needle acupuncture
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Fibromyalgia Syndrome
Effect of Soundscapes on Emotional Distress in Fibromyalgia: a 4×4 Crossover Trial
This study tests whether different types of sounds can help reduce emotional distress in people with fibromyalgia. Fibromyalgia is a condition that causes widespread muscle and joint pain and makes people extra sensitive to…
- Trial name
- FMSounDistress (NCT07231289)
- Testing
- Natural soundscape exposure, Urban soundscape exposure, Broadband sound active control
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Universidad de Granada
Cancer Pain, Opioid Use
Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment
In 2012, more than 14 million cases of cancer were diagnosed worldwide, with the forecast for 2025 exceeding 20 million. Pain is the most critical symptom that accompanies cancer.
- Conditions
- Cancer Pain, Opioid Use, Cost Analysis, Palliative Care
- Trial name
- NCT05558397
- Testing
- Interventional Group (Epidural morphine), Control Group (Oral morphine)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Alfenas
Cerebral Palsy (CP), Pain
EFFECTS OF AROMATHERAPY AND REFLEXOLOGY ON PAIN, SLEEP, AND SATISFACTION IN CHILDREN WITH CEREBRAL PALSY
This randomized controlled trial was conducted to evaluate the effects of aromatherapy and foot reflexology on pain, sleep quality, and parental satisfaction in children with cerebral palsy.
- Conditions
- Cerebral Palsy (CP), Pain, Sleep Disorder (Disorder)
- Trial name
- AROMA-REF CP (NCT07519291)
- Testing
- Aromatherapy, Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hakkari Universitesi
Chronic Pain, Stress, Psychological
WILD 5 Wellness: A 90-Day Intervention (WILD = Wellness Interventions for Life's Demands)
The purpose of this study is to explore the efficacy and feasibility of an integrated, prescriptive, and trackable wellness intervention combining five wellness elements including exercise, mindfulness, sleep, social…
- Conditions
- Chronic Pain, Stress, Psychological, Healthy
- Trial name
- NCT02918513
- Testing
- Wellness Element 1 - Exercise, Wellness Element 2 - Mindfulness, Wellness Element 3 - Sleep Hygiene
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Dyspareunia, Pelvic Pain
Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy
The purpose of this study is to examine the feasibility of adding pre-rehabilitation pelvic health physical therapy to standard of care radiation therapy treatment plan for female patients who have been diagnosed with cervical…
- Conditions
- Dyspareunia, Pelvic Pain, Sexual Dysfunction, Radiation Toxicity
- Trial name
- NCT06059586
- Testing
- Pelvic health therapy, Dilator feasability
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Neurological and Mental Health Conditions, Genetic Susceptibility
Mapping Antenatal Maternal Stress
This study recruits women from early-mid pregnancy and later follows their children after birth, tracking both the mother and child until the child reaches at least 4 years of age.
- Conditions
- Neurological and Mental Health Conditions, Genetic Susceptibility, Socioeconomic Factors, Psychology, Social
- Trial name
- MAMS (NCT07432217)
- Where
- Singapore
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Pain, Intramuscular Injection
The Effect of ShotBlocker on Injection Pain
Shotblocker is an effective approach to reduce injection pain. Generally, injection pain has been studied in children, but reducing injection pain in adults is an important issue.
- Trial name
- NCT05495542
- Testing
- ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bornova No. 25 Mevlana Family Health Center
Hearing Loss, Tinnitus
Hearing Impairment, Cognitive Therapy and Coping
A randomized controlled study with hearing impaired workers, who have voluntarily signed up for an 8 session cognitive therapy (CBT) course The CBT intervention will be compared to a waiting list control group.
- Conditions
- Hearing Loss, Tinnitus, Stress, Psychological, Mental Fatigue
- Trial name
- NCT01206829
- Testing
- 8-session CBTcourse, 8 session cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Sarcopenia, Frailty
Whole Grain Job's Tear, Muscle Health, Blood Glucose and Lipid Level
Background: This investigation aims to explore efficacy of Taiwanese whole grain job's tear on muscle health and blood glucose and lipid levels in community-dwelling older adults.
- Conditions
- Sarcopenia, Frailty, Hyperglycemia, Hyperlipidemia
- Trial name
- NCT06503172
- Testing
- Taiwanese whole grain job's tear (red job's tear), White job's tear
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Physical Activity
Physical Activity in University Students Around COVID-19 Confinement
The period of confinement due to COVID-19 may lead to reduced physical activity levels with negative consequences for health and quality of life in the short and long term, in case the sedentary habits are maintained over time.
- Trial name
- NCT04361019
- Testing
- On-Line Survey
- Where
- Spain
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Pain, Postoperative, Medication Adherence
Pain Medication After Ambulatory Surgery
In Finland, there are no guidelines concerning post-operative pain medication of ambulatory surgery patients. There is a wide variety in drug prescription and medication practices of various doctors and clinics.
- Conditions
- Pain, Postoperative, Medication Adherence, Adverse Drug Event
- Trial name
- NCT03135470
- Where
- Finland
- Volunteers
- 146 people
- Sponsor
- Helsinki University Central Hospital