Clinical trials: Neurological Manifestations
Postsurgical Pain
Efficacy and Safety Study of Ketorolac / Pitofenone / Fenpiverinium for the Treatment of Patients With Pain After Surgical Abdominal and Pelvic Operations
Neospastil (ketorolac tromethamine / pitofenone hydrochloride / fenpiverinium bromide fixed-dose combination) in a form of solution for injections and film-coated tablets has been studied as a treatment for pain after surgical…
- Trial name
- NCT05607641
- Testing
- Ketorolac tromethamine, solution for injection then Neospastil, film-coated tablets, Ketorolac tromethamine, solution for injection then Ketorolac tromethamine, coated tablets, Neospastil, solution for injection then Neospastil, film-coated tablets
- Where
- 14 sites in Ukraine
- Volunteers
- 424 people
- Sponsor
- Darnitsa Pharmaceutical Company
Parkinson's Disease
A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa
The purpose of this study is to achieve approval for the use of carbidopa/levodopa/entacapone in early Parkinson's disease (PD) by demonstrating that when used as initial levodopa therapy in early PD…
- Trial name
- NCT00134966
- Testing
- capsules containing: carbidopa (25 mg), levodopa (100 mg), entacapone (200 mg)
- Where
- 60 sites in United States, Canada and 6 more
- Volunteers
- 493 people
- Sponsor
- Novartis
Migraine
Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment).
- Trial name
- NCT03275922
- Testing
- ZNS
- Where
- 47 sites in United States
- Volunteers
- 374 people
- Sponsor
- Impax Laboratories, LLC
Stroke, Hemiparesis
Fully Remote Use of IpsiHand Device in Hemiparetic Stroke
BCI-REHAB was a randomized clinical trial comparing an at-home brain-computer interface therapy system versus an at-home exercise program for upper-extremity rehabilitation in the chronic phases of stroke.
- Conditions
- Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Brain Computer Interface
- Trial name
- NCT05965713
- Testing
- Neurolutions IpsiHand Upper Extremity Rehabilitation System, Home Exercise rehabilitation regimen Program (HEP)
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Neurolutions, Inc.
Neuropathic Pain
Non Invasive Brain Evaluation and Treatment for Neuropathic Pain
This trial is designed to preliminary evaluate the efficacy and safety of NIBS system for evaluation and treatment of neuropathic pain.
- Trial name
- NIBSNP (NCT02740062)
- Testing
- NIBS system for evaluation and non invasive current stimulation
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- NIBS NeuroScience Technologies
Pain
A Study Comparing Vicodin® CR and NORCO® to Placebo in Subjects With Acute Pain Following Bunionectomy
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended Release Hydrocodone/Acetaminophen and Immediate Release Hydrocodone/Acetaminophen with placebo over a…
- Trial name
- NCT00404222
- Testing
- Hydrocodone/Acetaminophen Extended-Release, Hydrocodone/Acetaminophen Immediate Release (NORCO®)
- Volunteers
- 90 people
- Sponsor
- Abbott
Parkinson Disease, Freezing of Gait
Use of CereGate Therapy for Freezing of Gait in PD
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
- Trial name
- NCT05292794
- Testing
- CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- CereGate Inc.
Parkinson's Disease
Automated Parkinson's Disease (PD) Motor Symptom Assessment for Deep Brain Stimulation (DBS) Programming
The purpose of this study is to evaluate the utility of a portable motion sensor-based system designed to assist with deep brain stimulation (DBS) programming sessions for Parkinson's disease patients.
- Trial name
- NCT01429220
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Chronic Pain, Chronic Pain (Back / Neck)
Combination of Equisetum Arvense and Palmitoylethanolamide (PEA) for the Management of Patients With Chronic Pain in a Before-after Study
Chronic pain is a type of pain that lasts or recurs for a period of more than three months. Due to the physical, psychological, and socio-relational consequences of chronic pain for the person experiencing it, it has been…
- Conditions
- Chronic Pain, Chronic Pain (Back / Neck), Pain (Visceral, Somatic, or Neuropathic), Pain Management
- Trial name
- Assonal®️PEA (NCT07110480)
- Testing
- Supplement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- noiVita Srls
Shoulder Pain, Neck Pain
Low Level Laser Light Therapy and Chronic Neck and Shoulder Pain
The purpose of this study was to determine whether the application of low level laser light therapy to the neck and shoulder region is effective in reducing chronic neck and shoulder pain of musculoskeletal origin.
- Conditions
- Shoulder Pain, Neck Pain, Musculoskeletal Pain, Musculoskeletal Strain
- Trial name
- NCT00929305
- Testing
- Erchonia PL2000
- Volunteers
- 100 people
- Sponsor
- Erchonia Corporation
Intracranial Aneurysm, Subarachnoid Hemorrhage
CorPath® GRX Neuro Study
The primary objective of this study is to evaluate the effectiveness and safety of robotic-assisted endovascular embolization procedures compared to objective performance criteria for traditional, manual operation based on the…
- Conditions
- Intracranial Aneurysm, Subarachnoid Hemorrhage, Headache
- Trial name
- NCT04236856
- Testing
- Robotic Endovascular Procedure
- Where
- 10 sites in Australia, Austria and 4 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Pain
A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy
The purpose of this study is to evaluate effectiveness of a fixed combination of acetaminophen/naproxen sodium compared with placebo for reduction of pain when administered as multiple doses over a 48-hour period.
- Trial name
- NCT05868122
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination
- Where
- 4 sites in United States
- Volunteers
- 143 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Stable Angina
Efficacy and Safety of Monocordil Manufactured by Laboratórios Baldacci
Phase III clinical study for the evaluation of clinic and cardiologic effects of isosorbide mononitrate from the incidence of events (angina episodes). This is an open, comparative, monocentric trial.
- Trial name
- NCT02152579
- Testing
- Isosorbide-5-mononitrate
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- Laboratórios Baldacci S.A
Neoplasms
A Safety and Efficacy Study of Oral Tapentadol Extended-Release in Japanese Participants
The purpose of this study is to evaluate the conversion rate based on the number of participants achieving pain control and safety within 1 week after switching the opioid (morphine-like medications) analgesics (drug used to…
- Trial name
- NCT01309386
- Testing
- Tapentadol ER, Morphine SR
- Where
- 22 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Janssen Pharmaceutical K.K.
Inherited Mitochondrial Disease, Including Leigh Syndrome
Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease
To evaluate safety, tolerability and efficacy of cysteamine bitartrate delayed-release capsules (RP103) administered at a target maintenance dose of 1.3 g/m²/day in two divided doses, every 12 hours, for up to 6 months in…
- Trial name
- MITO-001 (NCT02023866)
- Testing
- Cysteamine Bitartrate
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Amgen
Healthy Volunteers, Muscle Fatigue
Effects of Recoverben® on Recovery After Exhaustive Exercise
The aim of the study is to investigate a pre and post workout supplementation (15 days) with Recoverben® , a Aloysia citriodora extract on recovery after exhaustive exercise.
- Conditions
- Healthy Volunteers, Muscle Fatigue, Muscle Soreness
- Trial name
- NCT02923102
- Testing
- Aloysia citriodora extract, Maltodextrin
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vital Solutions GmbH
Uterine Fibroids, Bleeding
A Clinical Study to Evaluate Safety of the ExAblate 2100 UF V2 System in the Treatment of Symptomatic Uterine Fibroids
The first magnetic resonance-guided focused ultrasound (MRgFUS) treatment of uterine fibroid using the ExAblate 2000 system was performed in 2001.
- Conditions
- Uterine Fibroids, Bleeding, Pain
- Trial name
- NCT01092988
- Testing
- Exablate 2100
- Where
- 4 sites in France, Israel and 2 more
- Volunteers
- 40 people
- Sponsor
- InSightec
Post Operative Pain
OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty
The purpose of this study is to demonstrate that treatment with OXN PR tablets is non inferior to treatment with OXY PR tablets in terms of analgesic efficacy in patients with postoperative pain after knee arthroplasty based on…
- Trial name
- OXN4505 (NCT01083485)
- Testing
- Oxycodone/Naloxone PR 20/10mg or 10/5mg tablets, Oxycodone
- Where
- Finland
- Volunteers
- 137 people
- Sponsor
- Mundipharma Oy
Post-surgical Dental Pain
Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic Efficacy
GlaxoSmithKline will be conducting this trial to compare analgesic efficacy of paracetamol 1000 mg vs 650 mg. The post-surgical dental pain model will be used to evaluate the analgesic efficacy of paracetamol.
- Trial name
- NCT01075243
- Testing
- Paracetamol 1000 mg, Paracetamol 650 mg
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- GlaxoSmithKline
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
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