Clinical trials: Neurological Outcome
Wound Complication, Surgical Wound Infection
Electrocautery Versus Scalpel for Skin Incisions
The aim of this research project is to compare electrocautery to scalpel for laparotomy skin incisions, with the following objectives: 1. To investigate whether electrocautery produces a cosmetically inferior surgical scar. 2.
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain
- Trial name
- NCT01496404
- Testing
- Electrocautery, Scalpel
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- St. Paul's Hospital, Canada
Ischemic Stroke
Sedation Versus General Anesthesia for Endovascular Therapy in Acute Stroke - Impact on Neurological Outcome
The purpose of this study is to evaluate whether general anesthesia or sedation technique is preferable during embolectomy for stroke, measured in terms of three months neurological impairment.
- Trial name
- ANSTROKE (NCT01872884)
- Testing
- Sevorane Remifentanil, Remifentanil
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Sahlgrenska University Hospital
Conductive Hearing Loss, Tinnitus
Brain Mechanism and Outcome of Surgical Intervention of Conductive Hearing Loss.
This study explores the brain region activation and remodeling of poor connections of brain regions in the postoperative outcomes of conductive hearing loss patients with tinnitus by comparing pre - and post-operative…
- Conditions
- Conductive Hearing Loss, Tinnitus, Surgery
- Trial name
- NCT06535282
- Testing
- surgery
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Stroke, Shoulder Injury
STRIPS: Shoulder Taping Reduces Injury and Pain in Stroke
Background and Rationale: The most commonly seen disabilities in stroke patients are shoulder injuries such as shoulder pain, glenohumeral subluxation, spasticity of shoulder muscles, soft-tissue trauma, rotator cuff tears, and…
- Trial name
- STRIPS (NCT01062308)
- Where
- 2 sites in India
- Volunteers
- 162 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Periapical Periodontitis, Root Canal Infection
The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success
This study evaluates postoperative pain and radiographic healing of asymptomatic posterior teeth with chronic apical periodontitis following root-canal treatment performed using EndoActivator for irrigation activation.
- Trial name
- NCT06339905
- Testing
- Sonic Activation with EndoActivator, Control Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Vertigo, Functional Dizziness
Impact of Vertigoheel® on Patients Suffering From Bilateral Vestibulopathy and Functional Dizziness
In this study the researcher observe how vertigo symptoms change during two months of treatment with the natural medicinal product Vertigoheel©.
- Conditions
- Vertigo, Functional Dizziness, Bilateral Vestibulopathy
- Trial name
- HealVertigo (NCT05897853)
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Post Intensive Care Syndrome (PICS)
Post Intensive Care Accelerometery to Study and Support Recovery Outcomes
The primary purpose of this study is to find out whether a wrist-worn activity monitor can help healthcare professionals understand how people recover after they leave the intensive care unit (ICU), where they were cared for when…
- Trial name
- PICASSO (NCT07466446)
- Where
- 3 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Shoulder Pain, Stroke
Hemiplegic Shoulder Pain and Rotator Cuff Injuries
Hemiplegic shoulder pain (HSP) is one of most complications after stroke. HSP would impede rehabilitation programs and the motor recovery of affected upper extremity.
- Conditions
- Shoulder Pain, Stroke, Rotator Cuff Injuries
- Trial name
- NCT02465853
- Testing
- Hyaluronic Acid, Physiological saline solution, physical therapy and occupational therapy
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Chang Gung Memorial Hospital
Ischemic Brain Injury
Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients
The main purpose of this study is to explore whether xenon is neuroprotective in humans. In addition, the purpose is to explore the underlying mechanisms for the possible synergistic neuroprotective interaction of xenon and…
- Trial name
- Xe-hypotheca (NCT00879892)
- Testing
- xenon, Hypothermia
- Where
- 10 sites in United States, Finland
- Volunteers
- 110 people
- Sponsor
- Turku University Hospital
Infarction, Middle Cerebral Artery
Thrombectomy Under Reopro Versus Alteplase to Treat Stoke
Intravenous (IV) Alteplase (rt-PA) is the gold standard for brain infarction within 4 h 30 of symptoms onset. Efficacy of this therapy is limited in the setting of large artery occlusions.
- Trial name
- TURANDOT (NCT02016547)
- Testing
- abciximab IV and thrombectomy, alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- SOS Attaque Cérébrale
Oropharynx Cancer, Pain
Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma
To investigate the treatment related effects of transoral robotic surgery (TORS) or oncological treatment of oropharyngeal squamous cell carcinoma with a 1-year follow up.
- Conditions
- Oropharynx Cancer, Pain, Swallowing Disorder, Quality of Life
- Trial name
- NCT03418909
- Testing
- Primary Trans Oral Robotic Surgery (TORS), Radio(chemo)therapy
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Anxiety
Mobilization Protocol for Knee Arthroplasty Patients
This randomized controlled study evaluates the effect of mobilization protocol applied to knee arthroplasty patients on anxiety level, pain, mobility and functional status.
- Conditions
- Pain, Anxiety, Physical Function, Mobility
- Trial name
- KA-Mobility (NCT05679947)
- Testing
- Mobilization protocol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Gazi University
Coronary Artery Bypass Grafting
Complement Activation and Central Nervous System Injury After Coronary Artery Surgery
The impact of the postoperative inflammatory response on the central nervous system after cardiac surgery is uncertain. The goal of this study was to evaluate the role of complement activation on cellular brain injury and…
- Trial name
- NCT00188006
- Testing
- heparin-coated cardiopulmonary bypass
- Sponsor
- University Hospital, Angers
Hunter Syndrome
Hunter Outcome Survey (HOS)
The purpose of this study is to collect data that will increase understanding of Hunter syndrome. The data from HOS may provide guidance to healthcare professionals about disease treatment options.
- Trial name
- HOS (NCT03292887)
- Where
- United States
- Volunteers
- 1,443 people
- Sponsor
- Shire
Delirium, Alzheimer Disease
Improving the Recovery and Outcome Every Day After the ICU
Primary Specific Aim: Determine the effect of the combined physical exercise and cognitive training on the cognitive function of ICU survivors aged 50 and older.
- Trial name
- IMPROVE (NCT03095417)
- Testing
- Physical Exercise Intervention, Cognitive Training Intervention, Stretching Control
- Where
- 6 sites in United States
- Volunteers
- 249 people
- Sponsor
- Indiana University
Delirium, Pain
Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impact on Outcome Indicators and Economic Indicators
Retrospective cohort study to investigate the adherence to the process indicators for pain management, sedation management and management of delirium on outcome indicators and cost/revenues in individual patients and subcohorts.
- Trial name
- NCT05384613
- Where
- Germany
- Volunteers
- 20,220 people
- Sponsor
- Charite University, Berlin, Germany
Obesity, Hypercholesterolemia
The Effect of CBT- Based Weight Loss Program on Obesity
The investigators purpose is to study how CBT (cognitive behavioral therapy)-based weight loss program affects on eating behavior, weight loss and risk factors for CHD (coronary heart diseases)and type 2 diabetes.
- Conditions
- Obesity, Hypercholesterolemia, Diabetes Mellitus, Type 2, Anhedonia
- Trial name
- CognObe (NCT01606904)
- Testing
- Cognitive behavioral therapy -based weight loss program
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- University of Oulu
Seizures, Traumatic Brain Injury
Seizures and Traumatic Brain Injury Rehabilitation
post-traumatic seizures (PTS) are a common and debilitating complication of traumatic brain injury (TBI) and could have harmful impact on patient disabilty and rehabilitation outcome.
- Trial name
- NCT05823168
- Testing
- Antiepileptic Drug
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Critical Illness, Sepsis
Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation (ProCCESs AWARE)
In this multicenter project, we will introduce AWARE (electronic interface) Using a cloud-based technology . The goal of this project is to improve compliance with best practice through the use of a new acute care interface with…
- Conditions
- Critical Illness, Sepsis, Respiratory Failure, Shock
- Trial name
- AWARE (NCT02039297)
- Testing
- Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation
- Where
- 6 sites in United States
- Volunteers
- 7,813 people
- Sponsor
- Mayo Clinic
Seizure, Epileptic, Neuropsychology
Effect of the New Definition of Epilepsies of the ILAE of 2014 on the Diagnosis After the First Seizure
The present study is a prospective study on the development of seizure frequency, medication adherence, quality of life and cognitive performance after a first epileptic seizure using the new diagnostic criteria for epilepsy of…
- Conditions
- Seizure, Epileptic, Neuropsychology, Outcome
- Trial name
- EFS-ILAE2014 (NCT06836687)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University Hospital Marburg