Clinical trials: Neurological Outcome
Muscle Soreness
Does Placebo Information Affect the Trial Outcomes and Participant Blinding?
This is a randomised sham-controlled trial involving healthy volunteers to determine the effect of information on placebo, i.e., sham acupuncture, given in the informed consent, on the trial outcomes and blinding status of…
- Trial name
- NCT04182295
- Testing
- acupuncture
- Where
- South Korea
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Kyunghee University
Pain
Acupuncture for Pain Relief During Induced Labour in Nulliparae
The study was primarily designed to assess the role of acupuncture in reducing the need for epidural analgesia for pain relief during induced labour. The other outcomes of labour were to be observed in addition.
- Trial name
- NCT01165099
- Testing
- acupuncture
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- University of Oxford
Brain Injuries, Traumatic
Impact of Early Optimization of Brain Oxygenation on Neurological Outcome After Severe Traumatic Brain Injury
Post-traumatic brain hypoxia/ischemia develops hours after traumatic brain injury (TBI), and its intensity is directly related to the neurological outcome.
- Trial name
- OXY-TC (NCT02754063)
- Testing
- PbtO2 probes, No PbtO2 probes
- Where
- 26 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Grenoble
Intellectual Disability, Perceptual Disorders
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
The purpose of this study is to determine the relationships between sedative exposure during pediatric critical illness and long-term neurocognitive outcomes.
- Conditions
- Intellectual Disability, Perceptual Disorders, Memory Disorders
- Trial name
- RESTORE-cog (NCT02225041)
- Where
- 31 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Degenerative Lumbar Spinal Stenosis, Neurologic Intermittent Claudication
Clinical and Radiological Outcomes Following Insertion of a Novel Removable Percutaneous Interspinous Process Spacer: an Initial Experience.
Purpose To evaluate clinical and radiologic outcome of a series of patients treated with a removable percutaneous interspinous process spacer (IPS) (LobsterProject® Techlamed®) for symptomatic degenerative lumbar spinal stenosis…
- Trial name
- LOBSTER (NCT05203666)
- Testing
- percutaneous removable interspinous process
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spinocerebellar Ataxia Type 27B
Spinocerebellar Ataxia Type 27B Natural History Study (SCA27B-NHS)
This international, multi-center, multi-modal, and prospective observational cohort study aims to validate trial outcomes for capturing disease progression in Spinocerebellar Ataxia Type 27B (SCA27B), with combined multi-modal…
- Trial name
- NCT06472557
- Where
- 5 sites in Czechia, Germany and 2 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Stroke
Nutritional Status in Subacute Stroke Patients Under Rehabilitation
Recently, is becoming more evident a relationship between malnutrition, stroke-related sarcopenia and/or altered systemic oxidative status in patients with subacute stroke .
- Trial name
- Nutristroke (NCT04923165)
- Testing
- robotic assisted intervention, biochemical analyses, BIA, hand grip
- Where
- Italy
- Volunteers
- 119 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Spasticity
Study Assessing Adult Subjects Affected With Upper and/or Lower Limb Spasticity Treated With Botulinum Neurotoxin Type A
The aim of the study is to describe the long term use of Botulinum Neurotoxin Type A (BoNT-A) in adult subjects affected with upper and/or lower limb spasticity who received treatment with BoNT-A for a minimum of three injections…
- Trial name
- RESULT (NCT04340336)
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Ipsen
Procedural Sedation, Gastrointestinal Endoscopy
Therapeutic Effects of Music on Procedural Outcomes
This study will evaluate whether listening to low-tempo instrumental music during gastroscopy and/or colonoscopy can reduce the amount of sedative medication needed during the procedure.
- Conditions
- Procedural Sedation, Gastrointestinal Endoscopy, Music Intervention
- Trial name
- TEMPO (NCT07763860)
- Testing
- Low-Tempo Instrumental Music, Silent Audio Control
- Where
- Lebanon
- Volunteers
- 180 people
- Sponsor
- Bahaa Bou Dargham
Diplegia, Spastic
Eye-Hand Coordination in Children With Spastic Diplegia
This study will examine how the brain controls eye-hand coordination (visuomotor skills) in children with spastic diplegia and will determine whether impairment of this skill is related to the learning difficulties in school that…
- Trial name
- NCT00024791
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Status Epilepticus, Convulsive Status Epilepticus
Predictors of Outcomes of Convulsive Status Epilepticus
Status epilepticus is a life-threatening neurological emergency characterized by prolonged seizures or multiple seizures occurring without the patient regaining consciousness between episodes.
- Trial name
- NCT07853391
- Volunteers
- 100 people
- Sponsor
- Assiut University
Uterine Myoma, Uterine Adenomyosis
Single Incision Laparoscopic Surgery (SILS) Versus Conventional Laparoscopic Hysterectomy
Multi-center prospective randomized trial of single port laparoscopic surgery (SILS) versus conventional 3-4 ports laparoscopic hysterectomy.
- Trial name
- NCT01483417
- Testing
- Single incision Laparoscopic hysterectomy, Conventional laparoscopic hysterectomy
- Where
- 8 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Cardiac Arrest
Circulating Biomarkers Predict Neurological Outcome After Cardiac Arrest
Prediction of clinical outcome after cardiac arrest is clinically important.Early prognostication after successful cardiopulmonary resuscitation is difficult, and there is a need for novel methods to estimate the extent of brain…
- Trial name
- CABNO (NCT02297776)
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai 10th People's Hospital
Shoulder Pain, Rotator Cuff Injury
Does The Type of Exercise Influence Outcome in Rotator Cuff Related Shoulder Pain
Rotator cuff related shoulder pain (RCRSP) is the most common shoulder disorder and its chronicization leads to multiple consequences such as early retirement, absenteeism from work, decreased participation and quality of life…
- Conditions
- Shoulder Pain, Rotator Cuff Injury, Rotator Cuff Tendinitis, Rotator Cuff Impingement Syndrome
- Trial name
- RCT-RCRSP (NCT03892603)
- Testing
- Strengthening exercises program, Motor control exercises program, Education and advice
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Laval University
Encephalitis
Epidemiology and Prognosis of Encephalitis in Intensive Care
Introduction: Acute encephalitis (AE) is a severe neurological disorder associated with significant morbidity and mortality. Approximately 50% of patients with AE require ICU admission because of coma, seizures or acute…
- Trial name
- ENCEPHALITICA (NCT02906631)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ptosis, Eyelid
Efficacy of Aurosling in Frontalis Sling Suspension Surgery
To Study the Efficacy of Aurosling as a suspension material in Frontalis suspension surgery in ptosis
- Trial name
- NCT00753831
- Testing
- Aurosling
- Where
- India
- Volunteers
- 16 people
- Sponsor
- Aurolab
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Brain Injury, Coma
Brain Death and Organ Donation in Tunisian Intensive Care Units
The goal of this observational study was to identify factors associated with the progression to brain death in critically ill patients with severe brain injuries in Tunisian intensive care units (ICUs).
- Conditions
- Brain Injury, Coma, Organ Transplants
- Trial name
- BDOD-TN (NCT06948669)
- Where
- Tunisia
- Volunteers
- 104 people
- Sponsor
- Faculty of Medicine, Sousse
Extra Corporeal Membrane Oxygenation
Acute Neurological Complications and Neurodevelopmental Outcome in Children Undergoing Extracorporeal Membrane Oxygenation.
The purpose of this retrospective study is to describe the different types of acute neurologic complications in children who underwent extracorporeal membrane oxygenation (ECMO), and their risk factors.
- Trial name
- NeurECMO (NCT04519528)
- Testing
- DENVER scale (under 2 years old) or Pediatric Cerebral Performance Category (PCPC) score (over 2 years old), Pediatric Quality of Life Inventory™ (PedsQL)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Cardiac Arrest Patient Who Was Treated by Hypothermia Protocol
Plasma Neutrophil Gelatinase-associated Lipocalin (NGAL) as Early Biomarker for Renal Dysfunction and Good Neurologic Outcome in Out of Hospital Cardiac Arrest Patients
Postresuscitation disease is a constellation of disorders related to whole-body ischemia and reperfusion syndrome. It includes hypoxic damage in brain, liver, kidney, heart and other organ.
- Trial name
- NCT01987466
- Testing
- Serum NGAL level
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Yonsei University